phrog_4681 is made of 29 protein sequences and is annotated as "antitoxin from a toxin-antitoxin system"
Functional category: moron, auxiliary metabolic gene and host takeover


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
94.41 162 87


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p53929 no NCBI prot ID no annotation VI_05779 Clostridia_gi_416372985 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p59106 no NCBI prot ID no annotation VI_05775 Clostridia_gi_416348160_2570_54993 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p235311 no NCBI prot ID no annotation VI_01196 Clostridia_gi_355632064_60118_93388 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p38134 no NCBI prot ID no annotation VI_05808 Clostridia_gi_484142200 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p191204 no NCBI prot ID no annotation VI_04070 unknown_gi_557506924_0_37126 Viruses.
p267820 no NCBI prot ID no annotation VI_06203 Clostridia_gi_564826236 Viruses.
p110559 no NCBI prot ID no annotation VI_01281 Clostridia_gi_160878162_3615270_3659755 Viruses.
MG727697_p48 AUS03448.1 transcriptional regulator MG727697 Paenibacillus phage Dragolir Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vegasvirus; unclassified Vegasvirus.
KC595516_p72 AGR47438.2 AbrB family transcriptional regulator KC595516 Brevibacillus phage Emery Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p172454 no NCBI prot ID no annotation VI_05814 Clostridia_gi_544703850 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_019515_p49 YP_007005900.1 transcriptional regulator AbrB family NC_019515 Bacillus phage BCD7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_028767_p64 YP_009196163.1 AbrB family transcriptional regulator NC_028767 Paenibacillus phage Vegas Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vegasvirus.
p122807 no NCBI prot ID no annotation VI_05802 Clostridia_gi_483046904_0_43059 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p213691 no NCBI prot ID no annotation VI_00911 Bacilli_gi_484080341 Viruses.
p98500 no NCBI prot ID no annotation VI_01213 Clostridia_gi_546162569_1631445_1676706 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p151915 no NCBI prot ID no annotation VI_00910 Bacilli_gi_484080317 Viruses.
p40728 no NCBI prot ID no annotation VI_00882 Bacilli_gi_484028336 Viruses.
p148272 no NCBI prot ID no annotation VI_00827 Bacilli_gi_296500838_2496144_2537191 Viruses.
p133571 no NCBI prot ID no annotation VI_00979 Bacilli_gi_402558824_1373424_1415725 Viruses.
p193389 no NCBI prot ID no annotation VI_00879 Bacilli_gi_507027716 Viruses.
p153164 no NCBI prot ID no annotation VI_00794 Bacilli_gi_218230750_2507426_2547955 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p74568 no NCBI prot ID no annotation VI_00703 Bacilli_gi_507048098 Viruses.
p48626 no NCBI prot ID no annotation VI_05296 Bacilli_gi_544020570 Viruses; unclassified bacterial viruses.
NC_004820_p38 NP_852518.1 Transcription state regulatory protein abrB NC_004820 Bacillus phage phBC6A51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p124768 no NCBI prot ID no annotation VI_00795 Bacilli_gi_218895141_2470312_2513147 Viruses.
p63329 no NCBI prot ID no annotation VI_00406 Bacilli_gi_423364498 Viruses.
p59424 no NCBI prot ID no annotation VI_00699 Bacilli_gi_507029665 Viruses.
KX190833_p24 ANT39984.1 antitoxin protein KX190833 Bacillus phage vB_BtS_BMBtp14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p336364 no NCBI prot ID no annotation VI_04037 Thermococci_gi_295698815 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_5641 23 no annotation unknown function 8 4.07E-33 23.51
phrog_21302 4 no annotation unknown function 3 1.16E-17 8.06
phrog_16451 6 no annotation unknown function 2 4.08E-12 2.51
phrog_28950 2 no annotation unknown function 2 0 1000
phrog_18759 4 no annotation unknown function 2 8.17E-13 3.21
phrog_26408 3 no annotation unknown function 2 2.04E-13 3.81

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10557 no annotation unknown function 92.1 0.024 15-49 / 11-45
phrog_13486 no annotation unknown function 90.2 0.059 15-49 / 15-51
phrog_36746 antitoxin from a toxin-antitoxin system moron, auxiliary metabolic gene and host takeover 99.4 2.3E-17 1-51 / 1-51
phrog_4324 no annotation unknown function 91.2 0.039 7-50 / 6-49
phrog_4921 no annotation unknown function 96.1 0.00012 5-80 / 13-86
phrog_661 no annotation unknown function 96.2 0.00011 11-49 / 12-52

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF15937.4 prlF antitoxin for toxin YhaV_toxin 1.5E-06 20-60 / 2-43
PF02381.17 MraZ protein, putative antitoxin-like 1.1E-05 65-108 / 6-47
PF14250.5 AbrB-like transcriptional regulator 4.9E-07 64-104 / 30-70
PF04014.17 Antidote-toxin recognition MazE, bacterial antitoxin 9E-07 21-59 / 2-40
PF08845.9 Toxin SymE, type I toxin-antitoxin system 1E-05 23-57 / 15-49
PF03152.13 Ubiquitin fusion degradation protein UFD1 0.00078 20-97 / 19-95

Annotations of the NCBI proteins of this PHROG


2:AbrB family transcriptional regulator 1:Transcription state regulatory protein abrB 1:antitoxin protein 1:transcriptional regulator AbrB family 1:transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K06284 abrB : transcriptional pleiotropic regulator of transition state genes no pathways 184 24

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003700 DNA binding transcription factor activity
GO:0097351 toxin-antitoxin pair type II binding
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005737 cytoplasm
GO:0016070 RNA metabolic process
GO:0016788 hydrolase activity, acting on ester bonds
GO:0001558 regulation of cell growth

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