phrog_5301 is made of 24 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
136.04 185 139


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p166315 no NCBI prot ID no annotation VI_04146 Actinobacteria_gi_550255506 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Rhodococcus phage REQ3.
NC_016654_p4 YP_005087196.1 hypothetical protein NC_016654 Rhodococcus phage REQ3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF155936_p34 ASJ79115.1 immunity repressor MF155936 Mycobacterium phage ZenTime222 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bernalvirus; unclassified Bernalvirus.
MG925349_p33 AVJ50250.1 immunity repressor MG925349 Mycobacterium phage Mendokysei Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bernalvirus; unclassified Bernalvirus.
NC_024135_p34 YP_009031161.1 immunity repressor NC_024135 Mycobacterium phage Bernal13 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bernalvirus.
KM591905_p34 AIT13447.1 immunity repressor KM591905 Mycobacterium phage RonRayGun Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bernalvirus; unclassified Bernalvirus.
MF668284_p90 ASZ74166.1 hypothetical protein MF668284 Mycobacterium phage Squint Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_004688_p98 NP_818399.1 gp100 NC_004688 Mycobacterium virus Omega Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_022067_p100 YP_008410489.1 immunity repressor NC_022067 Mycobacterium phage Wanda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_028876_p91 YP_009205221.1 hypothetical protein NC_028876 Mycobacterium phage Ariel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919512_p97 ATN89810.1 HTH DNA binding domain protein MF919512 Mycobacterium phage Klein Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919504_p98 ATN88905.1 hypothetical protein MF919504 Mycobacterium phage DmpstrDiver Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
JF937090_p98 AEK08155.1 hypothetical protein JF937090 Mycobacterium virus Baka Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF133445_p89 ASD53482.1 hypothetical protein MF133445 Mycobacterium phage Lucky2013 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919534_p89 ATS92931.1 hypothetical protein MF919534 Mycobacterium phage Superphikiman Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_026584_p96 YP_009124049.1 hypothetical protein NC_026584 Mycobacterium phage Minerva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_023690_p87 YP_009011986.1 gp87 NC_023690 Mycobacterium virus Courthouse Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF072690_p90 ASD50720.1 hypothetical protein MF072690 Mycobacterium phage Porcelain Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
JF937101_p95 AEK09476.1 hypothetical protein JF937101 Mycobacterium virus Littlee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_022066_p88 YP_008410246.1 immunity repressor NC_022066 Mycobacterium phage Redno2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
JF957059_p90 AEJ92284.1 hypothetical protein JF957059 Mycobacterium virus Optimus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_023738_p81 YP_009018092.1 gp81 NC_023738 Mycobacterium phage Thibault Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_028953_p92 YP_009213309.1 hypothetical protein NC_028953 Mycobacterium phage MiaZeal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
p32133 no NCBI prot ID no annotation VI_04105 Actinobacteria_gi_418422484 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Mycobacterium phage Dori.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_950 155 no annotation unknown function 17 1.21E-66 57.04

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13326 no annotation unknown function 92.3 0.021 8-67 / 6-59
phrog_1373 transcriptional regulator transcription regulation 96.6 2.3E-05 19-67 / 40-86
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 91.1 0.04 22-67 / 22-65
phrog_151 transposase integration and excision 93.7 0.0072 21-49 / 21-49
phrog_1558 no annotation unknown function 91.1 0.041 23-47 / 117-141
phrog_16278 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.0 9.4E-09 6-114 / 4-99
phrog_1702 transcriptional repressor transcription regulation 92.1 0.024 8-67 / 12-71
phrog_1746 transcriptional repressor transcription regulation 94.4 0.0033 25-87 / 24-82
phrog_18342 transcriptional repressor transcription regulation 94.1 0.0051 20-67 / 27-74
phrog_18815 no annotation unknown function 96.6 2.6E-05 6-121 / 3-107
phrog_19097 transcriptional repressor transcription regulation 97.6 1.6E-07 24-117 / 19-107
phrog_19579 transcriptional regulator transcription regulation 99.6 2.6E-20 8-115 / 4-103
phrog_2328 transcriptional repressor transcription regulation 95.1 0.0012 18-73 / 23-76
phrog_2439 transcriptional regulator transcription regulation 95.0 0.0014 19-67 / 15-61
phrog_2538 terminase small subunit head and packaging 96.2 9.1E-05 21-49 / 17-45
phrog_2907 excisionase integration and excision 90.4 0.054 24-49 / 6-31
phrog_2967 transcriptional regulator transcription regulation 95.2 0.001 20-79 / 18-72
phrog_3037 transcriptional repressor transcription regulation 92.4 0.02 15-115 / 19-113
phrog_309 terminase small subunit head and packaging 95.6 0.00047 20-46 / 21-47
phrog_35 transcriptional repressor transcription regulation 90.5 0.054 24-62 / 14-50
phrog_3949 transcriptional repressor transcription regulation 99.4 5.8E-17 6-116 / 16-117
phrog_3 transcriptional repressor transcription regulation 96.5 3.4E-05 20-67 / 13-58
phrog_4044 terminase small subunit head and packaging 91.3 0.038 17-49 / 24-56
phrog_409 transcriptional regulator transcription regulation 90.5 0.053 25-45 / 12-32
phrog_4102 terminase small subunit head and packaging 91.6 0.032 18-49 / 21-52
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 95.4 0.00069 22-95 / 19-92
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.7 1.5E-05 19-77 / 14-68
phrog_4494 no annotation unknown function 91.5 0.033 18-81 / 12-101
phrog_4779 transcriptional regulator transcription regulation 92.2 0.023 21-47 / 12-38
phrog_4836 CII-like regulator transcription regulation 90.8 0.047 6-67 / 80-137
phrog_4 transcriptional repressor transcription regulation 95.2 0.001 21-79 / 12-64
phrog_534 DNA binding protein DNA, RNA and nucleotide metabolism 92.6 0.018 24-47 / 26-49
phrog_5823 transcriptional regulator transcription regulation 91.5 0.033 19-67 / 13-60
phrog_6223 transcriptional repressor transcription regulation 96.3 6E-05 6-60 / 4-53
phrog_638 transcriptional regulator transcription regulation 96.3 6.4E-05 16-81 / 6-70
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.012 19-50 / 15-46
phrog_66 excisionase and transcriptional regulator integration and excision 95.7 0.00037 21-49 / 7-35
phrog_6831 transcriptional regulator transcription regulation 92.9 0.014 9-65 / 4-57
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.9 0.0018 11-46 / 32-67
phrog_7241 transcriptional regulator transcription regulation 91.1 0.04 21-67 / 72-116
phrog_7344 terminase small subunit head and packaging 92.7 0.017 22-49 / 25-52
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 93.6 0.0081 20-49 / 15-44
phrog_7676 no annotation unknown function 95.7 0.00037 19-51 / 12-44
phrog_769 transcriptional repressor transcription regulation 91.6 0.033 6-67 / 9-64
phrog_8 transcriptional regulator transcription regulation 97.0 4.4E-06 22-67 / 13-54

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 6.1E-09 28-96 / 7-78
PF13744.5 Helix-turn-helix domain 1.2E-07 30-94 / 17-79
PF01381.21 Helix-turn-helix 2E-07 40-92 / 4-54
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 2.3E-07 36-97 / 3-61
PF14590.5 Domain of unknown function (DUF4447) 3.5E-07 31-96 / 7-72
PF05339.10 Protein of unknown function (DUF739) 3.9E-07 34-94 / 6-63
PF13413.5 Helix-turn-helix domain 4.1E-07 40-91 / 4-59
PF13443.5 Cro/C1-type HTH DNA-binding domain 4.6E-07 40-96 / 5-62
PF12844.6 Helix-turn-helix domain 5.8E-07 40-95 / 7-60
PF04645.11 Protein of unknown function, DUF603 7.3E-07 29-84 / 5-60
PF13560.5 Helix-turn-helix domain 1.4E-06 32-93 / 2-63
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.7E-06 32-94 / 70-128
PF08667.9 BetR domain 3.2E-06 31-97 / 5-72
PF05269.10 Bacteriophage CII protein 4.4E-06 40-97 / 18-71
PF08965.9 Domain of unknown function (DUF1870) 8.1E-06 33-94 / 3-66
PF14549.5 DNA-binding transcriptional regulator Cro 3.2E-05 40-93 / 5-52
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 3.6E-05 40-96 / 4-57
PF13693.5 Winged helix-turn-helix DNA-binding 3.8E-05 36-96 / 7-61
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 7.3E-05 32-86 / 114-165
PF00157.16 Pou domain - N-terminal to homeobox domain 8.3E-05 30-87 / 6-64
PF12116.7 Stage III sporulation protein D 9.3E-05 43-89 / 17-62
PF10654.8 Protein of unknown function (DUF2481) 0.00017 41-70 / 76-105
PF02376.14 CUT domain 0.00025 30-95 / 6-67
PF00356.20 Bacterial regulatory proteins, lacI family 0.00026 47-79 / 1-31
PF08535.9 KorB domain 0.004 44-70 / 2-28

Annotations of the NCBI proteins of this PHROG


15:hypothetical protein 6:immunity repressor 1:HTH DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0005634 nucleus
GO:0045893 positive regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding

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