PHROGS

Average length of proteins	Number of columns in the MSA	Number of conserved columns in the MSA
232.23	317	239

List of all proteins of this PHROG

PHROG prot ID	NCBI prot ID	NCBI prot annotation	Virus ID (click to view)	Virus name	Virus taxonomy
JF957059_p128	AEJ92184.1	bifunctional DNA primase/polymerase	JF957059	Mycobacterium virus Optimus	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF937101_p140	AEK09520.1	primase/polymerase	JF937101	Mycobacterium virus Littlee	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_022066_p129	YP_008410287.1	DNA polymerase/DNA primase	NC_022066	Mycobacterium phage Redno2	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_028953_p137	YP_009213354.1	DNA primase/polymerase	NC_028953	Mycobacterium phage MiaZeal	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_023738_p121	YP_009018132.1	gp121	NC_023738	Mycobacterium phage Thibault	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF133445_p130	ASD53523.1	DNA primase/polymerase	MF133445	Mycobacterium phage Lucky2013	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_026590_p93	YP_009124836.1	polymerase primase	NC_026590	Mycobacterium phage Gaia	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gaiavirus.
MF919534_p135	ATS92976.1	DNA primase/polymerase	MF919534	Mycobacterium phage Superphikiman	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF072690_p134	ASD50854.1	DNA primase/polymerase	MF072690	Mycobacterium phage Porcelain	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919512_p134	ATN89847.1	DNA primase/polymerase	MF919512	Mycobacterium phage Klein	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_028876_p137	YP_009205267.1	DNA primase/polymerase	NC_028876	Mycobacterium phage Ariel	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
JF937090_p137	AEK08193.1	DNA primase	JF937090	Mycobacterium virus Baka	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF668284_p134	ASZ74210.1	DNA primase/polymerase	MF668284	Mycobacterium phage Squint	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_004688_p144	NP_818445.1	gp145	NC_004688	Mycobacterium virus Omega	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF919504_p137	ATN88944.1	DNA primase/polymerase	MF919504	Mycobacterium phage DmpstrDiver	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_022067_p136	YP_008410525.1	DNA polymerase/primase	NC_022067	Mycobacterium phage Wanda	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_023690_p133	YP_009012032.1	gp133	NC_023690	Mycobacterium virus Courthouse	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_023744_p77	YP_009018765.1	gp77	NC_023744	Mycobacterium phage DS6A	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p40310	no NCBI prot ID	no annotation	VI_04151	Actinobacteria_gi_484231591	Viruses.
NC_026584_p136	YP_009124089.1	DNA primase/polymerase	NC_026584	Mycobacterium phage Minerva	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
p17998	no NCBI prot ID	no annotation	VI_00036	Actinobacteria_gi_482936492	Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p241807	no NCBI prot ID	no annotation	VI_04140	Actinobacteria_gi_441157011	Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG	#Prot	Annotation	Category	#Neighbors	Probability	Score
phrog_6706	18	no annotation	unknown function	18	0	1000
phrog_5254	25	no annotation	unknown function	14	2.05E-60	50.81
phrog_826	174	HNH endonuclease	DNA, RNA and nucleotide metabolism	4	2.16E-13	3.79

PHROGs similar to this PHROG

PHROG	Annotation	Category	Probability	Evalue	posQ/posS
phrog_10729	DNA polymerase/primase	DNA, RNA and nucleotide metabolism	97.7	9.3E-08	68-229 / 16-163
phrog_1156	DNA primase	DNA, RNA and nucleotide metabolism	99.4	2.7E-17	65-231 / 5-158
phrog_19930	DNA polymerase/primase	DNA, RNA and nucleotide metabolism	96.0	0.00019	68-228 / 10-187
phrog_3022	DNA primase	DNA, RNA and nucleotide metabolism	97.2	1.1E-06	70-219 / 4-152
phrog_5177	DNA polymerase/primase	DNA, RNA and nucleotide metabolism	99.5	1.6E-18	53-227 / 7-170
phrog_695	DNA polymerase/primase	DNA, RNA and nucleotide metabolism	99.7	6.3E-21	68-234 / 5-154
phrog_906	DNA polymerase/primase	DNA, RNA and nucleotide metabolism	99.2	7.3E-15	69-229 / 22-238

PFAMs similar to this PHROG

ID	Definition	Evalue	posQ/posS
PF09250.10	Bifunctional DNA primase/polymerase, N-terminal	2.8E-17	128-241 / 46-161

Annotations of the NCBI proteins of this PHROG

9:DNA primase/polymerase 2:DNA polymerase/DNA primase 2:DNA primase 2:hypothetical protein 1:primase/polymerase 1:bifunctional DNA primase/polymerase 1:polymerase primase 1:DNA polymerase/primase

KEGG orthologous groups similar to this PHROG

ID	Name : Definition	Pathways	BestScore	#Hits
no KEGG group similar to this PHROG

GO terms in Uniprot proteins similar to this PHROG

ID	Definition
no GO term

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>JF957059_p128
MLAFSRCEECQTGMRVL--YVGQQ-------THPGCKKTEEERKL---------------
---------------QEFVEAVQRGDEKAADKLEAAINKPKP-A-KLGPSALWYAK-SGW
PVFPLAVGDKLPAIPSAHPKGDPLRGVCKG-ECGKLGHGLYDATTDPKQIKAWW-----S
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GISGYVCAPPSRVN--GRQYTWIIKPSPEILK
GAS--------------
>JF937101_p140
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>NC_022066_p129
MLAFSRCEECQTGMRVL--YVGQQ-------THPGCKKTEEERKL---------------
---------------QEFVEAVQRGDEKAADKLEAAINKPKP-A-KLGPSALWYAK-SGW
PVFPLAVGDKLPAIPSAHPKGDPLRGVCKG-ECGKLGHGLYDATTDPKQIKAWW-----S
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GISGYVCAPPSRVN--GRQYTWIIKPSPEILK
GAS--------------
>NC_028953_p137
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>NC_023738_p121
MLAFSRCEECQTGMRVL--YVGQQ-------THPGCKKTEEERKL---------------
---------------QEFVEAVQRGDEKAADKLEAAINKPKP-A-KLGPSALWYAK-SGW
PVFPLAVGDKLPAIPSAHPKGDPLRGVCKG-ECGKLGHGLYDATTDPKQIKAWW-----S
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GISGYVCAPPSRVN--GRQYTWIIKPSPEILK
GAS--------------
>MF133445_p130
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>NC_026590_p93
MRQFSTCATCGDILQVT--WVGQL-------THPTCKQTDEEVKL---------------
---------------RAFVDAAQRGDDKAADKLASELNESAP-AVSLGSAALWYAS-VGW
KVFPCAVGGKLPAIPSAHRKGDPLEGRCQG-ECGQLGHGLYDATSDPNLIKQWW-----S
T-RDYNIGIRTGL--TFDVIDQDGPVGVKTLAMWSDEGSLPDVHGKVSTTREDGGMHLYI
LPTGAGNKARMDKHENPPGGIDYR----GQGGYVLAPPSIVD--GKRYTWMSKPSPEIMG
RAHAQAS----------
>MF919534_p135
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWTIKPSPEILR
KTK--------------
>MF072690_p134
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>MF919512_p134
MLTYSQCRSCNEILQVT--WVGQE-------THPSCPQTEEELKL---------------
---------------RAFVDAIQRGDESAADKLEAEINKPKP-A-KLGPSALWYAKKAGW
AVFPLVPGEKRPATR----------------------NGFKDATRDGAQIRRWW-----T
ENPNYNIGLPTGKTAGFDVVDVDGPQGVQSLAELGE-GVLPPVHGKVETP---RGFHLYV
LGTADGNRAGV------RPGIDYR----SEGGFVVAVPSIVN--GKRYSWVVRPSPEIMR
A----------------
>NC_028876_p137
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>JF937090_p137
-------------MRVL--YVGQQ-------THPGCKKTEEERKL---------------
---------------QEFVEAVQRGDEKAADKLEAAINKPKP-A-KLGPSALWYAK-SGW
PVFPLAVGDKLPAIPSAHPKGDPLRGVCKG-ECGKLGHGLYDATTDPKQIKAWW-----S
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GISGYVCAPPSRVN--GRQYTWIIKPSPEILK
GAS--------------
>MF668284_p134
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVDAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>NC_004688_p144
MLTYSQCQQCNGILQVT--WVGQQ-------THPGCPQTEEELKL---------------
---------------REFVDAIQRGDEAAADKLEAELNRPKP-A-KLGPAALWYAKRAGW
AVFPLVPGEKRPATK----------------------NGFKDATRDEAQIRKWW-----T
ENPNYNIGLPTGRAAGFDVVDIDGPEGMKSLAELGE-GVLPDVHGKVATP---RGFHLYV
AGTDDGNRAGV------RPGIDYR----STGGFVVAVPSVVN--GKQYSWVVRPSPEILK
GAK--------------
>MF919504_p137
MLTYSQCRSCNEILQVT--WVGQE-------THPSCPQTEEELKL---------------
---------------RAFVDAIQRGDESAADKLEAEINKPKP-A-KLGPSALWYAKKAGW
AVFPLVPGEKRPATR----------------------NGFKDATRDGAQIRRWW-----T
ENPNYNIGLPTGKTAGFDVVDVDGPQGVQSLAELGE-GVLPPVHGKVETP---RGFHLYV
LGTADGNRAGV------RPGIDYR----SEGGFVVAVPSIVN--GKRYSWVVRPSPEIMR
A----------------
>NC_022067_p136
MLTYSQCRSCNEILQVT--WVGQE-------THPSCPQTEEELKL---------------
---------------RAFVDAIQRGDESAADKLEAEINKPKP-A-KLGPSALWYAKKAGW
AVFPLVPGEKRPATR----------------------NGFKDATRDGAQIRRWW-----T
ENPNYNIGLPTGKTAGFDVVDVDGPQGVQSLAELGE-GVLPPVHGKVETP---RGFHLYV
LGTADGNRAGV------RPGIDYR----SEGGFVVAVPSIVN--GKRYSWVVRPSPEIMR
A----------------
>NC_023690_p133
MLAFSRCADCGTGMRVL--YVGQE-------THPGCKKTEEEVKL---------------
---------------QEFVEAVQRGDEAAADKLEATINKPKP-A-KLGPSALWYAS-QGW
PVFPLAVGDKLPAIPTAHPKGDPLRGVCKG-ECGKFGHGLYDATTDPAQIRKWW-----G
E-AEYNIGIPTGH--AFDVIDIDGAKGYQSLLELGD-DVFPPIHGKVSTVREDSGEHWYV
LPTGDGNRAG------VRPGIDYR----GAGGYVCVPPSRVG--DKQYAWIIKPSPEILR
KTK--------------
>NC_023744_p77
--MYTTCPTCRDTLELADDWAPAEGAEHRPPVHDGCPPAPLTPVDQLYEN-FR-------
----ELVARIAAPDYKPRMDAGTNMDELNLDALKAKIDQHDQQPPRLGDAALIYAS-WGW
PVFPLRPVGAPC----RNGRRDKCARICQCPKTPATPNGFKDATTDAERIRTYW-----A
KVPGAGIGIATGH--AFDVIDLDLPDGPASWAAMSG---KLPVHGQVLTG--NGGRHLYT
PVTGARNGARI------APGVDYR----GLGGYVVAPPSWLGDHGHKWRWLTKPSPALTG
PSHVNG-----------
>p40310 VI_04151
MILTTPCKICGQDMDTS--WTPDQ---PPPTHHPACDTRPAEEKAHGPHPKLGKLAAAAH
HATLLMAQAAPTSTGSPQWEAFDHACEAVHAAQQAILNADKS------KAAAYYARTLGW
PVFPLKPGGKAPLTP----------------------RGFKDATCDLTQVGAWW-----E
TWPNANIGLPCGE--HFAVIDVDVPYTENQWDALAA---DPNLHVYGLAHTASGGCHAYI
LPEEGPDKNGVN---MFGPKIDYR----TRGGYVVAPYSTRA-DGAPWTWITPPATRIYN
PQEGR------------
>NC_026584_p136
MLTYSQCRSCNEILQVT--WVGQE-------THPSCPQTEEELKL---------------
---------------RAFVDAIQRGDESAADKLEAEINKPKP-A-KLGPSALWYAKKAGW
AVFPLVPGEKRPATR----------------------NGFKDATRDGAQIRRWW-----T
ENPNYNIGLPTGKTAGFDVVDVDGPQGVQSLAELGR-VFYRPYTARLKHP---EGFISTS
WGRPTAIAPASV----RVSTTDQR----A-----------------ASSLPSRPS-----
-----------------
>p17998 VI_00036
------------------------------------------------------------
-----------------------------------------M------RTDPRPTLAAGL
AVFPLPAGAKG--------------------AAPGWS---RQITTDPATV------AGWP
DGVNIGVACRASNVVGLDLDRKHGVDGVDTLRALCA-AARWPWPDTLTVATAH-GLHLYF
RAPTGVVPSSI----GRWPGIDVRAPGRRLGGYLVGPGSVVD--GRPYTIS-RNRPIAAL
PPWLAAKLTDSRVVVTP
>p241807 VI_04140
-----------------------MASPHSPAMDTTTGSHPSTPVDGPAHRSA--------
---------------GASIDRFTRRSPRPGHPYRREDHHTTA------LTHALVAAGRGY
AVIPLTRAKLPAVAS--PHHADQATAPCRG-ACGQLGHGIHDATADPLAVRRLFAAAPWA
TAYGIACGVPPYHLIGIDLDTKHGADGLTALRLLAE-EHHVALPPTVTVRTPSGGHHLYF
SGPPSPPVPNS--AGRLAPGIDIR----GTGGYLVGPGSHTS--RGAYTLT-PGTPEPQP
PPHPPYSTS--------