phrog_4646 is made of 29 protein sequences and is annotated as "transposase"
Functional category: integration and excision


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
345.03 546 346


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p296638 no NCBI prot ID no annotation VI_05559 Betaproteobacteria_gi_416182996_9218_35501 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p338789 no NCBI prot ID no annotation VI_01139 Clostridia_gi_545644394 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p40436 no NCBI prot ID no annotation VI_04047 unknown_gi_547191751 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Vibrio phage X29.
MG711461_p37 AUV56389.1 integrase MG711461 Faecalibacterium phage FP_Lagaffe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Lagaffevirus; Faecalibacterium virus Lagaffe.
p59315 no NCBI prot ID no annotation VI_01197 Clostridia_gi_355635008_30994_83331 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p176442 no NCBI prot ID no annotation VI_05560 Betaproteobacteria_gi_416196569 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_023499_p30 YP_009002786.1 putative transposase NC_023499 Staphylococcus phage StauST398-4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Biseptimavirus; unclassified Biseptimavirus.
p373413 no NCBI prot ID no annotation VI_04603 Bacilli_gi_418004195 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p71193 no NCBI prot ID no annotation VI_01189 Clostridia_gi_283767241_16075_65536 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p127214 no NCBI prot ID no annotation VI_01263 Clostridia_gi_547888572_0_42670 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p87531 no NCBI prot ID no annotation VI_01285 Clostridia_gi_551720650_456133_502893 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p428190 no NCBI prot ID no annotation VI_05173 Bacilli_gi_511739624 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p24144 no NCBI prot ID no annotation VI_01162 Clostridia_gi_211596814 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p15343 no NCBI prot ID no annotation VI_01194 Clostridia_gi_373121103_353147_435681 Viruses.
p255830 no NCBI prot ID no annotation VI_01237 Clostridia_gi_547766152_28262_59617 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_002486_p65 NP_061653.1 transposase NC_002486 Staphylococcus prophage phiPV83 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Biseptimavirus; unclassified Biseptimavirus.
p17180 no NCBI prot ID no annotation VI_09489 Gammaproteobacteria_gi_484030090 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p417702 no NCBI prot ID no annotation VI_01220 Clostridia_gi_546939731_162301_174407 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p78302 no NCBI prot ID no annotation VI_01154 Clostridia_gi_256402711_179985_228048 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p413182 no NCBI prot ID no annotation VI_12305 Negativicutes_gi_401563568 Viruses.
p442290 no NCBI prot ID no annotation VI_00962 Bacilli_gi_289166909_738608_743776 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Plectroviridae; Vespertiliovirus; Spiroplasma virus R8A2B; Spiroplasma phage R8A2B.
p442289 no NCBI prot ID no annotation VI_00962 Bacilli_gi_289166909_738608_743776 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Plectroviridae; Vespertiliovirus; Spiroplasma virus R8A2B; Spiroplasma phage R8A2B.
p442291 no NCBI prot ID no annotation VI_00962 Bacilli_gi_289166909_738608_743776 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Plectroviridae; Vespertiliovirus; Spiroplasma virus R8A2B; Spiroplasma phage R8A2B.
X51344_p5 CAA35729.1 no annotation X51344 Spiroplasma phage 1-R8A2B Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Plectroviridae; Vespertiliovirus; Spiroplasma virus R8A2B.
NC_001365_p5 NP_040341.1 putative transposase NC_001365 Spiroplasma phage 1-R8A2B Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Plectroviridae; Vespertiliovirus; Spiroplasma virus R8A2B.
p391711 no NCBI prot ID no annotation VI_04159 Actinobacteria_gi_544933272 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p391002 no NCBI prot ID no annotation VI_04078 Actinobacteria_gi_257461662 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p331334 no NCBI prot ID no annotation VI_04001 Negativicutes_gi_545446850 Viruses.
p443090 no NCBI prot ID no annotation VI_11990 Gammaproteobacteria_gi_566137214_0_4070 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3 3832 transcriptional repressor transcription regulation 8 1.17E-14 5.05
phrog_4646 29 transposase integration and excision 4 4.86E-18 8.44
phrog_29948 2 no annotation unknown function 2 0 1000
phrog_16020 6 no annotation unknown function 2 8.16E-13 3.21
phrog_31723 2 no annotation unknown function 2 0 1000
phrog_14869 6 no annotation unknown function 2 8.16E-13 3.21

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11302 no annotation unknown function 99.6 2.4E-20 3-109 / 2-94
phrog_11376 no annotation unknown function 92.2 0.023 6-49 / 42-85
phrog_11420 DNA binding protein DNA, RNA and nucleotide metabolism 99.4 2.1E-17 2-80 / 5-81
phrog_1157 transposase integration and excision 97.9 1.7E-08 7-345 / 2-300
phrog_12823 no annotation unknown function 91.1 0.041 2-51 / 8-57
phrog_13695 no annotation unknown function 99.6 2E-19 163-231 / 2-69
phrog_151 transposase integration and excision 91.4 0.036 3-49 / 3-50
phrog_157 transposase integration and excision 97.1 2.3E-06 188-342 / 112-267
phrog_16079 no annotation unknown function 99.3 1.2E-15 190-259 / 1-66
phrog_1740 RNA polymerase sigma factor transcription regulation 92.5 0.019 4-49 / 124-169
phrog_20133 no annotation unknown function 98.8 2E-12 3-87 / 2-85
phrog_20487 no annotation unknown function 100.0 5.6E-38 3-199 / 2-182
phrog_2538 terminase small subunit head and packaging 93.7 0.0076 7-46 / 4-43
phrog_25415 no annotation unknown function 90.1 0.061 124-174 / 1-49
phrog_27475 no annotation unknown function 96.6 2.6E-05 7-344 / 2-299
phrog_310 transposase integration and excision 97.1 2.6E-06 95-342 / 192-459
phrog_3218 terminase small subunit head and packaging 91.1 0.041 2-43 / 14-54
phrog_3512 sigma factor transcription regulation 92.9 0.014 6-48 / 66-108
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.8 0.047 12-47 / 69-104
phrog_3910 transcriptional regulator transcription regulation 92.3 0.022 3-44 / 59-101
phrog_3 transcriptional repressor transcription regulation 90.1 0.062 19-47 / 13-40
phrog_4410 no annotation unknown function 100.0 1.1E-66 171-344 / 1-166
phrog_4494 no annotation unknown function 93.9 0.006 12-49 / 7-44
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0038 5-43 / 62-100
phrog_5536 no annotation unknown function 94.6 0.0027 6-48 / 5-47
phrog_5904 no annotation unknown function 99.9 4.3E-27 257-341 / 2-84
phrog_6223 transcriptional repressor transcription regulation 94.2 0.0042 19-83 / 14-69
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 95.9 0.00021 7-139 / 4-95
phrog_66 excisionase and transcriptional regulator integration and excision 92.5 0.018 21-47 / 8-34
phrog_6831 transcriptional regulator transcription regulation 92.9 0.015 12-42 / 5-35
phrog_7676 no annotation unknown function 91.6 0.032 19-54 / 13-48
phrog_7847 no annotation unknown function 95.6 0.00046 7-231 / 2-168
phrog_8463 transposase integration and excision 98.0 7.1E-09 15-338 / 18-309
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0027 23-52 / 19-48

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04936.11 Protein of unknown function (DUF658) 4.1E-08 43-125 / 14-115
PF02914.14 Bacteriophage Mu transposase 1.7E-07 276-407 / 31-214
PF08822.10 Protein of unknown function (DUF1804) 0.005 85-126 / 5-47
PF00292.17 'Paired box' domain 0.0011 82-126 / 17-61
PF01710.15 Transposase 8.2E-07 27-124 / 3-96
PF00665.25 Integrase core domain 7.7E-06 275-367 / 26-134
PF13610.5 DDE domain 1.6E-05 276-392 / 18-135
PF04552.12 Sigma-54, DNA binding domain 0.00012 40-125 / 45-152
PF07750.10 GcrA cell cycle regulator 0.0057 83-125 / 3-46
PF15978.4 Tn7-like transposition protein D 0.00034 31-122 / 191-295
PF13411.5 MerR HTH family regulatory protein 0.00038 45-70 / 2-27
PF13011.5 leucine-zipper of insertion element IS481 0.0004 27-69 / 8-50
PF09607.9 Brinker DNA-binding domain 0.00044 26-68 / 5-50
PF14493.5 Helix-turn-helix domain 0.00046 39-69 / 8-38
PF05344.10 Domain of Unknown Function (DUF746) 0.00048 34-69 / 3-38
PF12759.6 InsA C-terminal domain 0.0096 87-122 / 10-45
PF07141.10 Putative bacteriophage terminase small subunit 0.0074 88-124 / 21-57
PF16087.4 Domain of unknown function (DUF4817) 0.00072 29-69 / 2-50
PF13309.5 HTH domain 0.0013 30-65 / 23-63
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0014 38-68 / 8-38
PF10654.8 Protein of unknown function (DUF2481) 0.0015 34-66 / 71-103
PF06322.10 Phage NinH protein 0.0016 34-68 / 7-41
PF13358.5 DDE superfamily endonuclease 0.0018 319-371 / 80-133
PF07592.10 Rhodopirellula transposase DDE domain 0.0024 317-371 / 180-244
PF06627.10 Protein of unknown function (DUF1153) 0.0026 24-69 / 27-72
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.0028 30-67 / 6-43
PF05225.15 helix-turn-helix, Psq domain 0.003 32-66 / 5-40
PF10668.8 Phage terminase small subunit 0.0032 31-69 / 8-48
PF08765.10 Mor transcription activator family 0.0035 36-68 / 66-97
PF02796.14 Helix-turn-helix domain of resolvase 0.0043 39-66 / 17-44
PF07900.10 Protein of unknown function (DUF1670) 0.0046 41-123 / 93-177
PF12116.7 Stage III sporulation protein D 0.005 39-66 / 15-42
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.0051 33-67 / 45-79
PF04218.12 CENP-B N-terminal DNA-binding domain 0.0056 41-67 / 21-47
PF10975.7 Protein of unknown function (DUF2802) 0.0054 29-65 / 29-65
PF02954.18 Bacterial regulatory protein, Fis family 0.0064 41-66 / 14-39
PF01527.19 Transposase 0.0065 28-68 / 6-46
PF05331.10 Protein of unknown function (DUF742) 0.0066 32-67 / 43-77
PF07453.12 NUMOD1 domain 0.0088 43-64 / 19-40
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0097 29-66 / 14-49

Annotations of the NCBI proteins of this PHROG


3:transposase 1:integrase 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07482 K07482 : transposase, IS30 family no pathways 652 2

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0005524 ATP binding
GO:0015074 DNA integration
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly

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