phrog_4617 is made of 29 protein sequences and is annotated as "replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
98.21 236 100


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p63630 no NCBI prot ID no annotation VI_05511 Betaproteobacteria_gi_149146613_0_50926 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_005284_p70 NP_945100.1 gp69 NC_005284 Burkholderia virus phi1026b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
p83725 no NCBI prot ID no annotation VI_05550 Betaproteobacteria_gi_485035271_0_47405 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p191109 no NCBI prot ID no annotation VI_05506 Betaproteobacteria_gi_149127571_0_37136 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_009235_p58 YP_001111137.1 gp58 NC_009235 Burkholderia virus phi6442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
NC_003309_p60 NP_536416.1 hypothetical protein NC_003309 Burkholderia virus phiE125 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
p329417 no NCBI prot ID no annotation VI_11465 Gammaproteobacteria_gi_544943743 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p325690 no NCBI prot ID no annotation VI_08051 Gammaproteobacteria_gi_419260294 Viruses.
p299991 no NCBI prot ID no annotation VI_08034 Gammaproteobacteria_gi_419248270 Viruses.
p122288 no NCBI prot ID no annotation VI_07163 Gammaproteobacteria_gi_417230772_0_43149 Viruses.
p63761 no NCBI prot ID no annotation VI_01645 Gammaproteobacteria_gi_545250371_3663255_3714136 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p86529 no NCBI prot ID no annotation VI_07781 Gammaproteobacteria_gi_419034851_54108_101048 Viruses.
p340618 no NCBI prot ID no annotation VI_07182 Gammaproteobacteria_gi_417263098_0_21114 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Enterobacteria phage phiP27.
p20859 no NCBI prot ID no annotation VI_02754 Gammaproteobacteria_gi_476380707_486558_562638 Viruses.
p287851 no NCBI prot ID no annotation VI_02326 Gammaproteobacteria_gi_476380890_0_27500 Viruses.
p113638 no NCBI prot ID no annotation VI_01390 Gammaproteobacteria_gi_545162641_54_44250 Viruses.
p151172 no NCBI prot ID no annotation VI_09162 Gammaproteobacteria_gi_483306993_249971_290685 Viruses.
p138445 no NCBI prot ID no annotation VI_07477 Gammaproteobacteria_gi_418300889_2236016_2277962 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p187460 no NCBI prot ID no annotation VI_01388 Gammaproteobacteria_gi_545162157_105261_142734 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p52657 no NCBI prot ID no annotation VI_02547 Gammaproteobacteria_gi_262045650 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p225169 no NCBI prot ID no annotation VI_07172 Gammaproteobacteria_gi_417244487_277124_311426 Viruses.
p339428 no NCBI prot ID no annotation VI_08169 Gammaproteobacteria_gi_419338217 Viruses.
p138952 no NCBI prot ID no annotation VI_01504 Gammaproteobacteria_gi_545232615_3175131_3217045 Viruses.
p185275 no NCBI prot ID no annotation VI_07269 Gammaproteobacteria_gi_417615901_254373_292104 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p89250 no NCBI prot ID no annotation VI_07344 Gammaproteobacteria_gi_417830908_67840_114343 Viruses.
p289660 no NCBI prot ID no annotation VI_07759 Gammaproteobacteria_gi_419016229_53909_81111 Viruses.
p173045 no NCBI prot ID no annotation VI_09626 Gammaproteobacteria_gi_433178711 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p53897 no NCBI prot ID no annotation VI_01386 Gammaproteobacteria_gi_545162041 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_010237_p29 YP_001648920.1 putative replication protein O NC_010237 Escherichia phage Min27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Sepvirinae; Traversvirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_270 446 replication initiation protein DNA, RNA and nucleotide metabolism 16 3.23E-43 33.61
phrog_1153 130 no annotation unknown function 10 4.40E-32 22.48
phrog_1033 143 ParB-like partition protein DNA, RNA and nucleotide metabolism 6 4.44E-19 9.47
phrog_821 175 transcriptional regulator transcription regulation 5 1.43E-15 5.97
phrog_678 208 replication initiation O-like DNA, RNA and nucleotide metabolism 4 2.16E-12 2.79
phrog_34472 2 no annotation unknown function 2 0 1000
phrog_26426 3 replication protein DNA, RNA and nucleotide metabolism 2 2.16E-13 3.79
phrog_20981 4 no annotation unknown function 2 8.64E-13 3.19

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1032 replication initiation protein DNA, RNA and nucleotide metabolism 99.4 9.9E-17 3-76 / 4-75
phrog_10724 no annotation unknown function 93.8 0.0069 33-72 / 28-65
phrog_1098 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.5 0.034 21-74 / 21-75
phrog_11896 primosomal protein DNA, RNA and nucleotide metabolism 98.4 1.7E-10 17-99 / 21-95
phrog_12720 DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.005 22-65 / 35-76
phrog_13105 no annotation unknown function 90.0 0.063 40-74 / 21-55
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 96.5 2.7E-05 34-73 / 9-47
phrog_15053 no annotation unknown function 92.5 0.019 25-95 / 43-106
phrog_1835 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.0 0.0014 17-95 / 50-123
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 96.6 2.3E-05 14-76 / 24-88
phrog_19658 replication initiation protein DNA, RNA and nucleotide metabolism 93.7 0.0071 15-74 / 18-74
phrog_2030 transcriptional regulator transcription regulation 90.7 0.048 38-73 / 114-154
phrog_21868 no annotation unknown function 93.9 0.0061 39-92 / 61-110
phrog_24920 no annotation unknown function 94.6 0.0028 40-94 / 27-70
phrog_26369 replication initiation protein DNA, RNA and nucleotide metabolism 93.3 0.01 30-69 / 74-111
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 98.9 1.3E-12 12-96 / 15-90
phrog_345 replication initiation O-like DNA, RNA and nucleotide metabolism 96.5 3.8E-05 9-73 / 41-108
phrog_3502 no annotation unknown function 94.8 0.0021 15-74 / 5-62
phrog_362 transcriptional repressor transcription regulation 94.6 0.0028 40-73 / 27-61
phrog_391 replication initiation O-like DNA, RNA and nucleotide metabolism 99.6 5.3E-19 5-98 / 10-94
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 97.3 7.7E-07 18-75 / 30-85
phrog_5978 no annotation unknown function 92.1 0.024 37-74 / 319-356
phrog_6643 replication initiation protein DNA, RNA and nucleotide metabolism 97.3 1.1E-06 4-72 / 5-71
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 97.1 2E-06 34-98 / 45-102
phrog_7498 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 95.2 0.001 20-74 / 29-92
phrog_7882 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 90.2 0.06 18-79 / 39-98
phrog_8102 replication initiation protein DNA, RNA and nucleotide metabolism 97.1 2.1E-06 15-75 / 22-84
phrog_8540 replication initiation O-like DNA, RNA and nucleotide metabolism 99.8 9.7E-23 2-97 / 3-94
phrog_9088 no annotation unknown function 95.1 0.0012 21-79 / 47-103
phrog_9285 no annotation unknown function 95.4 0.00068 18-72 / 16-68

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 1.1E-05 11-71 / 22-83
PF05584.10 Sulfolobus plasmid regulatory protein 5.6E-05 16-71 / 5-52
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 6.3E-05 16-71 / 7-56
PF03965.15 Penicillinase repressor 6.6E-05 17-91 / 3-71
PF01978.18 Sugar-specific transcriptional regulator TrmB 7.4E-05 16-71 / 7-56
PF07381.10 Winged helix DNA-binding domain (DUF1495) 8.7E-05 16-71 / 8-68
PF16221.4 winged helix-turn-helix 0.00011 18-69 / 32-78
PF03551.13 Transcriptional regulator PadR-like family 0.00011 36-91 / 13-69
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.00013 19-70 / 9-56
PF04079.15 Segregation and condensation complex subunit ScpB 0.00015 11-95 / 78-150
PF02295.16 Adenosine deaminase z-alpha domain 0.00014 18-70 / 5-52
PF13463.5 Winged helix DNA-binding domain 0.00015 18-70 / 4-50
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00016 16-70 / 12-60
PF13601.5 Winged helix DNA-binding domain 0.00016 21-71 / 4-48
PF11313.7 Protein of unknown function (DUF3116) 0.00018 37-94 / 20-79
PF14277.5 Domain of unknown function (DUF4364) 0.00017 21-94 / 4-70
PF14557.5 Putative AphA-like transcriptional regulator 0.00026 12-97 / 4-90
PF04358.12 DsrC like protein 0.00029 11-70 / 34-94
PF14947.5 Winged helix-turn-helix 0.00027 20-92 / 5-66
PF09114.9 Transcription factor MotA, activation domain 0.00029 11-69 / 11-63
PF09202.10 Rio2, N-terminal 0.0003 16-92 / 5-72
PF08222.10 CodY helix-turn-helix domain 0.00035 36-71 / 3-38
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00038 36-71 / 23-58
PF01475.18 Ferric uptake regulator family 0.00044 16-88 / 6-73
PF05732.10 Firmicute plasmid replication protein (RepL) 0.00045 12-70 / 50-108
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00047 16-71 / 11-60
PF03428.12 Replication protein C N-terminal domain 0.00054 8-71 / 35-105
PF09012.9 FeoC like transcriptional regulator 0.00053 36-71 / 13-48
PF02002.16 TFIIE alpha subunit 0.00057 18-71 / 13-60
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00061 19-71 / 3-52
PF02082.19 Transcriptional regulator 0.00063 38-70 / 25-57
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00068 36-71 / 17-52
PF12802.6 MarR family 0.00066 38-71 / 22-55
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.0007 16-70 / 7-59
PF14394.5 Domain of unknown function (DUF4423) 0.00076 17-71 / 21-72
PF08461.9 Ribonuclease R winged-helix domain 0.00078 36-70 / 11-50
PF07848.11 PaaX-like protein 0.00082 36-71 / 19-57
PF01638.16 HxlR-like helix-turn-helix 0.00089 19-71 / 7-54
PF09182.9 Bacterial purine repressor, N-terminal 0.00091 19-69 / 6-57
PF01022.19 Bacterial regulatory protein, arsR family 0.00093 36-67 / 15-46
PF08784.10 Replication protein A C terminal 0.0011 16-71 / 39-95
PF01090.18 Ribosomal protein S19e 0.0012 20-71 / 54-114
PF13412.5 Winged helix-turn-helix DNA-binding 0.0011 36-67 / 16-47
PF01047.21 MarR family 0.0012 19-71 / 5-51
PF01726.15 LexA DNA binding domain 0.0013 36-71 / 24-60
PF04703.11 FaeA-like protein 0.0012 36-71 / 13-48
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.0016 16-94 / 4-77
PF01316.20 Arginine repressor, DNA binding domain 0.0015 18-71 / 6-55
PF08220.11 DeoR-like helix-turn-helix domain 0.0015 36-69 / 13-46
PF09339.9 IclR helix-turn-helix domain 0.0017 37-69 / 18-50
PF02334.15 Replication terminator protein 0.002 36-94 / 30-100
PF05158.11 RNA polymerase Rpc34 subunit 0.0021 13-71 / 89-142
PF16864.4 Dimerisation domain 0.0021 19-69 / 20-64
PF10711.8 Hypothetical protein (DUF2513) 0.0023 19-71 / 7-56
PF09904.8 Winged helix-turn helix 0.0024 36-69 / 20-53
PF09639.9 YjcQ protein 0.0025 36-95 / 15-81
PF04182.11 B-block binding subunit of TFIIIC 0.0028 36-71 / 17-52
PF12840.6 Helix-turn-helix domain 0.0031 16-70 / 7-53
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0031 36-69 / 16-49
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0037 16-71 / 7-56
PF09824.8 ArsR transcriptional regulator 0.0041 16-70 / 16-61
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0037 36-70 / 20-54
PF15977.4 Winged helix-turn-helix DNA binding 0.0041 36-70 / 22-56
PF06969.15 HemN C-terminal domain 0.0047 36-69 / 19-53
PF14502.5 Helix-turn-helix domain 0.0052 36-70 / 5-39

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:DNA replication protein 1:replication protein O

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0003700 DNA binding transcription factor activity
GO:0006468 protein phosphorylation
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0007131 reciprocal meiotic recombination
GO:0009378 four-way junction helicase activity
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0006260 DNA replication
GO:0009289 pilus
GO:0004674 protein serine/threonine kinase activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0004252 serine-type endopeptidase activity
GO:0006281 DNA repair

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