phrog_5131 is made of 26 protein sequences and is annotated as "thymidylate synthase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
364.69 480 356


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019487_p188 YP_007003445.1 dUMP hydroxymethylase NC_019487 Bacillus phage SP-10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; unclassified Spounavirinae.
NC_028983_p157 YP_009216155.1 hypothetical protein NC_028983 Bacillus phage Shanette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_028982_p155 YP_009215935.1 thymidylate synthase NC_028982 Bacillus phage JL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_025423_p86 YP_009099130.1 putative replication protein NC_025423 Bacillus phage CP-51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_023719_p311 YP_009015622.1 gp319 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_011421_p136 YP_002300412.1 gp29 NC_011421 Bacillus virus SPO1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
NC_022761_p138 YP_008770072.1 thymidylate synthase NC_022761 Bacillus phage CampHawk Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
KY368639_p133 APZ82373.1 thymidylate synthase KY368639 Bacillus phage vB_BsuM-Goe2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus; unclassified Okubovirus; Bacillus virus vB_BsuM-Goe2.
KC758116_p20 AGI11256.1 thymidylate synthase/dCMP hydroxymethylase KC758116 Pseudomonas phage LKO4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus; Pseudomonas virus LKO4.
KY000220_p16 APL99315.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase KY000220 Bordetella phage FP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vojvodinavirus; Bordetella virus FP1.
NC_028980_p53 YP_009215744.1 putative thymidylate synthase NC_028980 Pseudomonas phage PAE1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus.
NC_007809_p58 YP_001294566.1 hypothetical protein ORF058 NC_007809 Pseudomonas phage M6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus.
NC_010811_p230 YP_001950109.1 deoxyuridylate hydroxymethyltransferase NC_010811 Ralstonia phage phiRSL1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Mieseafarmvirus.
KY000221_p16 APL99395.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase KY000221 Bordetella phage CN1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vojvodinavirus; Bordetella virus CN1.
NC_010116_p17 YP_001595840.1 hypothetical protein NC_010116 Pseudomonas phage YuA Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus.
NC_028770_p51 YP_009196304.1 putative thymidylate synthase NC_028770 Pseudomonas phage PaMx11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Abidjanvirus.
NC_006938_p24 YP_223948.1 thymidylate synthase NC_006938 Phage phiJL001 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus.
NC_026594_p14 YP_009125117.1 putative thymidylate synthase NC_026594 Pseudomonas phage vB_PaeS_PAO1_Ab18 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Abidjanvirus.
KX198613_p45 ANO57413.1 thymidylate synthase KX198613 Pseudomonas phage AN14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus; unclassified Yuavirus.
KU356689_p14 AMD43374.1 deoxyuridylate hydroxymethyltransferase KU356689 Pseudomonas phage ZC01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Abidjanvirus; unclassified Abidjanvirus.
MF490239_p27 ASZ72325.1 deoxyuridylate hydroxymethyltransferase MF490239 Pseudomonas phage vB_PaeS_S218 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus; unclassified Yuavirus.
KX961385_p16 APL99076.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase KX961385 Bordetella virus LK3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vojvodinavirus; unclassified Vojvodinavirus.
KY000219_p16 APL99234.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase KY000219 Bordetella phage CN2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vojvodinavirus; Bordetella virus CN2.
NC_029061_p16 YP_009222566.1 thymidylate synthase NC_029061 Rhodoferax phage P26218 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
NC_018282_p16 YP_006561023.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase NC_018282 Pseudomonas phage MP1412 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yuavirus.
KY000218_p17 APL99155.1 thymidylate synthase/deoxyuridylate hydroxymethyltransferase KY000218 Bordetella phage MW2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vojvodinavirus; Bordetella virus MW2.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_6047 20 no annotation unknown function 17 2.26E-76 66.77
phrog_1965 77 no annotation unknown function 9 1.45E-31 21.96
phrog_15783 6 head decoration head and packaging 6 0 1000
phrog_19970 4 no annotation unknown function 4 0 1000
phrog_2396 62 no annotation unknown function 4 3.08E-15 5.63
phrog_26771 3 no annotation unknown function 3 0 1000
phrog_1238 121 phosphoheptose isomerase moron, auxiliary metabolic gene and host takeover 3 7.73E-11 1.23

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_160 thymidylate synthase DNA, RNA and nucleotide metabolism 100.0 1.3E-34 7-229 / 2-233
phrog_3676 thymidylate synthase DNA, RNA and nucleotide metabolism 100.0 6.6E-53 1-225 / 1-236
phrog_5682 thymidylate synthase DNA, RNA and nucleotide metabolism 90.4 0.055 183-231 / 4-52

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00303.18 Thymidylate synthase 5.9E-39 53-273 / 1-222

Annotations of the NCBI proteins of this PHROG


10:thymidylate synthase 6:thymidylate synthase/deoxyuridylate hydroxymethyltransferase 3:hypothetical protein 2:dUMP hydroxymethylase 2:deoxyuridylate hydroxymethyltransferase 1:protein of an unannotated phage 1:replication protein 1:thymidylate synthase/dCMP hydroxymethylase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00560 thyA, TYMS : thymidylate synthase [EC:2.1.1.45] ko00240 Pyrimidine metabolism
ko00670 One carbon pool by folate
156 26

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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