phrog_5823 is made of 22 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
401.27 457 407


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028952_p26 YP_009213153.1 hypothetical protein NC_028952 Streptomyces phage SF3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_028807_p46 YP_009199294.1 hypothetical protein NC_028807 Streptomyces phage SF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p241802 no NCBI prot ID no annotation VI_04140 Actinobacteria_gi_441157011 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KU958700_p24 AMS01583.1 DNA-binding protein KU958700 Streptomyces phage Chymera Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p26681 no NCBI prot ID no annotation VI_04091 Actinobacteria_gi_440697762 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MH001460_p53 AVO22536.1 helix-turn-helix DNA binding domain protein MH001460 Streptomyces phage Paedore Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
KT021004_p44 ALA06417.1 transcriptional regulator KT021004 Thermobifida phage P1312 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p292417 no NCBI prot ID no annotation VI_00051 Actinobacteria_gi_484033862 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF766046_p50 ATI18834.1 helix-turn-helix DNA binding domain protein MF766046 Streptomyces phage Diane Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
JX262376_p51 AFO10917.1 putative DNA-binding protein JX262376 Streptomyces phage phiELB20 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; Streptomyces virus ELB20.
NC_019414_p51 YP_006990166.1 putative DNA binding protein, XRE family NC_019414 Streptomyces phage R4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus.
p148141 no NCBI prot ID no annotation VI_04137 Actinobacteria_gi_484024199 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p211968 no NCBI prot ID no annotation VI_00049 Actinobacteria_gi_484032675_42320_77942 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF766048_p52 ATI18992.1 helix-turn-helix DNA binding domain protein MF766048 Streptomyces phage Tefunt Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
p370853 no NCBI prot ID no annotation VI_04087 Actinobacteria_gi_317512533 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_018836_p47 YP_006906227.1 putative XRE regulator NC_018836 Streptomyces phage phiHau3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae.
MF766044_p50 ATI18672.1 helix-turn-helix DNA binding domain protein MF766044 Streptomyces phage Amethyst Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
MF766045_p51 ATI18752.1 helix-turn-helix DNA binding domain protein MF766045 Streptomyces phage Daudau Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
MG593801_p44 AUG87176.1 helix-turn-helix DNA binding domain protein MG593801 Streptomyces phage Attoomi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Attoomivirus; Streptomyces virus Attoomi.
MF766047_p50 ATI18913.1 helix-turn-helix DNA binding domain protein MF766047 Streptomyces phage SqueakyClean Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
NC_005345_p57 NP_958298.1 hypothetical protein NC_005345 Streptomyces phage VWB Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY092481_p28 APD18612.1 transcriptional regulator KY092481 Streptomyces phage PapayaSalad Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; Streptomyces virus PapayaSalad.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_15135 6 no annotation unknown function 6 0 1000
phrog_25407 3 no annotation unknown function 2 3.70E-14 4.55
phrog_28759 2 no annotation unknown function 2 0 1000
phrog_38395 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10886 transcriptional regulator transcription regulation 96.6 2.6E-05 4-359 / 3-403
phrog_1124 transcriptional regulator transcription regulation 91.0 0.042 2-61 / 4-64
phrog_13326 no annotation unknown function 92.1 0.025 18-94 / 18-97
phrog_1373 transcriptional regulator transcription regulation 98.1 3.9E-09 5-65 / 32-91
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 95.2 0.0011 2-64 / 7-69
phrog_14076 transcriptional regulator transcription regulation 94.3 0.0038 6-43 / 3-43
phrog_14639 cro-like repressor transcription regulation 94.7 0.0022 6-76 / 8-80
phrog_1468 transcriptional repressor transcription regulation 90.0 0.064 3-60 / 6-61
phrog_147 transcriptional regulator transcription regulation 96.8 1.2E-05 3-58 / 1-57
phrog_1994 DNA binding protein DNA, RNA and nucleotide metabolism 92.3 0.021 7-69 / 2-63
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 90.5 0.054 3-38 / 54-91
phrog_2104 no annotation unknown function 97.0 4.7E-06 7-45 / 48-86
phrog_2328 transcriptional repressor transcription regulation 97.8 2.8E-08 3-70 / 14-80
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.9 0.0002 5-62 / 25-82
phrog_24325 transcriptional regulator transcription regulation 91.4 0.036 6-72 / 54-120
phrog_2439 transcriptional regulator transcription regulation 97.6 1.1E-07 3-123 / 5-146
phrog_2967 transcriptional regulator transcription regulation 97.8 5E-08 2-72 / 6-76
phrog_32768 no annotation unknown function 96.2 9.8E-05 3-68 / 8-73
phrog_34939 no annotation unknown function 94.7 0.0023 3-72 / 8-77
phrog_36081 no annotation unknown function 91.1 0.041 3-97 / 1-89
phrog_37057 transcriptional regulator transcription regulation 93.9 0.0059 16-62 / 9-53
phrog_38027 transcriptional repressor transcription regulation 95.7 0.00033 7-66 / 60-118
phrog_3949 transcriptional repressor transcription regulation 91.2 0.039 19-66 / 30-75
phrog_3 transcriptional repressor transcription regulation 97.7 9.5E-08 4-67 / 3-65
phrog_4031 no annotation unknown function 95.1 0.0012 5-59 / 516-570
phrog_4268 transcriptional repressor transcription regulation 92.6 0.018 4-62 / 35-90
phrog_4583 transcriptional repressor transcription regulation 95.3 0.00081 4-70 / 10-75
phrog_4779 transcriptional regulator transcription regulation 92.2 0.023 6-43 / 3-40
phrog_4836 CII-like regulator transcription regulation 96.3 7.7E-05 2-72 / 80-149
phrog_4 transcriptional repressor transcription regulation 96.9 6.4E-06 3-73 / 2-67
phrog_5119 no annotation unknown function 94.2 0.0044 5-46 / 54-95
phrog_6223 transcriptional repressor transcription regulation 95.2 0.001 5-53 / 7-53
phrog_6288 no annotation unknown function 95.8 0.0003 4-58 / 11-66
phrog_6463 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.0 0.00016 9-70 / 25-93
phrog_6499 transcriptional regulator transcription regulation 94.6 0.0025 10-60 / 12-67
phrog_6831 transcriptional regulator transcription regulation 96.8 1.2E-05 9-57 / 8-56
phrog_6962 no annotation unknown function 95.1 0.0013 5-53 / 2-49
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.3 6E-05 16-73 / 28-89
phrog_7241 transcriptional regulator transcription regulation 98.2 1.5E-09 10-65 / 67-121
phrog_7396 no annotation unknown function 90.2 0.06 4-74 / 12-83
phrog_7950 transcriptional repressor transcription regulation 94.9 0.0016 6-43 / 11-48
phrog_8 transcriptional regulator transcription regulation 98.1 3.4E-09 4-70 / 1-64
phrog_9103 transcriptional repressor transcription regulation 94.4 0.0036 9-69 / 11-71
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.5 0.0086 4-67 / 36-101
phrog_9908 DNA binding protein DNA, RNA and nucleotide metabolism 90.7 0.048 5-60 / 15-69

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF14938.5 Soluble NSF attachment protein, SNAP 0.00011 94-206 / 161-266
PF13429.5 Tetratricopeptide repeat 1.3E-06 177-379 / 13-187
PF08631.9 Meiosis protein SPO22/ZIP4 like 6E-05 271-378 / 2-115
PF16918.4 Protein kinase G tetratricopeptide repeat 0.00026 231-377 / 37-158
PF04733.13 Coatomer epsilon subunit 2.9E-06 94-248 / 138-266
PF12569.7 NMDA receptor-regulated protein 1 5.6E-07 126-287 / 304-507
PF04184.11 ST7 protein 0.00033 95-229 / 304-431
PF07079.10 Protein of unknown function (DUF1347) 1.3E-09 178-376 / 8-199
PF17139.3 Domain of unknown function (DUF5112) 2.8E-07 218-376 / 4-157
PF10345.8 Cohesin loading factor 1.1E-10 95-285 / 188-425
PF13281.5 Domain of unknown function (DUF4071) 0.00013 97-238 / 245-364
PF10300.8 Protein of unknown function (DUF3808) 7.2E-06 182-247 / 3-66
PF02259.22 FAT domain 0.00068 222-376 / 5-137
PF04348.12 LppC putative lipoprotein 1.8E-05 217-247 / 165-196
PF13525.5 Outer membrane lipoprotein 9E-07 96-238 / 53-207
PF10602.8 26S proteasome subunit RPN7 2.6E-06 96-207 / 48-145
PF10037.8 Mitochondrial 28S ribosomal protein S27 0.00031 99-244 / 197-362
PF16811.4 TRAP transporter T-component 2E-05 98-206 / 125-219
PF09477.9 Bacterial type II secretion system chaperone protein (type_III_yscG) 1.3E-07 261-377 / 6-98
PF17177.3 Pentacotripeptide-repeat region of PRORP 1E-05 215-376 / 11-155
PF04910.13 Transcriptional repressor TCF25 0.00086 95-207 / 108-206
PF09976.8 Tetratricopeptide repeat-like domain 1.8E-07 96-248 / 51-179
PF09613.9 Bacterial type III secretion protein (HrpB1_HrpK) 0.0039 95-155 / 62-114
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.5E-08 16-81 / 7-77
PF05843.13 Suppressor of forked protein (Suf) 0.00015 98-205 / 50-136
PF13744.5 Helix-turn-helix domain 1.7E-07 15-80 / 14-79
PF12968.6 Domain of Unknown Function (DUF3856) 2.7E-05 96-208 / 21-133
PF13512.5 Tetratricopeptide repeat 2.1E-06 214-379 / 9-134
PF09295.9 ChAPs (Chs5p-Arf1p-binding proteins) 0.00016 96-205 / 235-331
PF06552.11 Plant specific mitochondrial import receptor subunit TOM20 0.0015 272-379 / 2-112
PF08424.9 NRDE-2, necessary for RNA interference 0.0025 97-206 / 80-188
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 5.4E-07 24-84 / 3-62
PF14590.5 Domain of unknown function (DUF4447) 7.7E-07 18-84 / 6-74
PF13443.5 Cro/C1-type HTH DNA-binding domain 9.4E-07 24-83 / 2-63
PF01381.21 Helix-turn-helix 1.1E-06 25-79 / 2-55
PF12688.6 Tetratrico peptide repeat 3.5E-05 263-375 / 3-102
PF05339.10 Protein of unknown function (DUF739) 1.5E-06 21-81 / 5-64
PF13413.5 Helix-turn-helix domain 1.8E-06 25-77 / 2-59
PF04645.11 Protein of unknown function, DUF603 1.8E-06 16-86 / 4-73
PF12844.6 Helix-turn-helix domain 2.5E-06 24-83 / 4-62
PF04781.11 Protein of unknown function (DUF627) 4.7E-05 268-376 / 2-106
PF14561.5 Tetratricopeptide repeat 0.00034 275-376 / 2-87
PF05269.10 Bacteriophage CII protein 6.5E-06 19-87 / 8-75
PF13560.5 Helix-turn-helix domain 9E-06 20-79 / 2-63
PF08667.9 BetR domain 1.5E-05 18-86 / 4-75
PF12862.6 Anaphase-promoting complex subunit 5 0.0034 96-157 / 10-76
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.6E-05 20-81 / 70-129
PF06239.10 Evolutionarily conserved signalling intermediate in Toll pathway 0.0004 184-374 / 14-191
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 2.1E-05 27-84 / 4-59
PF10858.7 Protein of unknown function (DUF2659) 5.3E-05 261-379 / 92-207
PF10952.7 Protein of unknown function (DUF2753) 0.0018 311-379 / 4-82
PF08965.9 Domain of unknown function (DUF1870) 3.5E-05 21-83 / 3-69
PF09986.8 Uncharacterized protein conserved in bacteria (DUF2225) 0.00077 95-205 / 87-191
PF04053.13 Coatomer WD associated region 0.0018 269-374 / 325-415
PF12895.6 Anaphase-promoting complex, cyclosome, subunit 3 0.0016 274-372 / 2-93
PF14549.5 DNA-binding transcriptional regulator Cro 5.9E-05 24-80 / 2-53
PF13693.5 Winged helix-turn-helix DNA-binding 7.8E-05 23-84 / 6-63
PF15015.5 Spermatogenesis-associated, N-terminal 0.0015 266-374 / 177-285
PF17004.4 Putative TPR-like repeat 0.0011 267-370 / 20-90
PF13424.5 Tetratricopeptide repeat 0.0024 310-377 / 5-73
PF02376.14 CUT domain 0.00031 18-86 / 6-72
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00034 18-73 / 6-64
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00035 21-73 / 115-166
PF08579.10 Mitochondrial ribonuclease P subunit (RPM2) 0.002 189-289 / 2-96
PF11349.7 Protein of unknown function (DUF3151) 0.0081 213-293 / 33-123
PF10579.8 Rapsyn N-terminal myristoylation and linker region 0.0066 309-379 / 7-75
PF12116.7 Stage III sporulation protein D 0.00059 30-75 / 17-62
PF10654.8 Protein of unknown function (DUF2481) 0.0011 28-57 / 76-105
PF13371.5 Tetratricopeptide repeat 0.0017 222-292 / 2-60
PF16266.4 Domain of unknown function (DUF4919) 0.0018 225-294 / 60-117
PF00356.20 Bacterial regulatory proteins, lacI family 0.0016 34-70 / 1-36
PF14559.5 Tetratricopeptide repeat 0.0019 97-157 / 4-58
PF10373.8 Est1 DNA/RNA binding domain 0.0072 195-277 / 2-66
PF13432.5 Tetratricopeptide repeat 0.0052 221-291 / 3-62
PF03704.16 Bacterial transcriptional activator domain 0.0051 123-206 / 59-126

Annotations of the NCBI proteins of this PHROG


7:helix-turn-helix DNA binding domain protein 2:transcriptional regulator 2:protein of an unannotated phage 2:DNA-binding protein 1:hypothetical protein 1:DNA binding protein, XRE family 1:XRE regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0033130 acetylcholine receptor binding
GO:0005634 nucleus
GO:0009405 pathogenesis
GO:0005794 Golgi apparatus
GO:0043565 sequence-specific DNA binding
GO:0007283 spermatogenesis
GO:0006355 regulation of transcription, DNA-templated
GO:0007064 mitotic sister chromatid cohesion
GO:0051321 meiotic cell cycle
GO:0016192 vesicle-mediated transport
GO:0003700 DNA binding transcription factor activity
GO:0007268 chemical synaptic transmission
GO:0005515 protein binding
GO:0030117 membrane coat
GO:0003677 DNA binding
GO:0005198 structural molecule activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0043495 protein membrane anchor
GO:0006397 mRNA processing
GO:0006886 intracellular protein transport
GO:0045892 negative regulation of transcription, DNA-templated

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