phrog_6267 is made of 19 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
99.84 121 101


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MG770213_p44 AUV60547.1 hypothetical protein MG770213 Mycobacterium phage OldBen Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KR997931_p55 AKU45142.1 HTH DNA-binding domain protein KR997931 Mycobacterium phage Girafales Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028751_p54 YP_009194578.1 HTH DNA-binding domain protein NC_028751 Mycobacterium phage Quico Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_011289_p47 YP_002241834.1 gp47 NC_011289 Mycobacterium virus Ramsey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_009820_p46 YP_001469279.2 HTH DNA binding domain protein NC_009820 Mycobacterium phage Tweety Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_023580_p48 YP_009007515.1 hypothetical protein NC_023580 Mycobacterium phage Saal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG962361_p51 AVO24550.1 CRO protein MG962361 Mycobacterium phage Alexphander Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MH051257_p44 AVR77284.1 hypothetical protein MH051257 Mycobacterium phage OwlsT2W Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_026595_p46 YP_009125225.1 CRO protein NC_026595 Mycobacterium phage Hades Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JN859129_p43 AER14089.1 HTH domain protein JN859129 Mycobacterium virus Dotproduct Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028823_p42 YP_009200669.1 HTH domain protein NC_028823 Mycobacterium phage Bipolar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_026593_p51 YP_009125044.1 hypothetical protein NC_026593 Mycobacterium phage BuzzLyseyear Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_022056_p47 YP_008409111.1 hypothetical protein NC_022056 Mycobacterium phage Hamulus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028889_p56 YP_009206774.1 HTH DNA-binding domain protein NC_028889 Mycobacterium phage Florinda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023728_p50 YP_009016940.1 gp50 NC_023728 Mycobacterium virus Deadp Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_021334_p38 YP_008059939.1 putative helix-turn-helix XRE-family like protein NC_021334 Mycobacterium phage WIVsmall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_021301_p46 YP_008051172.1 HTH DNA binding domain protein NC_021301 Mycobacterium phage SiSi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_014901_p49 YP_004123871.1 gp49 NC_014901 Mycobacterium phage Wee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_023746_p44 YP_009018920.1 gp44 NC_023746 Mycobacterium virus Gumbie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_130 726 anti-repressor Ant transcription regulation 13 5.05E-40 30.42
phrog_15279 6 no annotation unknown function 4 1.42E-23 13.97

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1373 transcriptional regulator transcription regulation 93.8 0.0067 33-85 / 36-87
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 90.4 0.055 37-74 / 19-55
phrog_1702 transcriptional repressor transcription regulation 96.6 1.9E-05 31-93 / 16-80
phrog_2967 transcriptional regulator transcription regulation 94.9 0.0018 31-91 / 11-71
phrog_35 transcriptional repressor transcription regulation 95.0 0.0015 44-91 / 15-64
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.9 1.3E-12 26-90 / 4-69
phrog_3949 transcriptional repressor transcription regulation 93.0 0.013 44-88 / 30-73
phrog_3 transcriptional repressor transcription regulation 91.2 0.039 32-82 / 7-55
phrog_4779 transcriptional regulator transcription regulation 90.2 0.059 32-66 / 5-38
phrog_6223 transcriptional repressor transcription regulation 90.0 0.063 44-77 / 19-53
phrog_769 transcriptional repressor transcription regulation 93.3 0.01 32-91 / 16-71
phrog_8 transcriptional regulator transcription regulation 96.6 2.5E-05 32-91 / 5-61
phrog_9103 transcriptional repressor transcription regulation 96.2 8.4E-05 26-82 / 4-60
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.9 0.0019 32-68 / 8-43

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13744.5 Helix-turn-helix domain 1.5E-07 39-103 / 15-79
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 4.6E-07 39-104 / 7-77
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 5.6E-07 48-107 / 4-62
PF01381.21 Helix-turn-helix 1.2E-06 49-101 / 3-54
PF05339.10 Protein of unknown function (DUF739) 1.6E-06 45-103 / 6-63
PF14590.5 Domain of unknown function (DUF4447) 1.9E-06 42-105 / 7-72
PF12844.6 Helix-turn-helix domain 2.1E-06 48-105 / 5-61
PF13413.5 Helix-turn-helix domain 4.1E-06 49-100 / 3-59
PF04645.11 Protein of unknown function, DUF603 6.8E-06 40-93 / 5-60
PF08667.9 BetR domain 1E-05 42-106 / 5-72
PF13560.5 Helix-turn-helix domain 1.3E-05 44-102 / 3-63
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.3E-05 43-103 / 70-128
PF05269.10 Bacteriophage CII protein 2.1E-05 48-105 / 16-70
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.1E-05 58-105 / 13-62
PF13693.5 Winged helix-turn-helix DNA-binding 8.9E-05 46-106 / 6-62
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 9.5E-05 58-106 / 10-58
PF08965.9 Domain of unknown function (DUF1870) 0.00011 44-84 / 3-44
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00092 44-95 / 115-165
PF02376.14 CUT domain 0.0011 42-106 / 7-69
PF12116.7 Stage III sporulation protein D 0.0012 54-98 / 18-62
PF00356.20 Bacterial regulatory proteins, lacI family 0.0015 59-85 / 2-28
PF14549.5 DNA-binding transcriptional regulator Cro 0.0032 58-102 / 11-52
PF10654.8 Protein of unknown function (DUF2481) 0.0052 52-80 / 77-104

Annotations of the NCBI proteins of this PHROG


7:hypothetical protein 3:HTH DNA-binding domain protein 2:CRO protein 2:HTH DNA binding domain protein 2:HTH domain protein 1:helix-turn-helix XRE-family like protein 1:HTH DNA binding 1:HTH domain

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated

Loading in process