phrog_5534 is made of 23 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
272.7 349 277


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KM411960_p32 AIZ94965.1 ATP-dependent Clp protease ATP-binding subunit ClpX KM411960 Pseudomonas phage phi176 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; Pseudomonas virus Ab09.
MG030347_p59 ATW69942.1 putative ATP-dependent Clp protease MG030347 Proteus phage PM135 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Novosibvirus; Proteus virus PM135.
NC_031062_p31 YP_009286160.1 putative ATP-dependent CLP protease NC_031062 Erwinia phage vB_EamP_Frozen Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Johnsonvirus.
NC_029101_p76 YP_009226172.1 hypothetical protein NC_029101 Pseudomonas phage YH30 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_028885_p54 YP_009206263.1 ATP-dependent Clp protease ATP-binding subunit ClpX NC_028885 Pseudomonas phage DL64 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_031063_p32 YP_009286253.1 ATP dependent protease ATP-binding subunit NC_031063 Pseudomonas phage PEV2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus.
NC_029017_p76 YP_009219025.1 hypothetical protein NC_029017 Pseudomonas phage KPP21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Luzseptimavirus.
NC_019514_p41 YP_007005777.1 gp041 NC_019514 Erwinia phage vB_EamP-S6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
NC_024140_p28 YP_009031805.1 hypothetical protein NC_024140 Pseudomonas phage vB_PaeP_C2-10_Ab09 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus.
NC_027381_p36 YP_009152137.1 hypothetical protein NC_027381 Escherichia phage Pollock Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Ithacavirus.
NC_021772_p39 YP_008239443.1 hypothetical protein NC_021772 Salmonella phage FSL SP-058 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Ithacavirus.
NC_013692_p31 YP_003358428.1 hypothetical protein NC_013692 Pseudomonas phage LIT1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus.
MF490238_p32 ASZ72239.1 hypothetical protein MF490238 Pseudomonas phage vB_PaeP_DEV Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_027388_p36 YP_009152536.1 hypothetical protein NC_027388 Pseudomonas phage YH6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
JX194238_p31 AFO70530.1 hypothetical protein JX194238 Pseudomonas phage PA26 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; Pseudomonas virus PA26.
NC_027345_p32 YP_009148212.1 ATP-dependent Clp protease ATP-binding subunit ClpX NC_027345 Pseudomonas phage Pa2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_013691_p36 YP_003358318.1 hypothetical protein NC_013691 Pseudomonas phage LUZ7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Luzseptimavirus.
KX098390_p31 ANJ65260.1 putative ATP-dependent CLP protease KX098390 Erwinia phage vB_EamP_Rexella Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Johnsonvirus; Erwinia virus Frozen.
MF490236_p32 ASZ72081.1 hypothetical protein MF490236 Pseudomonas phage vB_PaeP_PYO2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_031104_p33 YP_009290567.1 ATP-dependent Clp protease ATP-binding subunit ClpX NC_031104 Pseudomonas phage vB_PaeP_MAG4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
KX171209_p34 ANT44310.1 ATP-dependent Clp protease ATP-binding subunit ClpX KX171209 Pseudomonas phage vB_Pae575P-3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Litunavirus; unclassified Litunavirus.
NC_023579_p32 YP_009007405.1 ATP-dependent CLP protease NC_023579 Erwinia phage Ea9-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Johnsonvirus.
NC_026610_p18 YP_009126575.1 hypothetical protein NC_026610 Vibrio phage VpKK5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4781 28 no annotation unknown function 13 2.55E-54 44.72
phrog_8112 14 no annotation unknown function 13 6.36E-62 52.32
phrog_10440 10 no annotation unknown function 2 1.40E-11 1.98
phrog_6596 18 no annotation unknown function 2 9.53E-11 1.14

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10401 ATPase other 96.4 5.6E-05 26-178 / 202-329
phrog_11143 no annotation unknown function 93.8 0.0067 31-98 / 49-144
phrog_11838 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 97.0 3.4E-06 5-103 / 22-113
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 90.3 0.056 27-49 / 14-36
phrog_1297 ATPase other 95.8 0.00026 28-99 / 26-110
phrog_1366 no annotation unknown function 93.4 0.01 16-126 / 3-142
phrog_14685 no annotation unknown function 91.7 0.031 30-52 / 5-27
phrog_15585 no annotation unknown function 94.9 0.0017 27-152 / 347-468
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 98.4 3.6E-10 28-101 / 39-111
phrog_170 PhoH-like phosphate starvation-inducible other 93.3 0.01 27-48 / 50-71
phrog_1815 guanylate kinase other 95.8 0.00029 30-103 / 5-53
phrog_2071 ATPase other 96.1 0.00013 30-66 / 6-38
phrog_2107 thymidylate kinase other 93.2 0.011 31-52 / 7-28
phrog_21086 no annotation unknown function 93.1 0.012 26-99 / 236-293
phrog_21479 no annotation unknown function 94.5 0.003 31-64 / 30-61
phrog_2376 ATPase other 97.0 4E-06 10-216 / 58-219
phrog_2392 ABC transporter moron, auxiliary metabolic gene and host takeover 93.6 0.0082 23-60 / 363-402
phrog_249 porphyrin biosynthesis moron, auxiliary metabolic gene and host takeover 96.6 2E-05 24-234 / 104-293
phrog_2666 terminase large subunit head and packaging 92.8 0.016 29-49 / 9-29
phrog_29395 no annotation unknown function 96.0 0.00015 27-99 / 137-218
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 94.9 0.0016 29-52 / 40-63
phrog_296 DNA transposition protein integration and excision 96.9 6.3E-06 30-198 / 94-237
phrog_30773 no annotation unknown function 95.5 0.00054 23-126 / 170-271
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 96.6 2E-05 2-166 / 7-176
phrog_35358 DNA primase DNA, RNA and nucleotide metabolism 94.5 0.003 25-49 / 470-494
phrog_3757 no annotation unknown function 97.9 2.3E-08 8-211 / 101-272
phrog_4339 no annotation unknown function 99.8 9.9E-24 90-252 / 315-468
phrog_4412 exonuclease V DNA, RNA and nucleotide metabolism 92.3 0.022 28-249 / 365-594
phrog_4581 terminase small subunit head and packaging 92.8 0.015 27-60 / 121-154
phrog_4871 ATP-dependent protease other 92.3 0.021 30-105 / 204-289
phrog_505 polynucleotide kinase other 91.7 0.031 28-67 / 2-40
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 97.1 2.2E-06 4-100 / 91-186
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 97.4 5.3E-07 22-130 / 33-123
phrog_6891 ATPase other 95.0 0.0015 17-100 / 22-125
phrog_7485 no annotation unknown function 96.9 7.7E-06 28-215 / 228-379
phrog_761 thymidylate kinase other 94.2 0.0046 30-52 / 5-27
phrog_7998 no annotation unknown function 96.9 5.4E-06 25-200 / 36-187
phrog_8638 no annotation unknown function 95.3 0.00092 30-134 / 316-417
phrog_9172 no annotation unknown function 96.8 8.2E-06 22-200 / 92-247

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 3E-09 58-168 / 10-111
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 4.3E-09 94-168 / 32-99
PF00493.22 MCM2/3/5 family 7.9E-09 66-120 / 23-83
PF12775.6 P-loop containing dynein motor region D3 1E-08 69-265 / 12-191
PF00308.17 Bacterial dnaA protein 2E-08 66-118 / 7-57
PF01078.20 Magnesium chelatase, subunit ChlI 3.5E-08 68-119 / 4-47
PF05673.12 Protein of unknown function (DUF815) 3.8E-08 59-118 / 21-78
PF01637.17 ATPase domain predominantly from Archaea 5.9E-08 69-118 / 1-44
PF03215.14 Rad17 cell cycle checkpoint protein 6.1E-08 54-120 / 6-71
PF13173.5 AAA domain 1.7E-07 95-117 / 3-25
PF00158.25 Sigma-54 interaction domain 2E-07 70-119 / 2-47
PF05621.10 Bacterial TniB protein 2.5E-07 67-118 / 14-62
PF13191.5 AAA ATPase domain 2.9E-07 69-118 / 2-48
PF06431.10 Polyomavirus large T antigen C-terminus 4E-07 93-168 / 154-217
PF13177.5 DNA polymerase III, delta subunit 4.1E-07 71-118 / 1-43
PF12780.6 P-loop containing dynein motor region D4 5.8E-07 93-168 / 30-104
PF06068.12 TIP49 C-terminus 6.6E-07 66-119 / 23-75
PF07726.10 ATPase family associated with various cellular activities (AAA) 7.1E-07 96-121 / 1-26
PF10443.8 RNA12 protein 1.3E-06 72-118 / 1-42
PF09820.8 Predicted AAA-ATPase 1.4E-06 66-118 / 14-55
PF14516.5 AAA-like domain 1.8E-06 67-118 / 10-54
PF07693.13 KAP family P-loop domain 4.1E-06 93-118 / 30-55
PF00519.16 Papillomavirus helicase 5.3E-06 93-119 / 261-287
PF07728.13 AAA domain (dynein-related subfamily) 5.9E-06 97-121 / 2-26
PF14532.5 Sigma-54 interaction domain 6.1E-06 94-119 / 21-46
PF05272.10 Virulence-associated protein E 8.2E-06 93-118 / 58-83
PF00004.28 ATPase family associated with various cellular activities (AAA) 9.1E-06 97-168 / 1-73
PF08298.10 PrkA AAA domain 1.1E-05 65-118 / 56-109
PF03969.15 AFG1-like ATPase 1.6E-05 93-119 / 66-92
PF07724.13 AAA domain (Cdc48 subfamily) 2.2E-05 94-118 / 3-27
PF13401.5 AAA domain 2.4E-05 94-118 / 5-29
PF05729.11 NACHT domain 2.8E-05 96-118 / 2-24
PF10923.7 P-loop Domain of unknown function (DUF2791) 3.4E-05 67-118 / 25-73
PF00910.21 RNA helicase 4.3E-05 97-119 / 1-23
PF13654.5 AAA domain 5.1E-05 68-119 / 3-49
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 6.5E-05 97-119 / 1-23
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 6.8E-05 96-118 / 2-24
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 7.1E-05 94-119 / 14-39
PF01695.16 IstB-like ATP binding protein 0.00014 94-118 / 48-72
PF00931.21 NB-ARC domain 0.00016 72-118 / 1-44
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0002 95-120 / 2-27
PF13337.5 Putative ATP-dependent Lon protease 0.00021 93-118 / 205-230
PF00265.17 Thymidine kinase 0.00028 95-118 / 2-25
PF00625.20 Guanylate kinase 0.00028 95-119 / 3-27
PF13521.5 AAA domain 0.00043 97-118 / 2-23
PF06414.11 Zeta toxin 0.00044 93-118 / 13-38
PF01745.15 Isopentenyl transferase 0.00048 95-119 / 2-26
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.0005 93-119 / 27-53
PF13671.5 AAA domain 0.00052 97-119 / 2-24
PF03266.14 NTPase 0.00053 96-118 / 1-23
PF10649.8 Protein of unknown function (DUF2478) 0.00064 97-119 / 1-23
PF13238.5 AAA domain 0.00065 97-119 / 1-23
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00077 94-118 / 4-28
PF13189.5 Cytidylate kinase-like family 0.00079 97-119 / 2-24
PF05127.13 Helicase 0.00098 98-118 / 1-21
PF01591.17 6-phosphofructo-2-kinase 0.0011 94-119 / 9-34
PF04851.14 Type III restriction enzyme, res subunit 0.0011 94-118 / 23-47
PF01712.18 Deoxynucleoside kinase 0.0011 97-119 / 1-23
PF08433.9 Chromatin associated protein KTI12 0.0011 95-119 / 2-26
PF01121.19 Dephospho-CoA kinase 0.0011 96-119 / 2-25
PF08303.10 tRNA ligase kinase domain 0.0014 97-119 / 2-24
PF02224.17 Cytidylate kinase 0.0016 97-121 / 1-25
PF01443.17 Viral (Superfamily 1) RNA helicase 0.002 97-117 / 1-20
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0021 97-119 / 2-24
PF06048.10 Domain of unknown function (DUF927) 0.0024 94-120 / 188-214
PF02223.16 Thymidylate kinase 0.0025 99-119 / 1-21
PF04665.11 Poxvirus A32 protein 0.0026 93-118 / 12-37
PF01926.22 50S ribosome-binding GTPase 0.003 97-117 / 2-22
PF04275.13 Phosphomevalonate kinase 0.0035 99-118 / 1-20
PF00406.21 Adenylate kinase 0.0036 99-119 / 1-21
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.0041 95-118 / 2-25
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0044 93-118 / 23-48
PF03668.14 P-loop ATPase protein family 0.005 95-116 / 2-23
PF07475.11 HPr Serine kinase C-terminal domain 0.0053 94-117 / 14-37
PF13207.5 AAA domain 0.0055 100-119 / 1-20
PF05970.13 PIF1-like helicase 0.0057 94-118 / 22-46
PF01583.19 Adenylylsulphate kinase 0.0059 95-118 / 3-26
PF02562.15 PhoH-like protein 0.0064 94-116 / 19-41
PF01057.16 Parvovirus non-structural protein NS1 0.0075 94-119 / 118-143
PF06309.10 Torsin 0.0075 68-119 / 25-77
PF13245.5 AAA domain 0.0077 94-118 / 11-35
PF13479.5 AAA domain 0.0081 95-116 / 3-24
PF00437.19 Type II/IV secretion system protein 0.0083 94-119 / 130-155
PF05707.11 Zonular occludens toxin (Zot) 0.0083 96-114 / 2-20
PF09439.9 Signal recognition particle receptor beta subunit 0.0086 95-117 / 4-26

Annotations of the NCBI proteins of this PHROG


10:hypothetical protein 5:ATP-dependent Clp protease ATP-binding subunit ClpX 3:ATP-dependent CLP protease 3:protein of an unannotated phage 1:ATP dependent protease ATP-binding subunit 1:ATP-dependent Clp protease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03544 clpX, CLPX : ATP-dependent Clp protease ATP-binding subunit ClpX ko04112 Cell cycle - Caulobacter 98 15
K13525 VCP, CDC48 : transitional endoplasmic reticulum ATPase ko04141 Protein processing in endoplasmic reticulum
ko05134 Legionellosis
56 2
K13338 PEX1 : peroxin-1 ko04146 Peroxisome 53 4
K12196 VPS4 : vacuolar protein-sorting-associated protein 4 ko04144 Endocytosis 52 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004672 protein kinase activity
GO:0000155 phosphorelay sensor kinase activity
GO:0009058 biosynthetic process
GO:0019079 viral genome replication
GO:0004797 thymidine kinase activity
GO:0005525 GTP binding
GO:0004631 phosphomevalonate kinase activity
GO:0003723 RNA binding
GO:0008152 metabolic process
GO:0016301 kinase activity
GO:0006281 DNA repair
GO:0006109 regulation of carbohydrate metabolic process
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0004127 cytidylate kinase activity
GO:0016787 hydrolase activity
GO:0009378 four-way junction helicase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003873 6-phosphofructo-2-kinase activity
GO:0006695 cholesterol biosynthetic process
GO:0004161 dimethylallyltranstransferase activity
GO:0004673 protein histidine kinase activity
GO:0000723 telomere maintenance
GO:0003972 RNA ligase (ATP) activity
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0015937 coenzyme A biosynthetic process
GO:0016740 transferase activity
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0006270 DNA replication initiation
GO:0004140 dephospho-CoA kinase activity
GO:0016887 ATPase activity
GO:0009236 cobalamin biosynthetic process
GO:0043531 ADP binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0008134 transcription factor binding
GO:0006139 nucleobase-containing compound metabolic process
GO:0003724 RNA helicase activity
GO:0016020 membrane
GO:0051188 cofactor biosynthetic process

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