phrog_5484 is made of 24 protein sequences and is annotated as "DnaA-like replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
245.33 388 238


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_005361_p6 NP_963972.1 NTP-binding motif containing protein NC_005361 Sulfolobus virus Kamchatka 1 Viruses; Fuselloviridae; Alphafusellovirus.
NC_009986_p12 YP_001552190.1 hypothetical protein NC_009986 Sulfolobus spindle-shaped virus 4 (SSV4) Viruses; Fuselloviridae; Alphafusellovirus.
NC_013585_p7 YP_003331412.1 DnaA-like protein NC_013585 Acidianus spindle-shaped virus 1 (SSV1) Viruses; Fuselloviridae; Betafusellovirus.
p388676 no NCBI prot ID no annotation VI_04039 Thermoprotei_gi_227829020_118353_133781 Viruses; Fuselloviridae.
p442949 no NCBI prot ID no annotation VI_12476 Thermoprotei_gi_254499611 Viruses; Fuselloviridae; Alphafusellovirus.
NC_001338_p1 NP_039777.1 ORF B-251 NC_001338 Sulfolobus spindle-shaped virus 1 Viruses; Fuselloviridae; Alphafusellovirus.
NC_013588_p6 YP_003331489.1 DnaA-like protein NC_013588 Sulfolobus spindle-shaped virus 7 (SSV7) Viruses; Fuselloviridae; Alphafusellovirus.
p370722 no NCBI prot ID no annotation VI_04038 Thermoprotei_gi_374633285_291125_308527 Viruses; Fuselloviridae; Alphafusellovirus.
KY563228_p7 AQQ16827.1 C250 KY563228 Sulfolobus spindle-shaped virus Lassen Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
p417107 no NCBI prot ID no annotation VI_04041 Thermoprotei_gi_229577818_1585865_1598038 Viruses; Fuselloviridae.
NC_005360_p6 NP_963931.1 NTP-binding motif containing protein NC_005360 Sulfolobus virus Ragged Hills Viruses; Fuselloviridae; Alphafusellovirus.
NC_011217_p12 YP_002221477.1 hypothetical protein NC_011217 Sulfolobus spindle-shaped virus 5 (SSV5) Viruses; Fuselloviridae; Alphafusellovirus.
NC_005265_p3 NP_944455.1 NTP-binding motif containing protein NC_005265 Sulfolobus spindle-shaped virus 2 Viruses; Fuselloviridae; Alphafusellovirus.
NC_013587_p7 YP_003331457.1 DnaA-like protein NC_013587 Sulfolobus spindle-shaped virus 6 (SSV6) Viruses; Fuselloviridae; Betafusellovirus.
KY579375_p5 AQQ16864.1 ORF9 KY579375 Sulfolobus spindle-shaped virus 3 Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
p120272 no NCBI prot ID no annotation VI_12478 Thermoprotei_gi_483377487_338515_381935 Viruses; Fuselloviridae; Alphafusellovirus.
p120329 no NCBI prot ID no annotation VI_12480 Thermoprotei_gi_483378806_339141_382559 Viruses; Fuselloviridae; Alphafusellovirus.
p395689 no NCBI prot ID no annotation VI_04040 Thermoprotei_gi_227826411_1679190_1693805 Viruses; Fuselloviridae.
NC_028256_p19 YP_009177670.1 hypothetical protein NC_028256 Aeropyrum pernix ovoid virus 1 Viruses; Guttaviridae; Betaguttavirus.
NC_028992_p37 YP_009216743.1 hypothetical protein NC_028992 Sulfolobales Virus YNP2 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
NC_029027_p50 YP_009219949.1 hypothetical protein NC_029027 Sulfolobales virus YNP1 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
NC_020882_p8 YP_007678010.1 DnaA-like protein NC_020882 Sulfolobales Mexican fusellovirus 1 (SMF1) Viruses; Fuselloviridae; unclassified Fuselloviridae.
NC_028268_p12 YP_009177742.1 hypothetical protein NC_028268 Aeropyrum pernix spindle-shaped virus 1 Viruses; unclassified viruses; unclassified archaeal viruses.
NC_007914_p16 YP_529528.1 hypothetical protein NC_007914 His 1 virus Viruses; Halspiviridae; Salterprovirus; Salterprovirus His1.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_6627 18 no annotation unknown function 18 0 1000
phrog_19807 4 no annotation unknown function 2 1.34E-13 4.0
phrog_31845 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10401 ATPase other 90.9 0.044 21-144 / 198-315
phrog_11254 DnaA-like replication initiation protein DNA, RNA and nucleotide metabolism 99.5 1.6E-17 25-219 / 84-290
phrog_11838 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 95.5 0.00061 24-63 / 37-76
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.9 0.00021 24-103 / 11-89
phrog_1313 DNA helicase DNA, RNA and nucleotide metabolism 92.2 0.022 10-78 / 159-230
phrog_1366 no annotation unknown function 94.3 0.004 20-102 / 7-99
phrog_14322 no annotation unknown function 95.9 0.00025 18-144 / 185-302
phrog_14685 no annotation unknown function 96.1 0.00012 28-49 / 3-24
phrog_1675 morphogenesis (protein I of M13) head and packaging 91.2 0.04 30-148 / 4-137
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 96.5 3E-05 25-160 / 36-158
phrog_170 PhoH-like phosphate starvation-inducible other 90.3 0.056 27-52 / 50-75
phrog_1979 no annotation unknown function 90.9 0.044 22-151 / 121-266
phrog_197 Zot-like toxin moron, auxiliary metabolic gene and host takeover 94.9 0.0017 31-160 / 5-146
phrog_2071 ATPase other 95.3 0.00087 30-49 / 6-25
phrog_22963 no annotation unknown function 91.6 0.032 25-50 / 33-58
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 90.9 0.045 28-50 / 36-58
phrog_2666 terminase large subunit head and packaging 91.8 0.029 92-154 / 114-173
phrog_27475 no annotation unknown function 91.9 0.027 18-139 / 429-546
phrog_2872 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 91.8 0.028 28-145 / 3-129
phrog_296 DNA transposition protein integration and excision 94.7 0.0023 29-141 / 93-203
phrog_3757 no annotation unknown function 90.8 0.047 27-56 / 126-155
phrog_38691 no annotation unknown function 91.1 0.04 14-163 / 13-156
phrog_4581 terminase small subunit head and packaging 95.0 0.0015 27-154 / 121-217
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 98.1 4.9E-09 11-145 / 95-224
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 96.4 5.1E-05 27-149 / 38-166
phrog_6891 ATPase other 95.9 0.00023 29-157 / 36-174
phrog_7485 no annotation unknown function 96.0 0.00016 29-152 / 229-353
phrog_761 thymidylate kinase other 90.1 0.062 29-54 / 4-29
phrog_7998 no annotation unknown function 92.1 0.024 10-45 / 23-56
phrog_9172 no annotation unknown function 95.2 0.00097 25-136 / 95-212

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00308.17 Bacterial dnaA protein 7.1E-11 61-86 / 33-58
PF05673.12 Protein of unknown function (DUF815) 8.3E-10 40-86 / 33-79
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 1.2E-09 40-86 / 23-70
PF06068.12 TIP49 C-terminus 3.5E-09 40-86 / 28-75
PF07693.13 KAP family P-loop domain 3.7E-09 59-86 / 29-56
PF01637.17 ATPase domain predominantly from Archaea 6.4E-09 41-86 / 4-45
PF10443.8 RNA12 protein 1.3E-08 235-263 / 249-277
PF09820.8 Predicted AAA-ATPase 3.2E-08 61-86 / 31-56
PF05621.10 Bacterial TniB protein 4.1E-08 62-85 / 39-62
PF10923.7 P-loop Domain of unknown function (DUF2791) 5E-08 40-86 / 29-74
PF12775.6 P-loop containing dynein motor region D3 1.1E-07 60-87 / 32-59
PF14516.5 AAA-like domain 1.8E-07 60-86 / 29-55
PF00158.25 Sigma-54 interaction domain 4.1E-07 42-86 / 5-47
PF00931.21 NB-ARC domain 5.1E-07 60-85 / 19-44
PF04665.11 Poxvirus A32 protein 8.2E-07 60-86 / 12-38
PF13173.5 AAA domain 9.9E-07 61-84 / 2-25
PF03969.15 AFG1-like ATPase 1E-06 60-86 / 66-92
PF14532.5 Sigma-54 interaction domain 1.7E-06 60-86 / 20-46
PF07726.10 ATPase family associated with various cellular activities (AAA) 2.3E-06 63-86 / 1-24
PF03215.14 Rad17 cell cycle checkpoint protein 2.5E-06 44-86 / 27-70
PF13191.5 AAA ATPase domain 3.4E-06 40-86 / 4-49
PF05729.11 NACHT domain 5E-06 63-86 / 2-25
PF13401.5 AAA domain 7.1E-06 61-86 / 5-30
PF06431.10 Polyomavirus large T antigen C-terminus 7.5E-06 60-87 / 154-181
PF07728.13 AAA domain (dynein-related subfamily) 8.4E-06 64-86 / 2-24
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 9.5E-06 61-86 / 4-29
PF00004.28 ATPase family associated with various cellular activities (AAA) 1.4E-05 64-86 / 1-23
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 1.6E-05 61-87 / 32-58
PF01078.20 Magnesium chelatase, subunit ChlI 1.9E-05 61-86 / 22-47
PF00493.22 MCM2/3/5 family 2.1E-05 61-87 / 57-83
PF00519.16 Papillomavirus helicase 2.1E-05 60-86 / 261-287
PF06144.12 DNA polymerase III, delta subunit 2.3E-05 224-260 / 141-177
PF01695.16 IstB-like ATP binding protein 2.3E-05 60-86 / 47-73
PF13337.5 Putative ATP-dependent Lon protease 2.6E-05 60-86 / 205-231
PF04851.14 Type III restriction enzyme, res subunit 2.8E-05 60-86 / 22-48
PF07724.13 AAA domain (Cdc48 subfamily) 2.9E-05 61-85 / 3-27
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 3.4E-05 63-86 / 2-25
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 5.4E-05 64-84 / 1-21
PF12780.6 P-loop containing dynein motor region D4 6.9E-05 60-87 / 30-57
PF09848.8 Uncharacterized conserved protein (DUF2075) 9.8E-05 62-85 / 2-25
PF08298.10 PrkA AAA domain 0.0001 60-86 / 84-110
PF05707.11 Zonular occludens toxin (Zot) 0.00013 63-81 / 2-20
PF05970.13 PIF1-like helicase 0.00015 60-87 / 21-48
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.00017 59-87 / 26-54
PF00625.20 Guanylate kinase 0.00017 61-86 / 2-27
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.00017 62-86 / 2-26
PF13177.5 DNA polymerase III, delta subunit 0.00028 61-86 / 19-44
PF13671.5 AAA domain 0.00031 64-86 / 2-24
PF13521.5 AAA domain 0.00032 64-85 / 2-23
PF00910.21 RNA helicase 0.00036 64-86 / 1-23
PF06414.11 Zeta toxin 0.00037 60-85 / 13-38
PF10649.8 Protein of unknown function (DUF2478) 0.00037 64-87 / 1-24
PF06745.12 KaiC 0.0004 60-85 / 18-43
PF03266.14 NTPase 0.00041 64-85 / 2-23
PF01745.15 Isopentenyl transferase 0.00043 62-86 / 2-26
PF13238.5 AAA domain 0.00043 64-86 / 1-23
PF05127.13 Helicase 0.00064 65-86 / 1-22
PF01591.17 6-phosphofructo-2-kinase 0.00066 60-86 / 8-34
PF05272.10 Virulence-associated protein E 0.00067 60-85 / 58-83
PF13189.5 Cytidylate kinase-like family 0.0007 63-86 / 1-24
PF01712.18 Deoxynucleoside kinase 0.00074 64-86 / 1-23
PF08433.9 Chromatin associated protein KTI12 0.00077 62-86 / 2-26
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.00081 60-86 / 13-39
PF08303.10 tRNA ligase kinase domain 0.00084 63-86 / 1-24
PF01121.19 Dephospho-CoA kinase 0.00097 63-86 / 2-25
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0012 63-86 / 1-24
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0013 60-86 / 23-49
PF02223.16 Thymidylate kinase 0.0014 66-87 / 1-22
PF01443.17 Viral (Superfamily 1) RNA helicase 0.0014 64-84 / 1-20
PF02224.17 Cytidylate kinase 0.0015 64-86 / 1-23
PF00265.17 Thymidine kinase 0.0019 62-86 / 2-26
PF13654.5 AAA domain 0.0021 59-86 / 22-49
PF04275.13 Phosphomevalonate kinase 0.0022 66-85 / 1-20
PF03668.14 P-loop ATPase protein family 0.0027 62-83 / 2-23
PF01926.22 50S ribosome-binding GTPase 0.0028 64-84 / 2-22
PF00406.21 Adenylate kinase 0.003 66-86 / 1-21
PF01583.19 Adenylylsulphate kinase 0.0036 62-86 / 3-27
PF02562.15 PhoH-like protein 0.0038 61-83 / 19-41
PF06048.10 Domain of unknown function (DUF927) 0.0038 60-86 / 187-213
PF07475.11 HPr Serine kinase C-terminal domain 0.0042 60-84 / 13-37
PF13207.5 AAA domain 0.0045 67-86 / 1-20
PF01057.16 Parvovirus non-structural protein NS1 0.0047 60-85 / 117-142
PF13245.5 AAA domain 0.0048 61-86 / 11-36
PF13479.5 AAA domain 0.0053 62-83 / 3-24
PF07088.10 GvpD gas vesicle protein 0.0062 59-85 / 8-34
PF13604.5 AAA domain 0.0066 64-81 / 19-36
PF13476.5 AAA domain 0.0069 62-85 / 21-44
PF03796.14 DnaB-like helicase C terminal domain 0.007 61-86 / 19-44
PF07652.13 Flavivirus DEAD domain 0.0075 61-83 / 4-27
PF13481.5 AAA domain 0.0075 61-85 / 28-52
PF00437.19 Type II/IV secretion system protein 0.0082 61-86 / 130-155
PF09439.9 Signal recognition particle receptor beta subunit 0.0087 62-84 / 4-26

Annotations of the NCBI proteins of this PHROG


7:hypothetical protein 4:DnaA-like protein 3:NTP-binding motif containing protein 3:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0000723 telomere maintenance
GO:0003972 RNA ligase (ATP) activity
GO:0004673 protein histidine kinase activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003887 DNA-directed DNA polymerase activity
GO:0004127 cytidylate kinase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0003724 RNA helicase activity
GO:0006139 nucleobase-containing compound metabolic process
GO:0016020 membrane
GO:0051188 cofactor biosynthetic process
GO:0006270 DNA replication initiation
GO:0004140 dephospho-CoA kinase activity
GO:0016887 ATPase activity
GO:0008134 transcription factor binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0043531 ADP binding
GO:0000160 phosphorelay signal transduction system
GO:0009236 cobalamin biosynthetic process
GO:0016740 transferase activity
GO:0006000 fructose metabolic process
GO:0000166 nucleotide binding
GO:0015937 coenzyme A biosynthetic process
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0008026 ATP-dependent helicase activity
GO:0004797 thymidine kinase activity
GO:0005525 GTP binding
GO:0004631 phosphomevalonate kinase activity
GO:0019079 viral genome replication
GO:0004672 protein kinase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0009360 DNA polymerase III complex
GO:0005524 ATP binding
GO:0006281 DNA repair
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0004003 ATP-dependent DNA helicase activity
GO:0006109 regulation of carbohydrate metabolic process
GO:0003723 RNA binding

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