phrog_6012 is made of 21 protein sequences and is annotated as "DNA helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
450.57 835 437


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JF937101_p149 AEK09529.1 DnaB-like helicase JF937101 Mycobacterium virus Littlee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_004688_p152 NP_818453.1 gp153 NC_004688 Mycobacterium virus Omega Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
MF133445_p140 ASD53533.1 DnaB-like helicase MF133445 Mycobacterium phage Lucky2013 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919504_p149 ATN88956.1 DNA helicase MF919504 Mycobacterium phage DmpstrDiver Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF668284_p140 ASZ74216.1 DNA helicase MF668284 Mycobacterium phage Squint Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_023738_p131 YP_009018142.1 gp131 NC_023738 Mycobacterium phage Thibault Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_028953_p147 YP_009213364.1 DnaB-like helicase NC_028953 Mycobacterium phage MiaZeal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_022066_p143 YP_008410301.1 DNA helicase NC_022066 Mycobacterium phage Redno2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF072690_p144 ASD50864.1 DnaB-like helicase MF072690 Mycobacterium phage Porcelain Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_026590_p108 YP_009124851.1 RepA-like helicase NC_026590 Mycobacterium phage Gaia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gaiavirus.
NC_028876_p146 YP_009205276.1 RepA NC_028876 Mycobacterium phage Ariel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919512_p146 ATN89859.1 DNA helicase MF919512 Mycobacterium phage Klein Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_022067_p147 YP_008410536.1 DnaB-like helicase NC_022067 Mycobacterium phage Wanda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
JF937090_p149 AEK08205.1 RecA JF937090 Mycobacterium virus Baka Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_023690_p142 YP_009012041.1 gp142 NC_023690 Mycobacterium virus Courthouse Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF957059_p140 AEJ92196.1 DnaB-like helicase JF957059 Mycobacterium virus Optimus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_026584_p147 YP_009124100.1 helicase NC_026584 Mycobacterium phage Minerva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
MF919534_p144 ATS92985.1 DNA helicase MF919534 Mycobacterium phage Superphikiman Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
p216066 no NCBI prot ID no annotation VI_00047 Actinobacteria_gi_484025394 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p393817 no NCBI prot ID no annotation VI_04088 Actinobacteria_gi_317512558 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_009447_p62 YP_001210282.1 BcepGomrgp62 NC_009447 Burkholderia phage BcepGomr Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1492 101 HNH endonuclease DNA, RNA and nucleotide metabolism 11 1.59E-38 28.92
phrog_2147 70 no annotation unknown function 8 2.13E-29 19.79
phrog_10835 9 no annotation unknown function 6 8.53E-30 20.19
phrog_6565 18 no annotation unknown function 6 7.54E-27 17.24
phrog_15096 6 no annotation unknown function 3 5.56E-17 7.38

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.5 0.00064 140-291 / 14-147
phrog_1284 no annotation unknown function 98.1 3.1E-09 125-317 / 22-232
phrog_1366 no annotation unknown function 95.0 0.0015 142-166 / 16-39
phrog_14322 no annotation unknown function 91.7 0.03 140-169 / 194-222
phrog_14685 no annotation unknown function 90.4 0.054 141-169 / 3-30
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 90.5 0.052 140-166 / 38-63
phrog_170 PhoH-like phosphate starvation-inducible other 90.3 0.057 140-164 / 50-74
phrog_1815 guanylate kinase other 92.2 0.022 141-170 / 3-31
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 98.1 3.6E-09 136-354 / 193-421
phrog_2071 ATPase other 91.7 0.031 141-252 / 4-109
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 98.6 2.9E-11 136-354 / 304-550
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 98.4 3.4E-10 129-352 / 22-264
phrog_25693 no annotation unknown function 92.6 0.018 111-298 / 22-220
phrog_2597 DNA primase DNA, RNA and nucleotide metabolism 97.9 1.9E-08 108-314 / 340-544
phrog_2850 no annotation unknown function 99.1 4.1E-14 134-335 / 156-356
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 93.1 0.013 137-288 / 35-183
phrog_296 DNA transposition protein integration and excision 90.3 0.058 139-163 / 90-114
phrog_30286 no annotation unknown function 95.2 0.001 134-408 / 97-392
phrog_3123 no annotation unknown function 99.2 8.4E-15 27-304 / 207-502
phrog_3228 replicative helicase-primase DNA, RNA and nucleotide metabolism 95.7 0.00039 134-333 / 349-544
phrog_3757 no annotation unknown function 92.8 0.015 138-163 / 124-149
phrog_5482 no annotation unknown function 95.9 0.0002 138-306 / 44-235
phrog_6357 no annotation unknown function 97.5 2.2E-07 126-301 / 19-185
phrog_6891 ATPase other 97.0 3.7E-06 140-291 / 34-156
phrog_906 DNA polymerase/primase DNA, RNA and nucleotide metabolism 99.7 1.2E-20 110-291 / 545-721
phrog_97 UvsX-like recombinase other 91.6 0.031 137-290 / 53-206

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09250.10 Bifunctional DNA primase/polymerase, N-terminal 1.7E-12 19-168 / 1-160
PF03796.14 DnaB-like helicase C terminal domain 6E-12 331-550 / 13-255
PF00154.20 recA bacterial DNA recombination protein 3.8E-10 332-536 / 47-248
PF06745.12 KaiC 1.8E-09 331-546 / 13-221
PF08423.10 Rad51 1.2E-08 331-517 / 31-223
PF09807.8 Elongation complex protein 6 3E-08 333-533 / 14-242
PF07088.10 GvpD gas vesicle protein 0.00044 331-363 / 252-287
PF05625.10 PAXNEB protein 1.3E-06 433-518 / 196-275
PF13481.5 AAA domain 3.7E-06 331-485 / 23-185
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 7.1E-05 340-385 / 1-34
PF05621.10 Bacterial TniB protein 0.00014 338-361 / 39-62
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.00034 339-384 / 2-38
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.00037 333-361 / 10-38
PF13479.5 AAA domain 0.00081 337-358 / 2-23
PF05707.11 Zonular occludens toxin (Zot) 0.0009 339-358 / 2-21
PF07693.13 KAP family P-loop domain 0.001 335-362 / 29-56
PF04665.11 Poxvirus A32 protein 0.0014 333-361 / 9-37
PF01637.17 ATPase domain predominantly from Archaea 0.0017 336-362 / 19-45
PF07652.13 Flavivirus DEAD domain 0.0039 336-359 / 3-27
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.0041 340-361 / 1-22
PF04851.14 Type III restriction enzyme, res subunit 0.0055 336-362 / 22-48
PF09820.8 Predicted AAA-ATPase 0.007 337-361 / 31-55

Annotations of the NCBI proteins of this PHROG


6:DnaB-like helicase 6:DNA helicase 2:hypothetical protein 1:RepA 1:RecA 1:helicase 1:COG4983 1:RepA-like helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K02314 dnaB : replicative DNA helicase [EC:3.6.4.12] ko03030 DNA replication
ko04112 Cell cycle - Caulobacter
302 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0002098 tRNA wobble uridine modification
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0008026 ATP-dependent helicase activity
GO:0051188 cofactor biosynthetic process
GO:0003677 DNA binding
GO:0033588 Elongator holoenzyme complex
GO:0009236 cobalamin biosynthetic process
GO:0005524 ATP binding
GO:0006281 DNA repair
GO:0003697 single-stranded DNA binding
GO:0000166 nucleotide binding
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0016787 hydrolase activity

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