phrog_5536 is made of 23 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
172.26 200 172


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p166286 no NCBI prot ID no annotation VI_04146 Actinobacteria_gi_550255506 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Rhodococcus phage REQ3.
NC_016654_p34 YP_005087226.1 hypothetical protein NC_016654 Rhodococcus phage REQ3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p367979 no NCBI prot ID no annotation VI_04085 Actinobacteria_gi_288922827 Viruses.
p289445 no NCBI prot ID no annotation VI_00055 Actinobacteria_gi_484040487 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY676784_p52 ARB11474.1 helix-turn-helix DNA binding domain protein KY676784 Streptomyces phage ToastyFinz Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Raleighvirus; unclassified Raleighvirus.
NC_018848_p55 YP_006906997.1 hypothetical protein NC_018848 Streptomyces phage SV1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; unclassified Picardvirus.
KY092481_p54 APD18634.1 helix-turn-helix DNA binding domain protein KY092481 Streptomyces phage PapayaSalad Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; Streptomyces virus PapayaSalad.
KY092483_p54 APD18746.1 helix-turn-helix DNA binding domain protein KY092483 Streptomyces phage Bioscum Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; unclassified Austintatiousvirus.
p328060 no NCBI prot ID no annotation VI_00052 Actinobacteria_gi_484035204 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p226965 no NCBI prot ID no annotation VI_00061 Actinobacteria_gi_482937413 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p284844 no NCBI prot ID no annotation VI_00050 Actinobacteria_gi_484033837 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p389663 no NCBI prot ID no annotation VI_00053 Actinobacteria_gi_484036214 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KY092479_p55 APD18531.1 helix-turn-helix DNA binding domain protein KY092479 Streptomyces phage Ididsumtinwong Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; Streptomyces virus Ididsumtinwong.
KY092480_p56 APD18585.1 helix-turn-helix DNA binding domain protein KY092480 Streptomyces phage Picard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; Streptomyces virus Picard.
p211940 no NCBI prot ID no annotation VI_00049 Actinobacteria_gi_484032675_42320_77942 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY092482_p56 APD18697.1 helix-turn-helix DNA binding domain protein KY092482 Streptomyces phage Mojorita Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; unclassified Picardvirus.
KY092484_p53 APD18801.1 helix-turn-helix DNA binding domain protein KY092484 Streptomyces phage Raleigh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Raleighvirus; Streptomyces virus Raleigh.
p261643 no NCBI prot ID no annotation VI_00040 Actinobacteria_gi_483969925 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p34977 no NCBI prot ID no annotation VI_04131 Actinobacteria_gi_484014952 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p339990 no NCBI prot ID no annotation VI_04086 Actinobacteria_gi_317512503 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p230324 no NCBI prot ID no annotation VI_04092 Actinobacteria_gi_440701504_0_33798 Viruses.
p323414 no NCBI prot ID no annotation VI_04101 Actinobacteria_gi_484867420 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; unclassified Picardvirus; Streptomyces phage SV1.
p17961 no NCBI prot ID no annotation VI_00036 Actinobacteria_gi_482936492 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2 5795 terminase large subunit head and packaging 15 5.54E-26 16.38
phrog_16946 5 no annotation unknown function 5 0 1000
phrog_12816 8 no annotation unknown function 5 7.39E-26 16.25
phrog_14428 7 no annotation unknown function 4 1.61E-21 11.92
phrog_28863 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1033 ParB-like partition protein DNA, RNA and nucleotide metabolism 91.7 0.03 3-42 / 122-162
phrog_11138 no annotation unknown function 92.1 0.024 5-41 / 91-127
phrog_11420 DNA binding protein DNA, RNA and nucleotide metabolism 90.4 0.056 2-45 / 6-49
phrog_1157 transposase integration and excision 95.5 0.00058 6-44 / 2-40
phrog_1206 terminase small subunit head and packaging 90.2 0.059 8-92 / 3-116
phrog_1373 transcriptional regulator transcription regulation 94.5 0.0029 16-50 / 39-74
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 92.6 0.018 19-43 / 21-45
phrog_151 transposase integration and excision 94.7 0.0024 2-43 / 3-45
phrog_1529 no annotation unknown function 92.5 0.019 9-43 / 3-37
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 8.6E-06 5-46 / 54-95
phrog_2104 no annotation unknown function 91.5 0.033 5-43 / 44-80
phrog_2308 no annotation unknown function 91.2 0.039 6-48 / 1-43
phrog_26674 no annotation unknown function 90.6 0.051 9-42 / 129-162
phrog_27475 no annotation unknown function 90.0 0.065 6-54 / 2-52
phrog_323 transcriptional regulator, D5-like transcription regulation 90.4 0.054 3-49 / 2-43
phrog_3282 sigma factor transcription regulation 92.1 0.024 17-43 / 28-54
phrog_3512 sigma factor transcription regulation 93.3 0.011 3-43 / 64-104
phrog_351 RNA polymerase sigma factor transcription regulation 92.8 0.015 5-43 / 175-216
phrog_35602 no annotation unknown function 92.3 0.021 9-48 / 33-72
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.6 2E-05 7-50 / 65-111
phrog_3 transcriptional repressor transcription regulation 91.8 0.028 19-43 / 14-38
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.028 10-46 / 9-45
phrog_4646 transposase integration and excision 95.1 0.0013 4-48 / 5-49
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.9 0.00025 5-43 / 63-101
phrog_609 RIIB lysis inhibitor lysis 90.0 0.064 7-54 / 8-56
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 96.3 7.6E-05 3-48 / 16-61
phrog_6223 transcriptional repressor transcription regulation 95.1 0.0013 18-43 / 14-39
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 91.9 0.028 5-47 / 3-45
phrog_6831 transcriptional regulator transcription regulation 95.9 0.00022 12-53 / 6-50
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.2 0.059 12-43 / 35-66
phrog_7676 no annotation unknown function 95.6 0.00047 18-44 / 13-39
phrog_769 transcriptional repressor transcription regulation 90.4 0.056 13-43 / 17-47
phrog_836 late transcriptional activator transcription regulation 92.2 0.023 12-46 / 93-134
phrog_8 transcriptional regulator transcription regulation 92.0 0.025 13-44 / 5-36
phrog_9129 no annotation unknown function 95.8 0.00026 8-79 / 73-143
phrog_9366 transposase integration and excision 91.7 0.03 13-44 / 73-104

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00292.17 'Paired box' domain 5.6E-08 6-55 / 12-61
PF08822.10 Protein of unknown function (DUF1804) 1.1E-07 11-56 / 2-48
PF01710.15 Transposase 6.6E-07 11-53 / 2-44
PF13011.5 leucine-zipper of insertion element IS481 1.5E-06 8-56 / 4-53
PF04936.11 Protein of unknown function (DUF658) 4.2E-06 27-120 / 14-114
PF09607.9 Brinker DNA-binding domain 6.2E-06 9-53 / 3-51
PF07141.10 Putative bacteriophage terminase small subunit 7.3E-06 6-53 / 6-57
PF12759.6 InsA C-terminal domain 1.4E-05 10-51 / 4-45
PF07750.10 GcrA cell cycle regulator 2.1E-05 11-54 / 2-46
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 3.6E-05 17-56 / 3-42
PF13542.5 Helix-turn-helix domain of transposase family ISL3 4.5E-05 6-51 / 6-50
PF10668.8 Phage terminase small subunit 5.5E-05 10-56 / 3-51
PF06627.10 Protein of unknown function (DUF1153) 5.8E-05 7-57 / 25-76
PF16087.4 Domain of unknown function (DUF4817) 0.0001 14-55 / 2-52
PF02796.14 Helix-turn-helix domain of resolvase 0.00011 12-50 / 6-44
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00012 9-52 / 4-48
PF11427.7 Tc3 transposase 0.00016 11-53 / 4-46
PF13936.5 Helix-turn-helix domain 0.00016 11-50 / 4-43
PF01527.19 Transposase 0.00017 10-55 / 3-48
PF05344.10 Domain of Unknown Function (DUF746) 0.00023 25-55 / 10-40
PF16677.4 DNA-packaging protein gp3 0.00025 10-51 / 4-53
PF04552.12 Sigma-54, DNA binding domain 0.0003 9-53 / 28-74
PF13309.5 HTH domain 0.0003 9-49 / 17-63
PF13518.5 Helix-turn-helix domain 0.00036 18-56 / 3-40
PF14493.5 Helix-turn-helix domain 0.0004 19-55 / 4-40
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.00043 12-53 / 3-45
PF10654.8 Protein of unknown function (DUF2481) 0.00046 11-51 / 64-104
PF06322.10 Phage NinH protein 0.00047 17-54 / 5-43
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00066 12-52 / 40-80
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.00077 8-51 / 85-131
PF13411.5 MerR HTH family regulatory protein 0.00078 29-52 / 2-25
PF13384.5 Homeodomain-like domain 0.00082 15-51 / 5-41
PF05225.15 helix-turn-helix, Psq domain 0.0012 17-52 / 5-42
PF13551.5 Winged helix-turn helix 0.0012 20-56 / 4-40
PF13412.5 Winged helix-turn-helix DNA-binding 0.0012 26-54 / 16-44
PF05331.10 Protein of unknown function (DUF742) 0.0015 10-55 / 37-81
PF02954.18 Bacterial regulatory protein, Fis family 0.0014 26-50 / 15-39
PF08765.10 Mor transcription activator family 0.0015 19-52 / 65-97
PF13022.5 Helix-turn-helix of insertion element transposase 0.0015 10-49 / 5-47
PF07638.10 ECF sigma factor 0.0019 12-52 / 134-174
PF01371.18 Trp repressor protein 0.002 17-53 / 38-74
PF15978.4 Tn7-like transposition protein D 0.0025 11-55 / 186-231
PF13404.5 AsnC-type helix-turn-helix domain 0.0033 26-51 / 16-41
PF08281.11 Sigma-70, region 4 0.0034 12-52 / 11-51
PF16509.4 TrfB plasmid transcriptional repressor 0.0036 11-53 / 15-57
PF17443.1 Uncharacterized protein pXO2-72 0.0046 26-51 / 7-32
PF04545.15 Sigma-70, region 4 0.0051 12-51 / 5-48
PF08535.9 KorB domain 0.0053 26-54 / 2-30
PF06413.10 Neugrin 0.0056 7-50 / 6-52
PF11242.7 Protein of unknown function (DUF2774) 0.0055 19-54 / 6-41
PF01381.21 Helix-turn-helix 0.0058 26-50 / 8-32
PF02042.14 RWP-RK domain 0.0062 26-53 / 11-38
PF00356.20 Bacterial regulatory proteins, lacI family 0.0065 29-50 / 1-22
PF00376.22 MerR family regulatory protein 0.0069 30-51 / 2-23
PF13556.5 PucR C-terminal helix-turn-helix domain 0.007 26-54 / 11-39
PF07453.12 NUMOD1 domain 0.0076 28-48 / 20-40

Annotations of the NCBI proteins of this PHROG


7:helix-turn-helix DNA binding domain protein 2:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0005524 ATP binding
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0003700 DNA binding transcription factor activity
GO:0019069 viral capsid assembly
GO:0016987 sigma factor activity
GO:0006355 regulation of transcription, DNA-templated
GO:0006352 DNA-templated transcription, initiation
GO:0005622 intracellular

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