phrog_5399 is made of 24 protein sequences and is annotated as "SAM-dependent methyltransferase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
152.96 168 149


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_022763_p192 YP_008770416.1 S-adenosylmethionine-dependent methyltransferase NC_022763 Bacillus phage Spock Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.
NC_020873_p153 YP_007677051.1 putative methyltransferase NC_020873 Bacillus phage vB_BceM_Bc431v3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus.
JN797798_p133 AEW47639.1 putative methyltransferase type 11 JN797798 Bacillus phage BCU4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Tsarbombavirus; Bacillus virus BCP78.
KT070867_p47 AKQ08362.1 putative methyltransferase type 11 KT070867 Bacillus phage PBC2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_028890_p136 YP_009206971.1 methyltransferase NC_028890 Bacillus phage TsarBomba Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Tsarbombavirus.
KU737345_p197 AMW61652.1 methyltransferase KU737345 Bacillus phage Juglone Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus; Bacillus virus Troll; Bacillus phage Troll.
NC_027355_p155 YP_009149716.1 putative methyltransferase NC_027355 Bacillus phage BCP8-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus.
KT995480_p148 ALO79569.1 S-adenosylmethionine-dependent methyltransferase KT995480 Bacillus phage BM10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
KT187252_p134 ALA07728.1 putative methyltransferase domain-containing protein KT187252 Bacillus phage PBC6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Tsarbombavirus; unclassified Tsarbombavirus.
NC_031100_p192 YP_009290071.1 methyltransferase NC_031100 Bacillus phage Phrodo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus; unclassified Bequatrovirus.
KX961630_p158 AOZ62079.1 hypothetical protein KX961630 Bacillus phage QCM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Tsarbombavirus; unclassified Tsarbombavirus.
NC_027352_p119 YP_009149157.1 putative methyltransferase NC_027352 Bacillus phage JBP901 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus.
KX495186_p152 ANY29354.1 putative methyltransferase KX495186 Bacillus phage PK16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus; unclassified Caeruleovirus.
NC_024788_p193 YP_009055958.1 methyltransferase NC_024788 Bacillus phage Riley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.
KY888882_p196 ARQ95184.1 methyltransferase KY888882 Bacillus phage Flapjack Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus; unclassified Bequatrovirus.
NC_022088_p201 YP_008430985.1 methyltransferase NC_022088 Bacillus phage Troll Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.
MF765814_p193 ASZ75926.1 methyltransferase MF765814 Bacillus phage Taffo16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus; unclassified Bequatrovirus.
NC_024137_p155 YP_009031436.1 putative methyltransferase NC_024137 Bacillus phage Bcp1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus.
NC_031056_p124 YP_009285436.1 hypothetical protein NC_031056 Bacillus phage Deep Blue Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Caeruleovirus.
NC_018860_p143 YP_006907978.1 hypothetical protein NC_018860 Bacillus phage BCP78 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Tsarbombavirus.
NC_023007_p63 YP_008873305.1 hypothetical protein NC_023007 Bacillus phage vB_BanS-Tsamsa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_022769_p193 YP_008771220.1 S-adenosylmethionine-dependent methyltransferase NC_022769 Bacillus phage BigBertha Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.
NC_018863_p151 YP_006908380.1 putative methyltransferase type 11 NC_018863 Bacillus phage B4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.
NC_028887_p200 YP_009206555.1 methyltransferase NC_028887 Bacillus phage AvesoBmore Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bequatrovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8617 13 no annotation unknown function 10 2.24E-46 36.77
phrog_10308 10 no annotation unknown function 10 0 1000
phrog_14898 6 no annotation unknown function 6 0 1000
phrog_19087 4 no annotation unknown function 4 0 1000
phrog_24338 3 no annotation unknown function 3 0 1000
phrog_18229 5 no annotation unknown function 2 1.42E-12 2.97
phrog_31859 2 no annotation unknown function 2 0 1000
phrog_9059 12 no annotation unknown function 2 3.13E-11 1.63

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_22502 methyltransferase other 96.7 1.6E-05 10-85 / 108-179
phrog_24759 methyltransferase other 91.4 0.036 3-89 / 61-161
phrog_24903 no annotation unknown function 94.6 0.0027 26-80 / 196-246
phrog_4752 tRNA methyltransferase other 94.7 0.0022 38-88 / 118-168

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05219.11 DREV methyltransferase 1.1E-10 1-135 / 93-237
PF00891.17 O-methyltransferase 1.3E-10 42-131 / 140-225
PF01209.17 ubiE/COQ5 methyltransferase family 1.9E-10 41-135 / 134-238
PF05891.11 AdoMet dependent proline di-methyltransferase 1.9E-10 1-133 / 58-195
PF02390.16 Putative methyltransferase 2.3E-10 40-131 / 78-179
PF08003.10 Protein of unknown function (DUF1698) 2.8E-10 40-132 / 181-265
PF03492.14 SAM dependent carboxyl methyltransferase 3E-10 39-84 / 106-182
PF06080.11 Protein of unknown function (DUF938) 3.4E-10 40-132 / 100-189
PF13489.5 Methyltransferase domain 3.6E-10 42-131 / 104-185
PF07942.11 N2227-like protein 4.3E-10 40-134 / 163-239
PF12147.7 Putative methyltransferase 5E-10 40-132 / 202-289
PF01234.16 NNMT/PNMT/TEMT family 8.7E-10 40-134 / 155-237
PF13847.5 Methyltransferase domain 1.8E-09 1-83 / 6-120
PF07021.11 Methionine biosynthesis protein MetW 1.9E-09 1-134 / 16-165
PF05175.13 Methyltransferase small domain 2.7E-09 1-84 / 34-141
PF03291.15 mRNA capping enzyme 2.8E-09 40-85 / 131-178
PF05724.10 Thiopurine S-methyltransferase (TPMT) 3E-09 41-84 / 121-164
PF02353.19 Mycolic acid cyclopropane synthetase 3.3E-09 1-131 / 64-202
PF05401.10 Nodulation protein S (NodS) 3.8E-09 1-133 / 46-178
PF07091.10 Ribosomal RNA methyltransferase (FmrO) 4.3E-09 1-131 / 105-237
PF05971.11 Protein of unknown function (DUF890) 4.3E-09 40-135 / 176-291
PF10017.8 Histidine-specific methyltransferase, SAM-dependent 4.7E-09 41-83 / 135-177
PF11968.7 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 4.9E-09 1-131 / 55-180
PF03141.15 Putative S-adenosyl-L-methionine-dependent methyltransferase 5.9E-09 1-83 / 357-464
PF05148.14 Hypothetical methyltransferase 1.3E-08 1-81 / 75-158
PF01739.17 CheR methyltransferase, SAM binding domain 1.5E-08 40-84 / 133-177
PF04672.11 S-adenosyl methyltransferase 2.7E-08 40-132 / 141-231
PF08123.12 Histone methylation protein DOT1 2.8E-08 41-131 / 122-186
PF01269.16 Fibrillarin 5.4E-08 41-133 / 141-209
PF16803.4 Fe-S cluster assembly protein DRE2 N-terminus 6.6E-08 1-83 / 1-90
PF03848.13 Tellurite resistance protein TehB 9.7E-08 40-84 / 93-137
PF03269.13 Caenorhabditis protein of unknown function, DUF268 1.6E-07 1-131 / 3-140
PF12692.6 S-adenosyl-L-methionine methyltransferase 1.7E-07 1-84 / 31-135
PF04378.12 Ribosomal RNA large subunit methyltransferase D, RlmJ 3.5E-07 1-84 / 63-170
PF03602.14 Conserved hypothetical protein 95 4.1E-07 40-84 / 102-144
PF12847.6 Methyltransferase domain 4.4E-07 41-80 / 81-116
PF02527.14 rRNA small subunit methyltransferase G 4.9E-07 40-84 / 114-152
PF01564.16 Spermine/spermidine synthase domain 4.9E-07 40-83 / 89-134
PF08241.11 Methyltransferase domain 5.7E-07 40-78 / 59-95
PF11599.7 RRNA methyltransferase AviRa 6E-07 40-84 / 156-205
PF05185.15 PRMT5 arginine-N-methyltransferase 6.1E-07 40-78 / 132-170
PF06859.11 Bicoid-interacting protein 3 (Bin3) 8.2E-07 43-133 / 1-90
PF10672.8 S-adenosylmethionine-dependent methyltransferase 1.2E-06 1-83 / 126-240
PF10294.8 Lysine methyltransferase 1.2E-06 40-84 / 115-157
PF04816.11 tRNA (adenine(22)-N(1))-methyltransferase 2E-06 41-83 / 65-103
PF09243.9 Mitochondrial small ribosomal subunit Rsm22 2.2E-06 40-73 / 101-134
PF06325.12 Ribosomal protein L11 methyltransferase (PrmA) 2.6E-06 41-81 / 237-272
PF11312.7 Putative SAM-dependent methyltransferase 3.2E-06 40-84 / 245-293
PF03059.15 Nicotianamine synthase protein 4.1E-06 40-84 / 191-234
PF06460.11 Coronavirus NSP13 4.3E-06 40-84 / 120-173
PF08242.11 Methyltransferase domain 4.4E-06 42-77 / 67-101
PF01861.15 Protein of unknown function DUF43 4.7E-06 40-83 / 109-149
PF03686.12 Uncharacterised protein family (UPF0146) 5.1E-06 1-85 / 17-104
PF13679.5 Methyltransferase domain 7.2E-06 40-83 / 100-136
PF01728.18 FtsJ-like methyltransferase 1.3E-05 42-83 / 93-143
PF01189.16 16S rRNA methyltransferase RsmB/F 1.3E-05 61-83 / 118-140
PF02005.15 N2,N2-dimethylguanosine tRNA methyltransferase 1.5E-05 41-84 / 173-210
PF04989.11 Cephalosporin hydroxylase 1.8E-05 41-84 / 125-165
PF01596.16 O-methyltransferase 2.5E-05 41-85 / 121-160
PF02475.15 Met-10+ like-protein 3.3E-05 41-78 / 169-200
PF08468.10 Methyltransferase small domain N-terminal 3.9E-05 2-84 / 15-107
PF05711.10 Macrocin-O-methyltransferase (TylF) 4E-05 41-83 / 200-238
PF08704.9 tRNA methyltransferase complex GCD14 subunit 4E-05 41-83 / 114-149
PF13649.5 Methyltransferase domain 4.3E-05 2-17 / 1-16
PF02636.16 Putative S-adenosyl-L-methionine-dependent methyltransferase 4.6E-05 64-82 / 114-133
PF01135.18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5.2E-05 41-83 / 144-178
PF14314.5 Virus-capping methyltransferase 5.9E-05 40-83 / 428-472
PF09445.9 RNA cap guanine-N2 methyltransferase 6E-05 1-18 / 3-20
PF04445.12 Putative SAM-dependent methyltransferase 6.4E-05 42-73 / 138-166
PF13578.5 Methyltransferase domain 8E-05 41-80 / 79-115
PF01795.18 MraW methylase family 8.3E-05 1-18 / 23-40
PF07279.10 Protein of unknown function (DUF1442) 0.00018 41-83 / 112-148
PF05958.10 tRNA (Uracil-5-)-methyltransferase 0.00019 1-19 / 203-221
PF00398.19 Ribosomal RNA adenine dimethylase 0.00051 1-19 / 33-51
PF05430.10 S-adenosyl-L-methionine-dependent methyltransferase 0.00053 25-82 / 32-90
PF07757.12 Predicted AdoMet-dependent methyltransferase 0.0013 1-17 / 62-78
PF04072.13 Leucine carboxyl methyltransferase 0.0053 1-18 / 84-101

Annotations of the NCBI proteins of this PHROG


13:methyltransferase 3:hypothetical protein 3:S-adenosylmethionine-dependent methyltransferase 3:methyltransferase type 11 1:protein of an unannotated phage 1:methyltransferase domain-containing protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005737 cytoplasm
GO:0008168 methyltransferase activity
GO:0006412 translation
GO:0006396 RNA processing
GO:0031167 rRNA methylation
GO:0016429 tRNA (adenine-N1-)-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0009452 7-methylguanosine RNA capping
GO:0030488 tRNA methylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0009877 nodulation
GO:0032259 methylation
GO:0001510 RNA methylation
GO:0008171 O-methyltransferase activity
GO:0003723 RNA binding
GO:0006480 N-terminal protein amino acid methylation
GO:0008152 metabolic process
GO:0030418 nicotianamine biosynthetic process
GO:0008033 tRNA processing
GO:0030410 nicotianamine synthase activity
GO:0008990 rRNA (guanine-N2-)-methyltransferase activity
GO:0006364 rRNA processing
GO:0005730 nucleolus
GO:0031515 tRNA (m1A) methyltransferase complex
GO:0008610 lipid biosynthetic process
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0055114 oxidation-reduction process
GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
GO:0008649 rRNA methyltransferase activity
GO:0070475 rRNA base methylation
GO:0009312 oligosaccharide biosynthetic process

Loading in process