phrog_6050 is made of 20 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
89.25 468 59


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031940_p135 YP_009324846.1 hypothetical protein NC_031940 Salmonella phage 118970_sal3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_031940_p74 YP_009324785.1 hypothetical protein NC_031940 Salmonella phage 118970_sal3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p417316 no NCBI prot ID no annotation VI_11656 Gammaproteobacteria_gi_545142876 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p348781 no NCBI prot ID no annotation VI_02143 Gammaproteobacteria_gi_425240590_1_20008 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
KT887557_p23 ALY08146.1 endonuclease KT887557 Pseudomonas phage phi1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p261820 no NCBI prot ID no annotation VI_02713 Gammaproteobacteria_gi_424814883_762787_793595 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p172201 no NCBI prot ID no annotation VI_09047 Gammaproteobacteria_gi_452725248_13395_52192 Viruses.
p184471 no NCBI prot ID no annotation VI_09974 Gammaproteobacteria_gi_555220328_44376_82170 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Salmonella phage ST64B.
p272396 no NCBI prot ID no annotation VI_01892 Gammaproteobacteria_gi_422815473_843850_873534 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p396697 no NCBI prot ID no annotation VI_10030 Gammaproteobacteria_gi_555245893 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p35187 no NCBI prot ID no annotation VI_00711 Bacilli_gi_507055493_2793767_2856861 Viruses.
p63026 no NCBI prot ID no annotation VI_00411 Bacilli_gi_423399602_2939316_2990500 Viruses.
KY514263_p62 ARB11536.1 HNH endonuclease KY514263 Pectobacterium phage vB_PatM_CB7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Certrevirus; unclassified Certrevirus.
NC_023717_p72 YP_009015034.1 hypothetical protein NC_023717 Cronobacter phage CR9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Certrevirus.
p16182 no NCBI prot ID no annotation VI_00865 Bacilli_gi_514961984 Viruses.
p13553 no NCBI prot ID no annotation VI_08594 Gammaproteobacteria_gi_484317654 Viruses.
KY065489_p27 APD23716.1 HNH endonuclease domain-containing protein KY065489 Streptococcus phage IPP51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF347637_p110 ASR77592.1 hypothetical protein MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.
KX774321_p138 AOZ63726.1 HNH endonuclease KX774321 Rhodococcus phage Weasels2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Weaselvirus; Rhodococcus virus Weasel.
NC_023719_p149 YP_009015460.1 gp157 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_83 1008 terminase small subunit head and packaging 8 1.37E-19 9.99
phrog_32515 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.6 4.2E-11 5-55 / 101-154
phrog_10822 HNH endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00016 3-50 / 97-145
phrog_11604 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00013 4-55 / 74-132
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 98.8 5.3E-12 3-55 / 29-83
phrog_12400 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.0003 7-54 / 31-87
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00073 17-54 / 52-89
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 7.2E-09 3-55 / 144-201
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 2.7E-10 4-56 / 15-66
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 3.6E-14 3-56 / 60-115
phrog_15103 no annotation unknown function 96.0 0.00019 6-52 / 201-252
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0021 4-56 / 130-184
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 1E-09 3-54 / 78-130
phrog_16986 no annotation unknown function 98.2 1.2E-09 1-55 / 16-69
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 1.8E-10 20-54 / 8-43
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 1E-05 5-56 / 67-130
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 2.9E-11 2-55 / 13-75
phrog_22048 HNH endonuclease DNA, RNA and nucleotide metabolism 91.5 0.034 7-54 / 2-48
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 3.5E-13 5-56 / 35-82
phrog_22283 no annotation unknown function 98.1 4.7E-09 7-54 / 24-71
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.011 4-56 / 64-129
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 98.5 1.5E-10 3-54 / 22-89
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.6E-05 17-54 / 87-124
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2E-05 6-54 / 90-160
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.013 3-54 / 42-107
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.9E-06 18-53 / 33-68
phrog_29143 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0023 6-54 / 20-74
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 5E-05 4-51 / 59-103
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 1.2E-05 5-56 / 44-108
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.8E-06 5-55 / 72-118
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 3.3E-14 3-57 / 26-76
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0027 6-57 / 20-78
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 7.8E-16 5-56 / 28-85
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.7E-05 3-55 / 25-84
phrog_4581 terminase small subunit head and packaging 98.5 9E-11 4-56 / 61-110
phrog_4590 no annotation unknown function 94.5 0.0029 18-53 / 49-84
phrog_5104 no annotation unknown function 95.0 0.0014 7-56 / 146-199
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 1.7E-13 4-55 / 22-72
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 99.5 1.3E-17 3-57 / 48-102
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 4.9E-13 3-55 / 4-58
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 96.5 3.1E-05 18-43 / 20-45
phrog_7275 no annotation unknown function 96.2 9.7E-05 20-57 / 6-43
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.8E-05 3-53 / 39-85
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 4-53 / 17-68
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 2E-14 4-57 / 67-115
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0032 3-51 / 25-76
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 5.9E-08 2-51 / 126-184
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 2.5E-13 3-56 / 108-157
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 1.1E-06 6-55 / 21-75
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 1.1E-08 4-58 / 109-171
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.4E-05 5-55 / 39-88
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 3.8E-13 6-56 / 27-77

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 2.1E-08 285-347 / 70-135
PF13395.5 HNH endonuclease 4.6E-06 304-348 / 1-51
PF01844.22 HNH endonuclease 1.1E-05 304-346 / 1-46
PF05315.10 ICEA Protein 4E-05 288-347 / 80-149
PF13391.5 HNH endonuclease 3.6E-05 304-348 / 1-45
PF14279.5 HNH endonuclease 8.8E-05 304-348 / 1-45
PF06147.10 Protein of unknown function (DUF968) 0.00018 300-348 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.0062 301-349 / 253-297
PF16784.4 Putative HNHc nuclease 0.0072 299-347 / 121-170

Annotations of the NCBI proteins of this PHROG


5:hypothetical protein 2:HNH endonuclease 1:endonuclease 1:HNH endonuclease domain-containing protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07451 mcrA : 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] no pathways 133 7

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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