phrog_6254 is made of 19 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
144.21 237 152


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_018859_p49 YP_006908900.1 homing endonuclease NC_018859 Escherichia phage ECBP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Kuravirus.
MG603697_p146 AUG88510.1 hypothetical protein MG603697 Vibrio phage Vp_R1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
NC_007808_p14 YP_001294607.1 hypothetical protein ORF014 NC_007808 Pseudomonas phage PA11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
MG676466_p39 AUG88550.1 putative endonuclease MG676466 Pseudomonas phage TC6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
NC_011045_p26 YP_002003959.1 endonuclease NC_011045 Enterobacteria phage 13a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus.
NC_007456_p20 YP_338109.1 homing endonuclease NC_007456 Enterobacteria phage K1F Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Kayfunavirus; Escherichia virus K1F.
NC_031258_p45 YP_009303694.1 hypothetical protein NC_031258 Salmonella phage BP12A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Salmonella virus BP12A.
MG832642_p5 AUV62629.1 hypothetical protein MG832642 Escherichia phage HZ2R8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus; Escherichia virus HZ2R8.
NC_027387_p7 YP_009152458.1 hypothetical protein NC_027387 Escherichia phage CICC 80001 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus; Escherichia virus CICC80001.
NC_023715_p44 YP_009014865.1 hypothetical protein NC_023715 Yersinia phage Yep-phi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Yersinia virus Yepf.
NC_008694_p43 YP_919025.1 Conserved phage & prophage protein NC_008694 Yersinia phage Berlin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Yersinia virus Berlin.
NC_011038_p46 YP_002003358.1 gp7.7 homolog NC_011038 Yersinia phage Yepe2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Yersinia virus Yepe2.
NC_015271_p46 YP_004306697.1 predicted endonuclease NC_015271 Salmonella phage Vi06 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus; Salmonella virus Vi06.
NC_011045_p54 YP_002003987.1 gp19.4 NC_011045 Enterobacteria phage 13a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teseptimavirus.
KY084243_p49 APD19661.1 HNH homing endonuclease KY084243 Pectobacterium phage PP74 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Pectobacterium virus PP74.
MG972768_p8 AVP40056.1 hypothetical protein MG972768 Klebsiella phage myPSH1235 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Slopekvirinae; Drulisvirus; Klebsiella virus myPSH1235.
NC_012662_p13 YP_002875637.1 hypothetical protein NC_012662 Vibrio phage VP93 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Maculvirus; Vibrio virus VP93.
NC_016163_p108 YP_004934341.1 hypothetical protein NC_016163 Yersinia phage phiR1-37 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_023863_p40 YP_009021706.1 HNH endonuclease NC_023863 Vibrio phage CHOED Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_17 2050 DNA polymerase DNA, RNA and nucleotide metabolism 8 1.91E-16 6.84
phrog_38 1538 terminase large subunit head and packaging 7 2.64E-15 5.7
phrog_2193 69 no annotation unknown function 4 9.94E-16 6.12
phrog_30163 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10495 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 2.8E-05 48-85 / 19-56
phrog_1492 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 2.2E-09 11-92 / 36-126
phrog_1872 endonuclease DNA, RNA and nucleotide metabolism 99.9 3.7E-28 9-92 / 22-107
phrog_1891 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.5E-05 20-82 / 102-166
phrog_3593 HNH endonuclease DNA, RNA and nucleotide metabolism 99.6 1.9E-20 11-119 / 52-146
phrog_4578 HNH endonuclease DNA, RNA and nucleotide metabolism 91.5 0.034 48-87 / 3-42
phrog_4842 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 2.6E-10 11-74 / 74-137
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 9.8E-12 6-148 / 15-134
phrog_826 HNH endonuclease DNA, RNA and nucleotide metabolism 99.7 5.5E-22 9-85 / 17-97
phrog_959 HNH endonuclease DNA, RNA and nucleotide metabolism 95.5 0.0006 19-88 / 36-105
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 4.3E-09 9-85 / 13-98

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05551.10 Zinc-binding loop region of homing endonuclease 1.7E-11 21-92 / 1-79
PF13392.5 HNH endonuclease 2.4E-10 46-89 / 2-44
PF07453.12 NUMOD1 domain 0.0021 132-154 / 18-40
PF06413.10 Neugrin 0.0024 113-163 / 11-58

Annotations of the NCBI proteins of this PHROG


8:hypothetical protein 3:homing endonuclease 2:endonuclease 1:HNH endonuclease 1:predicted endonuclease 1:gp19.4 1:HNH homing endonuclease 1:Conserved phage & prophage protein 1:gp7.7 homolog

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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