phrog_5956 is made of 21 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
84.1 228 80


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p142497 no NCBI prot ID no annotation VI_00726 Bacilli_gi_510799013_332654_374213 Viruses.
p144366 no NCBI prot ID no annotation VI_05315 Bacilli_gi_510932048_827932_869296 Viruses.
p360007 no NCBI prot ID no annotation VI_04638 Bacilli_gi_484970370 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p244022 no NCBI prot ID no annotation VI_00791 Bacilli_gi_554764669_0_32411 Viruses.
NC_018085_p57 YP_006488727.1 HNH endonuclease NC_018085 Bacillus phage BtCS33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p253173 no NCBI prot ID no annotation VI_04373 Bacilli_gi_77413447 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p230978 no NCBI prot ID no annotation VI_00822 Bacilli_gi_257431371_0_33726 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p94565 no NCBI prot ID no annotation VI_00468 Bacilli_gi_448879149_252108_297819 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p394644 no NCBI prot ID no annotation VI_04257 Alphaproteobacteria_gi_407977313 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p400254 no NCBI prot ID no annotation VI_04258 Alphaproteobacteria_gi_407977335 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p291103 no NCBI prot ID no annotation VI_06441 Gammaproteobacteria_gi_153901840_0_26994 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p288427 no NCBI prot ID no annotation VI_09929 Gammaproteobacteria_gi_554922277 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_019709_p65 YP_007111702.1 HNH endonuclease NC_019709 Enterobacteria phage mEpX1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Hendrixvirus.
p351335 no NCBI prot ID no annotation VI_12037 Gammaproteobacteria_gi_483600969 Viruses.
p422113 no NCBI prot ID no annotation VI_11418 Gammaproteobacteria_gi_544880810 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p405147 no NCBI prot ID no annotation VI_07975 Gammaproteobacteria_gi_419208689_8812_22297 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p219435 no NCBI prot ID no annotation VI_07486 Gammaproteobacteria_gi_452702422 Viruses.
NC_009820_p75 YP_001469308.1 hypothetical protein NC_009820 Mycobacterium phage Tweety Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
p40460 no NCBI prot ID no annotation VI_06220 Cytophagia_gi_484106105 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MG269973_p13 ATW62216.1 HNH endonuclease MG269973 TM7 phage DolZOral124_53_65 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p204003 no NCBI prot ID no annotation VI_04555 Bacilli_gi_356908088 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2343 64 terminase small subunit head and packaging 3 1.71E-12 2.89
phrog_3173 46 no annotation unknown function 3 4.40E-13 3.48
phrog_17806 5 no annotation unknown function 2 6.94E-13 3.28
phrog_30014 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 96.3 6.5E-05 4-64 / 99-160
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 93.9 0.0063 1-54 / 100-150
phrog_10822 HNH endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00017 6-58 / 99-150
phrog_11604 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 8.8E-07 1-59 / 70-133
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 3.4E-23 1-65 / 26-90
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.6E-07 3-59 / 143-202
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 4.2E-06 1-64 / 11-71
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 99.7 5E-21 1-61 / 57-117
phrog_14736 HNH endonuclease DNA, RNA and nucleotide metabolism 93.1 0.012 7-55 / 33-79
phrog_15103 no annotation unknown function 94.8 0.002 1-59 / 195-256
phrog_16204 no annotation unknown function 92.1 0.024 5-62 / 33-88
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3.6E-05 1-60 / 75-133
phrog_16986 no annotation unknown function 95.8 0.00029 1-60 / 15-71
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 90.6 0.05 22-57 / 9-43
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.8E-06 6-64 / 67-134
phrog_20279 no annotation unknown function 95.5 0.00054 5-59 / 83-145
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0031 3-59 / 13-76
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 8.1E-06 2-58 / 31-81
phrog_22283 no annotation unknown function 92.8 0.015 6-59 / 22-73
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 93.6 0.0082 6-59 / 65-129
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 99.9 1.3E-27 2-79 / 20-113
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 95.1 0.0013 2-59 / 14-67
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.058 22-55 / 127-158
phrog_25862 HNH endonuclease DNA, RNA and nucleotide metabolism 90.7 0.048 4-57 / 87-138
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 6-63 / 60-112
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 4.4E-07 6-62 / 44-111
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 10-66 / 73-126
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 7E-14 1-63 / 23-79
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.4E-08 2-60 / 24-86
phrog_4160 no annotation unknown function 94.2 0.0046 5-60 / 59-120
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 2.8E-05 6-61 / 27-87
phrog_4581 terminase small subunit head and packaging 99.1 1.6E-14 1-63 / 57-114
phrog_5200 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.015 2-61 / 36-91
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 0.0001 2-59 / 19-73
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 99.7 5.5E-21 1-63 / 45-105
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 7.8E-13 4-58 / 3-55
phrog_7275 no annotation unknown function 93.3 0.01 22-64 / 7-47
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.4E-05 1-57 / 36-86
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 9.2E-05 1-55 / 13-67
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 7E-08 1-65 / 63-119
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3.2E-05 2-56 / 23-78
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.4E-07 1-54 / 124-184
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3E-05 2-60 / 106-158
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.0005 2-60 / 106-170
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 90.5 0.054 2-59 / 20-77

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 6.9E-08 47-113 / 77-149
PF13395.5 HNH endonuclease 2.3E-07 66-114 / 1-51
PF01844.22 HNH endonuclease 7.5E-07 66-112 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 1.5E-06 52-114 / 75-136
PF13391.5 HNH endonuclease 2.2E-06 66-115 / 1-46
PF14279.5 HNH endonuclease 3.1E-06 66-114 / 1-45
PF06147.10 Protein of unknown function (DUF968) 1E-05 62-114 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 4E-05 63-114 / 253-296
PF16784.4 Putative HNHc nuclease 0.00073 62-114 / 122-171

Annotations of the NCBI proteins of this PHROG


3:HNH endonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07451 mcrA : 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] no pathways 147 2

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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