phrog_6223 is made of 19 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
75.16 109 76


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p192116 no NCBI prot ID no annotation VI_09192 Gammaproteobacteria_gi_452734332 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p6992 no NCBI prot ID no annotation VI_09232 Gammaproteobacteria_gi_452736179 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p15487 no NCBI prot ID no annotation VI_09323 Gammaproteobacteria_gi_452741421 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p12995 no NCBI prot ID no annotation VI_09223 Gammaproteobacteria_gi_452735834_8512_93839 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p14651 no NCBI prot ID no annotation VI_09177 Gammaproteobacteria_gi_452733007 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p24922 no NCBI prot ID no annotation VI_09535 Gammaproteobacteria_gi_481021442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p322763 no NCBI prot ID no annotation VI_09258 Gammaproteobacteria_gi_452737991_1796_24904 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p420738 no NCBI prot ID no annotation VI_04244 Alphaproteobacteria_gi_484352444 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p114656 no NCBI prot ID no annotation VI_04236 Alphaproteobacteria_gi_484351531_3486_47539 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p192068 no NCBI prot ID no annotation VI_04240 Alphaproteobacteria_gi_484351963 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p37628 no NCBI prot ID no annotation VI_04229 Alphaproteobacteria_gi_484349863 Viruses.
p336069 no NCBI prot ID no annotation VI_08548 Gammaproteobacteria_gi_484236376 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p352958 no NCBI prot ID no annotation VI_08572 Gammaproteobacteria_gi_484247659 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p399906 no NCBI prot ID no annotation VI_08558 Gammaproteobacteria_gi_484238593 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p358750 no NCBI prot ID no annotation VI_08544 Gammaproteobacteria_gi_484235442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p115427 no NCBI prot ID no annotation VI_09903 Gammaproteobacteria_gi_545908410 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p71424 no NCBI prot ID no annotation VI_03103 Gammaproteobacteria_gi_553777758_1058139_1107563 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p19011 no NCBI prot ID no annotation VI_09479 Gammaproteobacteria_gi_425739195 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KU197014_p38 AMW36154.1 hypothetical protein KU197014 Xanthomonas phage XAJ2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12214 8 no annotation unknown function 8 0 1000
phrog_617 226 major head protein head and packaging 3 7.03E-12 2.27

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11138 no annotation unknown function 95.1 0.0013 3-43 / 92-133
phrog_11145 DNA binding protein DNA, RNA and nucleotide metabolism 93.0 0.013 18-42 / 2-26
phrog_1124 transcriptional regulator transcription regulation 92.6 0.018 16-41 / 18-43
phrog_11376 no annotation unknown function 93.3 0.01 9-40 / 50-81
phrog_1157 transposase integration and excision 96.0 0.00019 6-48 / 6-48
phrog_1190 RNA polymerase sigma factor transcription regulation 91.2 0.039 2-37 / 137-173
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 92.6 0.018 14-41 / 155-182
phrog_12823 no annotation unknown function 93.9 0.0061 14-44 / 25-55
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 96.9 6E-06 3-51 / 5-53
phrog_1368 transcriptional regulator transcription regulation 94.7 0.0023 7-43 / 18-54
phrog_1373 transcriptional regulator transcription regulation 97.4 4.7E-07 14-41 / 41-68
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 96.8 8.2E-06 14-58 / 20-63
phrog_1468 transcriptional repressor transcription regulation 94.9 0.0018 14-51 / 17-54
phrog_147 transcriptional regulator transcription regulation 90.9 0.044 3-53 / 3-50
phrog_151 transposase integration and excision 91.4 0.035 14-42 / 20-48
phrog_1529 no annotation unknown function 95.6 0.00046 6-59 / 7-59
phrog_1590 no annotation unknown function 90.1 0.062 7-53 / 55-98
phrog_1728 transcriptional regulator transcription regulation 91.2 0.038 14-40 / 13-39
phrog_1740 RNA polymerase sigma factor transcription regulation 95.0 0.0015 2-39 / 126-164
phrog_18104 transcriptional regulator transcription regulation 96.3 7.2E-05 15-59 / 11-54
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0024 15-40 / 68-93
phrog_2119 no annotation unknown function 95.4 0.00072 2-46 / 12-56
phrog_21612 RNA polymerase sigma factor transcription regulation 90.4 0.055 14-63 / 187-239
phrog_2308 no annotation unknown function 92.9 0.014 3-39 / 1-38
phrog_2328 transcriptional repressor transcription regulation 93.7 0.0072 7-45 / 16-56
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.1 0.0012 14-47 / 34-67
phrog_2418 no annotation unknown function 91.4 0.036 17-38 / 56-77
phrog_2439 transcriptional regulator transcription regulation 93.6 0.0079 14-53 / 16-54
phrog_2538 terminase small subunit head and packaging 94.0 0.0053 14-40 / 16-42
phrog_268 no annotation unknown function 93.4 0.0099 14-39 / 14-38
phrog_2967 transcriptional regulator transcription regulation 94.7 0.0023 14-44 / 18-49
phrog_296 DNA transposition protein integration and excision 95.5 0.00062 14-63 / 11-60
phrog_32768 no annotation unknown function 91.9 0.027 8-46 / 11-51
phrog_3282 sigma factor transcription regulation 94.0 0.0057 3-36 / 18-51
phrog_34939 no annotation unknown function 94.2 0.0046 4-56 / 7-61
phrog_351 RNA polymerase sigma factor transcription regulation 95.6 0.00045 3-43 / 176-220
phrog_3557 transcriptional regulator transcription regulation 91.4 0.035 7-43 / 14-51
phrog_357 transcriptional repressor transcription regulation 90.0 0.063 14-39 / 21-46
phrog_35 transcriptional repressor transcription regulation 95.3 0.00085 6-47 / 4-44
phrog_3638 CII-like transcriptional activator transcription regulation 91.2 0.039 20-53 / 28-61
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.1 0.0012 17-51 / 20-55
phrog_36 transcriptional regulator transcription regulation 91.7 0.03 5-39 / 92-127
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.011 14-36 / 76-98
phrog_3910 transcriptional regulator transcription regulation 95.2 0.0011 14-36 / 76-98
phrog_3949 transcriptional repressor transcription regulation 93.0 0.013 19-48 / 30-59
phrog_3 transcriptional repressor transcription regulation 96.9 5.4E-06 14-49 / 13-46
phrog_409 transcriptional regulator transcription regulation 90.9 0.045 16-45 / 10-37
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 95.3 0.0009 8-39 / 14-42
phrog_4291 RNA-dependent RNA polymerase DNA, RNA and nucleotide metabolism 91.2 0.039 16-40 / 882-906
phrog_4583 transcriptional repressor transcription regulation 95.1 0.0012 7-42 / 11-48
phrog_4646 transposase integration and excision 95.1 0.0012 3-64 / 7-78
phrog_4779 transcriptional regulator transcription regulation 96.4 5.2E-05 14-46 / 11-43
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.9 0.00024 13-42 / 75-104
phrog_5229 no annotation unknown function 92.9 0.015 16-39 / 80-103
phrog_5301 transcriptional repressor transcription regulation 95.5 0.00058 13-54 / 19-61
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.7 0.049 17-47 / 20-49
phrog_5536 no annotation unknown function 95.2 0.0011 14-39 / 18-43
phrog_57 terminase small subunit head and packaging 90.6 0.051 17-65 / 2-59
phrog_5823 transcriptional regulator transcription regulation 95.5 0.00052 7-54 / 5-54
phrog_597 DNA binding protein DNA, RNA and nucleotide metabolism 90.8 0.046 14-50 / 11-45
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 93.5 0.0092 17-42 / 111-136
phrog_6081 no annotation unknown function 91.9 0.028 3-38 / 60-96
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00019 8-41 / 28-58
phrog_6288 no annotation unknown function 90.7 0.048 14-48 / 21-56
phrog_638 transcriptional regulator transcription regulation 93.5 0.0092 9-50 / 5-48
phrog_645 Rnase E DNA, RNA and nucleotide metabolism 90.7 0.049 14-44 / 32-62
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 95.3 0.0008 14-48 / 65-99
phrog_66 excisionase and transcriptional regulator integration and excision 92.4 0.02 17-42 / 9-35
phrog_6831 transcriptional regulator transcription regulation 99.2 5.1E-15 6-65 / 3-64
phrog_686 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.2 0.00099 15-44 / 35-64
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0038 14-42 / 41-69
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.9 5.4E-06 14-57 / 26-70
phrog_7241 transcriptional regulator transcription regulation 96.7 1.5E-05 10-47 / 65-105
phrog_725 CII-like regulator transcription regulation 96.4 4.1E-05 6-40 / 16-50
phrog_7344 terminase small subunit head and packaging 90.1 0.061 11-39 / 20-48
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 90.9 0.045 14-36 / 15-37
phrog_7676 no annotation unknown function 94.7 0.0025 3-38 / 2-37
phrog_769 transcriptional repressor transcription regulation 93.6 0.0085 7-39 / 14-47
phrog_8038 no annotation unknown function 96.8 8.4E-06 18-61 / 14-58
phrog_836 late transcriptional activator transcription regulation 90.1 0.061 15-44 / 107-136
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00014 8-61 / 6-61
phrog_8794 sigma factor transcription regulation 90.7 0.049 15-39 / 19-43
phrog_8 transcriptional regulator transcription regulation 96.7 1.5E-05 14-57 / 11-51
phrog_9103 transcriptional repressor transcription regulation 92.6 0.018 19-52 / 22-56
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.5 0.0031 14-45 / 14-45
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.3 0.021 7-38 / 8-39

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 1.4E-07 33-98 / 8-80
PF13744.5 Helix-turn-helix domain 6.7E-07 34-91 / 17-76
PF05339.10 Protein of unknown function (DUF739) 1.1E-06 43-93 / 13-62
PF01381.21 Helix-turn-helix 1.5E-06 43-91 / 6-53
PF13413.5 Helix-turn-helix domain 2.4E-06 43-91 / 6-59
PF14590.5 Domain of unknown function (DUF4447) 4.7E-06 36-91 / 8-67
PF13443.5 Cro/C1-type HTH DNA-binding domain 4.9E-06 43-93 / 7-59
PF13560.5 Helix-turn-helix domain 6.2E-06 43-92 / 11-62
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 6.8E-06 44-92 / 9-56
PF04645.11 Protein of unknown function, DUF603 8.9E-06 34-84 / 6-60
PF12844.6 Helix-turn-helix domain 9E-06 43-92 / 9-57
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.2E-05 43-93 / 79-127
PF08965.9 Domain of unknown function (DUF1870) 1.2E-05 43-86 / 11-55
PF05269.10 Bacteriophage CII protein 2.8E-05 43-93 / 20-67
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 4.3E-05 47-91 / 9-52
PF08667.9 BetR domain 4.4E-05 36-92 / 6-67
PF00356.20 Bacterial regulatory proteins, lacI family 9E-05 48-86 / 1-38
PF12116.7 Stage III sporulation protein D 9.4E-05 45-90 / 18-63
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00021 43-87 / 123-166
PF10654.8 Protein of unknown function (DUF2481) 0.00026 43-71 / 77-105
PF14549.5 DNA-binding transcriptional regulator Cro 0.00031 43-91 / 7-50
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00063 36-87 / 8-64
PF13693.5 Winged helix-turn-helix DNA-binding 0.00099 43-92 / 12-57
PF08535.9 KorB domain 0.0013 45-70 / 2-27
PF07506.10 RepB plasmid partitioning protein 0.0019 43-70 / 18-45
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.003 44-71 / 11-38
PF04552.12 Sigma-54, DNA binding domain 0.0033 44-70 / 46-72
PF00376.22 MerR family regulatory protein 0.0043 48-71 / 1-24
PF01371.18 Trp repressor protein 0.0049 44-83 / 46-84
PF02376.14 CUT domain 0.0062 36-88 / 8-60

Annotations of the NCBI proteins of this PHROG


1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0019069 viral capsid assembly
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006355 regulation of transcription, DNA-templated
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 DNA binding transcription factor activity
GO:0005524 ATP binding
GO:0005634 nucleus

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