phrog_4691 is made of 29 protein sequences and is annotated as "excisionase"
Functional category: integration and excision


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
75.14 92 78


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p211020 no NCBI prot ID no annotation VI_00698 Bacilli_gi_507028670 Viruses.
p36954 no NCBI prot ID no annotation VI_00613 Bacilli_gi_505484080 Viruses.
p12643 no NCBI prot ID no annotation VI_00424 Bacilli_gi_423496617 Viruses.
p162437 no NCBI prot ID no annotation VI_00743 Bacilli_gi_452202137 Viruses.
p12744 no NCBI prot ID no annotation VI_00425 Bacilli_gi_423502290 Viruses.
p53672 no NCBI prot ID no annotation VI_00422 Bacilli_gi_423490892 Viruses.
p38579 no NCBI prot ID no annotation VI_00405 Bacilli_gi_423364338 Viruses.
p95617 no NCBI prot ID no annotation VI_04403 Bacilli_gi_196037087_0_45570 Viruses.
p61677 no NCBI prot ID no annotation VI_00738 Bacilli_gi_384183548 Viruses.
p54892 no NCBI prot ID no annotation VI_00741 Bacilli_gi_407708681 Viruses.
MF176161_p17 ARW58267.1 transcriptional regulator MF176161 Bacillus phage Deep-Purple Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p59444 no NCBI prot ID no annotation VI_00699 Bacilli_gi_507029665 Viruses.
p35160 no NCBI prot ID no annotation VI_00711 Bacilli_gi_507055493_2793767_2856861 Viruses.
p347318 no NCBI prot ID no annotation VI_05372 Bacilli_gi_545133188 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p301141 no NCBI prot ID no annotation VI_04422 Bacilli_gi_167641861 Viruses.
p316994 no NCBI prot ID no annotation VI_04424 Bacilli_gi_170709180 Viruses.
p309809 no NCBI prot ID no annotation VI_04425 Bacilli_gi_170689508 Viruses.
MF595878_p1 ATB52688.1 helix turn helix domain protein MF595878 Caldibacillus phage CBP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p323196 no NCBI prot ID no annotation VI_04407 Bacilli_gi_190569304 Viruses.
p311060 no NCBI prot ID no annotation VI_04423 Bacilli_gi_167636592 Viruses.
p12646 no NCBI prot ID no annotation VI_00424 Bacilli_gi_423496617 Viruses.
p310995 no NCBI prot ID no annotation VI_04421 Bacilli_gi_165873068 Viruses.
p311329 no NCBI prot ID no annotation VI_04427 Bacilli_gi_177655428 Viruses.
p12747 no NCBI prot ID no annotation VI_00425 Bacilli_gi_423502290 Viruses.
p370358 no NCBI prot ID no annotation VI_05200 Bacilli_gi_564753172 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p35195 no NCBI prot ID no annotation VI_00711 Bacilli_gi_507055493_2793767_2856861 Viruses.
p53669 no NCBI prot ID no annotation VI_00422 Bacilli_gi_423490892 Viruses.
p71921 no NCBI prot ID no annotation VI_05747 Clostridia_gi_153883184 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Clostridium phage c-st.
p258444 no NCBI prot ID no annotation VI_05781 Clostridia_gi_485044592 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_13440 7 no annotation unknown function 7 0 1000
phrog_12246 8 no annotation unknown function 7 8.30E-35 25.2
phrog_16113 6 no annotation unknown function 6 0 1000
phrog_25713 3 no annotation unknown function 3 0 1000
phrog_27850 3 no annotation unknown function 3 0 1000
phrog_21622 4 no annotation unknown function 3 1.07E-17 8.09
phrog_23844 3 no annotation unknown function 3 0 1000
phrog_36497 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 90.7 0.048 5-46 / 6-46
phrog_1729 no annotation unknown function 94.9 0.0017 16-64 / 82-129
phrog_1969 no annotation unknown function 92.1 0.024 14-64 / 50-99
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.6 0.031 9-42 / 28-61
phrog_2474 MerR-like transcriptional regulator transcription regulation 93.4 0.01 15-66 / 12-64
phrog_2528 no annotation unknown function 93.3 0.011 6-68 / 13-79
phrog_2655 excisionase integration and excision 96.0 0.00015 15-56 / 4-48
phrog_2907 excisionase integration and excision 96.2 8.2E-05 15-63 / 2-54
phrog_38708 no annotation unknown function 98.8 2.5E-12 1-70 / 1-70
phrog_3 transcriptional repressor transcription regulation 91.5 0.034 8-43 / 6-40
phrog_409 transcriptional regulator transcription regulation 93.8 0.0069 5-48 / 1-37
phrog_4745 DNA binding protein DNA, RNA and nucleotide metabolism 94.8 0.0019 17-68 / 3-61
phrog_57 terminase small subunit head and packaging 95.8 0.0003 18-46 / 2-30
phrog_6401 DNA binding protein DNA, RNA and nucleotide metabolism 96.3 7.2E-05 17-69 / 8-60
phrog_6620 transposase integration and excision 95.5 0.00061 17-62 / 2-48
phrog_668 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.9 0.014 13-64 / 31-81
phrog_66 excisionase and transcriptional regulator integration and excision 97.6 1.1E-07 13-69 / 4-60
phrog_7338 no annotation unknown function 94.8 0.0021 14-67 / 26-78
phrog_7735 excisionase integration and excision 95.3 0.00092 18-64 / 17-63
phrog_8013 no annotation unknown function 90.9 0.045 12-65 / 170-223
phrog_9452 terminase small subunit head and packaging 92.9 0.014 15-72 / 2-58

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF11112.7 Pyocin activator protein PrtN 5.1E-11 25-80 / 9-70
PF06806.11 Putative excisionase (DUF1233) 7.3E-10 26-79 / 6-69
PF09035.9 Excisionase from transposon Tn916 4.4E-09 26-80 / 12-67
PF12964.6 Protein of unknown function (DUF3853) 5.9E-09 26-78 / 42-95
PF07618.10 Protein of unknown function (DUF1580) 2E-08 31-79 / 4-56
PF10743.8 Regulatory phage protein cox 3E-08 26-82 / 8-69
PF12728.6 Helix-turn-helix domain 6.2E-08 30-78 / 2-50
PF07825.10 Excisionase-like protein 8.7E-08 29-72 / 2-48
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 1.6E-07 29-75 / 3-51
PF07278.10 Protein of unknown function (DUF1441) 2.5E-07 30-80 / 2-51
PF13591.5 MerR HTH family regulatory protein 2.7E-07 30-75 / 1-45
PF07471.11 Phage DNA packaging protein Nu1 3.6E-07 29-81 / 2-58
PF13411.5 MerR HTH family regulatory protein 1.2E-06 30-75 / 1-47
PF17443.1 Uncharacterized protein pXO2-72 2.6E-06 27-54 / 6-33
PF00376.22 MerR family regulatory protein 4.6E-06 31-58 / 1-28
PF01381.21 Helix-turn-helix 9.3E-06 26-53 / 6-33
PF04936.11 Protein of unknown function (DUF658) 0.00083 28-57 / 87-116
PF06322.10 Phage NinH protein 2.6E-05 23-55 / 10-42
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 2.7E-05 17-53 / 11-47
PF08822.10 Protein of unknown function (DUF1804) 2.8E-05 12-52 / 2-42
PF09607.9 Brinker DNA-binding domain 3.2E-05 12-53 / 5-49
PF07750.10 GcrA cell cycle regulator 3.3E-05 12-55 / 2-45
PF10654.8 Protein of unknown function (DUF2481) 4.9E-05 27-53 / 78-104
PF01710.15 Transposase 5.8E-05 12-53 / 2-42
PF12824.6 Mitochondrial ribosomal protein subunit L20 5.8E-05 12-53 / 88-131
PF13309.5 HTH domain 8E-05 30-50 / 42-62
PF13413.5 Helix-turn-helix domain 9.1E-05 26-53 / 6-33
PF05339.10 Protein of unknown function (DUF739) 9.9E-05 25-54 / 12-41
PF06627.10 Protein of unknown function (DUF1153) 0.00012 12-52 / 29-69
PF08876.10 Domain of unknown function (DUF1836) 0.00013 29-74 / 10-61
PF10668.8 Phage terminase small subunit 0.00013 12-53 / 4-46
PF13011.5 leucine-zipper of insertion element IS481 0.00015 13-53 / 8-48
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00016 26-52 / 20-46
PF00292.17 'Paired box' domain 0.00016 12-52 / 17-56
PF16677.4 DNA-packaging protein gp3 0.00016 13-53 / 6-53
PF12116.7 Stage III sporulation protein D 0.00017 26-53 / 16-43
PF04645.11 Protein of unknown function, DUF603 0.0002 17-56 / 8-50
PF13744.5 Helix-turn-helix domain 0.00021 19-53 / 21-55
PF00356.20 Bacterial regulatory proteins, lacI family 0.00021 31-54 / 1-24
PF14590.5 Domain of unknown function (DUF4447) 0.00022 20-54 / 11-45
PF07141.10 Putative bacteriophage terminase small subunit 0.00022 18-53 / 21-55
PF13171.5 Protein of unknown function (DUF4004) 0.00023 29-78 / 2-57
PF12759.6 InsA C-terminal domain 0.00025 14-52 / 7-44
PF12844.6 Helix-turn-helix domain 0.00026 26-54 / 9-37
PF05344.10 Domain of Unknown Function (DUF746) 0.00026 27-53 / 10-36
PF02042.14 RWP-RK domain 0.00027 26-55 / 9-38
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0003 26-52 / 7-34
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.00032 28-54 / 12-38
PF08535.9 KorB domain 0.00033 28-54 / 2-28
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.00034 28-54 / 10-37
PF02954.18 Bacterial regulatory protein, Fis family 0.00036 27-51 / 14-38
PF07453.12 NUMOD1 domain 0.00036 28-49 / 18-39
PF04552.12 Sigma-54, DNA binding domain 0.00038 26-53 / 45-72
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.00045 28-53 / 18-43
PF05225.15 helix-turn-helix, Psq domain 0.00046 26-52 / 13-40
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00064 31-52 / 28-49
PF08765.10 Mor transcription activator family 0.00068 29-54 / 72-97
PF13412.5 Winged helix-turn-helix DNA-binding 0.00078 28-52 / 16-40
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00079 31-51 / 53-73
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00082 26-55 / 79-108
PF13404.5 AsnC-type helix-turn-helix domain 0.00088 27-51 / 15-39
PF08965.9 Domain of unknown function (DUF1870) 0.00095 22-54 / 7-41
PF01527.19 Transposase 0.00096 15-53 / 7-45
PF07037.10 Putative transcription regulator (DUF1323) 0.001 30-52 / 1-23
PF15978.4 Tn7-like transposition protein D 0.0013 15-52 / 189-226
PF06413.10 Neugrin 0.0013 11-53 / 9-53
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0014 27-52 / 21-46
PF02796.14 Helix-turn-helix domain of resolvase 0.0018 28-51 / 20-43
PF05269.10 Bacteriophage CII protein 0.0022 26-52 / 20-46
PF13936.5 Helix-turn-helix domain 0.0022 27-51 / 18-42
PF16701.4 Adenylate cyclase regulatory domain 0.0024 28-56 / 57-86
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0024 31-53 / 10-31
PF02650.13 WhiA C-terminal HTH domain 0.0024 25-52 / 50-79
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0027 28-52 / 11-35
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.0028 28-53 / 54-79
PF00440.22 Bacterial regulatory proteins, tetR family 0.0032 30-53 / 16-39
PF13560.5 Helix-turn-helix domain 0.0033 25-54 / 10-39
PF06971.12 Putative DNA-binding protein N-terminus 0.0033 29-50 / 27-48
PF13693.5 Winged helix-turn-helix DNA-binding 0.0035 25-52 / 11-38
PF08222.10 CodY helix-turn-helix domain 0.0035 28-52 / 3-27
PF07638.10 ECF sigma factor 0.0037 27-52 / 147-172
PF05331.10 Protein of unknown function (DUF742) 0.0038 28-52 / 52-76
PF13518.5 Helix-turn-helix domain 0.004 28-52 / 10-34
PF07506.10 RepB plasmid partitioning protein 0.004 27-53 / 19-45
PF14549.5 DNA-binding transcriptional regulator Cro 0.004 27-49 / 8-29
PF05043.12 Mga helix-turn-helix domain 0.0041 26-52 / 27-53
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0043 24-53 / 121-150
PF14493.5 Helix-turn-helix domain 0.0045 27-52 / 10-35
PF01371.18 Trp repressor protein 0.0048 26-54 / 45-73
PF13022.5 Helix-turn-helix of insertion element transposase 0.0058 29-53 / 25-49
PF08281.11 Sigma-70, region 4 0.0067 27-52 / 24-49
PF08667.9 BetR domain 0.0068 23-54 / 12-47
PF02376.14 CUT domain 0.0068 21-52 / 12-44
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0069 24-52 / 15-49
PF01022.19 Bacterial regulatory protein, arsR family 0.0073 28-52 / 15-39
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0082 26-52 / 15-41
PF00325.19 Bacterial regulatory proteins, crp family 0.0085 31-51 / 4-24
PF11427.7 Tc3 transposase 0.0086 28-52 / 19-43
PF13384.5 Homeodomain-like domain 0.0091 29-52 / 17-40

Annotations of the NCBI proteins of this PHROG


1:transcriptional regulator 1:helix turn helix domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0016987 sigma factor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0019069 viral capsid assembly

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