phrog_6380 is made of 19 protein sequences and is annotated as "DNA methyltransferase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
365.63 547 338


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p166548 no NCBI prot ID no annotation VI_05253 Bacilli_gi_459819101_64627_104037 Viruses.
p192421 no NCBI prot ID no annotation VI_07171 Gammaproteobacteria_gi_417241141 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p160916 no NCBI prot ID no annotation VI_00467 Bacilli_gi_448879146_1659265_1699117 Viruses.
p103414 no NCBI prot ID no annotation VI_05429 Bacilli_gi_565866318 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Streptococcus phage EJ-1.
p243302 no NCBI prot ID no annotation VI_01361 Fusobacteriia_gi_547450323_34938_67437 Viruses.
MG696115_p72 AUM58700.1 methyltransferase MG696115 Plesiomonas phage phiP4-7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p349694 no NCBI prot ID no annotation VI_07363 Gammaproteobacteria_gi_417846219 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p276631 no NCBI prot ID no annotation VI_07364 Gammaproteobacteria_gi_417846251 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_028743_p36 YP_009193587.1 hypothetical protein NC_028743 Mannheimia phage vB_MhS_587AP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p145142 no NCBI prot ID no annotation VI_00601 Bacilli_gi_502327608_33351_74643 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065457_p29 APD21998.1 type I restriction-modification system, DNA-methyltransferase subunit M KY065457 Streptococcus phage IPP16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p185528 no NCBI prot ID no annotation VI_04363 Bacilli_gi_223933165_0_37690 Viruses.
p23173 no NCBI prot ID no annotation VI_04007 Negativicutes_gi_312899164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p320555 no NCBI prot ID no annotation VI_05798 Clostridia_gi_402838822 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p321330 no NCBI prot ID no annotation VI_06335 Fusobacteriia_gi_421501288 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p50449 no NCBI prot ID no annotation VI_04016 Negativicutes_gi_546349956_16649_73610 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p50453 no NCBI prot ID no annotation VI_04016 Negativicutes_gi_546349956_16649_73610 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KY065464_p25 APD22366.1 type I restriction-modification system, DNA-methyltransferase subunit M KY065464 Streptococcus phage IPP23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p282838 no NCBI prot ID no annotation VI_06187 Clostridia_gi_553310853 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2668 53 no annotation unknown function 4 1.89E-16 6.84
phrog_26128 3 no annotation unknown function 3 0 1000
phrog_884 163 no annotation unknown function 3 5.40E-11 1.39
phrog_20972 4 no annotation unknown function 2 2.15E-13 3.79

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10089 DarB-like antirestriction moron, auxiliary metabolic gene and host takeover 93.7 0.0073 6-217 / 1557-1753(4381)
phrog_10691 no annotation unknown function 96.3 5.8E-05 8-221 / 991-1168(1276)
phrog_1071 DNA methyltransferase other 99.9 3.8E-27 1-114 / 55-188
phrog_11358 no annotation unknown function 97.1 3E-06 15-217 / 1911-2081(3731)
phrog_11801 DNA methyltransferase other 98.2 2.2E-09 11-216 / 90-281
phrog_13671 DNA methyltransferase other 97.9 1.8E-08 7-228 / 326-551
phrog_14586 no annotation unknown function 93.8 0.0069 108-219 / 2-110
phrog_15406 DNA methyltransferase other 96.8 1.2E-05 17-215 / 687-850
phrog_1600 DNA methyltransferase other 97.9 2.2E-08 11-190 / 26-208
phrog_16674 DNA methyltransferase other 91.4 0.035 108-217 / 690-804
phrog_1685 no annotation unknown function 97.1 2.7E-06 11-217 / 87-277
phrog_18947 no annotation unknown function 95.3 0.00092 15-217 / 570-739
phrog_22901 no annotation unknown function 95.1 0.0011 9-221 / 630-809
phrog_23041 no annotation unknown function 95.1 0.0013 35-121 / 114-188
phrog_24008 helicase DNA, RNA and nucleotide metabolism 98.0 6.5E-09 11-216 / 71-251
phrog_2713 no annotation unknown function 100.0 3.2E-48 11-297 / 194-513
phrog_29705 no annotation unknown function 92.3 0.022 35-210 / 9-164
phrog_3008 DNA methyltransferase other 94.8 0.0019 16-67 / 11-63
phrog_31645 no annotation unknown function 96.3 6.6E-05 56-216 / 529-709
phrog_34860 no annotation unknown function 99.2 1.4E-14 11-228 / 175-415
phrog_3820 DNA methyltransferase other 98.7 1.2E-11 11-216 / 47-229
phrog_4752 tRNA methyltransferase other 93.0 0.013 22-154 / 42-164
phrog_5172 no annotation unknown function 95.1 0.0012 11-214 / 6-165
phrog_5696 no annotation unknown function 97.7 8.7E-08 8-88 / 103-205
phrog_6263 DNA methyltransferase other 98.0 6.2E-09 13-214 / 399-559
phrog_799 DNA methyltransferase other 97.6 1.3E-07 6-173 / 8-123
phrog_9133 no annotation unknown function 99.5 1.5E-18 10-214 / 83-252
phrog_9793 no annotation unknown function 94.8 0.0021 15-214 / 606-771

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF02384.15 N-6 DNA Methylase 5.5E-19 69-350 / 25-311
PF13489.5 Methyltransferase domain 3.4E-08 88-258 / 20-185
PF05175.13 Methyltransferase small domain 5.2E-08 89-217 / 31-139
PF02390.16 Putative methyltransferase 1.4E-07 90-217 / 2-126
PF05891.11 AdoMet dependent proline di-methyltransferase 1.7E-07 88-261 / 54-196
PF12147.7 Putative methyltransferase 2E-07 88-260 / 130-290
PF05971.11 Protein of unknown function (DUF890) 3.3E-07 89-134 / 103-148
PF07091.10 Ribosomal RNA methyltransferase (FmrO) 4.1E-07 89-262 / 102-241
PF06080.11 Protein of unknown function (DUF938) 4.1E-07 89-259 / 27-189
PF08003.10 Protein of unknown function (DUF1698) 4.4E-07 88-260 / 115-266
PF01209.17 ubiE/COQ5 methyltransferase family 5.4E-07 92-217 / 59-173
PF05185.15 PRMT5 arginine-N-methyltransferase 5.7E-07 88-212 / 58-169
PF01234.16 NNMT/PNMT/TEMT family 6.9E-07 89-261 / 56-237
PF11599.7 RRNA methyltransferase AviRa 7.5E-07 88-134 / 48-96
PF01739.17 CheR methyltransferase, SAM binding domain 7.6E-07 89-217 / 33-175
PF00891.17 O-methyltransferase 7.9E-07 88-216 / 74-179
PF05401.10 Nodulation protein S (NodS) 8.5E-07 88-262 / 42-180
PF01861.15 Protein of unknown function DUF43 9E-07 89-216 / 43-147
PF02353.19 Mycolic acid cyclopropane synthetase 9.6E-07 88-217 / 60-162
PF10294.8 Lysine methyltransferase 9.9E-07 88-217 / 44-155
PF05724.10 Thiopurine S-methyltransferase (TPMT) 1E-06 88-261 / 37-195
PF07942.11 N2227-like protein 1.1E-06 88-262 / 56-240
PF13847.5 Methyltransferase domain 1.2E-06 89-215 / 3-117
PF05219.11 DREV methyltransferase 1.3E-06 89-260 / 90-235
PF03492.14 SAM dependent carboxyl methyltransferase 1.7E-06 89-132 / 13-71
PF11968.7 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 1.9E-06 88-260 / 51-182
PF06325.12 Ribosomal protein L11 methyltransferase (PrmA) 2.4E-06 89-215 / 172-271
PF08123.12 Histone methylation protein DOT1 2.7E-06 88-258 / 41-186
PF03602.14 Conserved hypothetical protein 95 2.9E-06 88-219 / 36-144
PF04378.12 Ribosomal RNA large subunit methyltransferase D, RlmJ 3.6E-06 89-214 / 60-165
PF03848.13 Tellurite resistance protein TehB 3.5E-06 88-216 / 29-134
PF01564.16 Spermine/spermidine synthase domain 3.6E-06 89-215 / 18-131
PF12847.6 Methyltransferase domain 5.4E-06 89-134 / 14-59
PF07021.11 Methionine biosynthesis protein MetW 6E-06 89-261 / 13-165
PF02527.14 rRNA small subunit methyltransferase G 6.8E-06 92-215 / 54-148
PF04672.11 S-adenosyl methyltransferase 8.4E-06 89-219 / 69-191
PF03141.15 Putative S-adenosyl-L-methionine-dependent methyltransferase 4.5E-05 89-216 / 354-462
PF09243.9 Mitochondrial small ribosomal subunit Rsm22 9.5E-06 89-208 / 34-134
PF10672.8 S-adenosylmethionine-dependent methyltransferase 9.7E-06 70-215 / 107-237
PF01269.16 Fibrillarin 1.2E-05 89-261 / 72-210
PF12692.6 S-adenosyl-L-methionine methyltransferase 1.4E-05 89-217 / 28-133
PF08242.11 Methyltransferase domain 1.4E-05 94-211 / 1-100
PF13679.5 Methyltransferase domain 1.5E-05 88-134 / 24-76
PF01596.16 O-methyltransferase 1.6E-05 77-217 / 36-157
PF02475.15 Met-10+ like-protein 1.7E-05 89-213 / 100-200
PF10017.8 Histidine-specific methyltransferase, SAM-dependent 1.9E-05 89-217 / 62-176
PF01170.17 Putative RNA methylase family UPF0020 1.9E-05 78-135 / 17-113
PF08241.11 Methyltransferase domain 1.9E-05 94-213 / 1-95
PF03291.15 mRNA capping enzyme 2E-05 89-219 / 59-177
PF00398.19 Ribosomal RNA adenine dimethylase 2.1E-05 73-134 / 14-73
PF04816.11 tRNA (adenine(22)-N(1))-methyltransferase 2.1E-05 93-134 / 1-42
PF03269.13 Caenorhabditis protein of unknown function, DUF268 2.3E-05 91-218 / 2-112
PF02636.16 Putative S-adenosyl-L-methionine-dependent methyltransferase 2.5E-05 90-216 / 18-132
PF04445.12 Putative SAM-dependent methyltransferase 2.7E-05 78-134 / 53-107
PF01135.18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 4.1E-05 88-134 / 70-117
PF05711.10 Macrocin-O-methyltransferase (TylF) 4.3E-05 88-125 / 99-141
PF01795.18 MraW methylase family 4.3E-05 88-134 / 19-66
PF11312.7 Putative SAM-dependent methyltransferase 4.4E-05 89-218 / 143-292
PF03059.15 Nicotianamine synthase protein 5E-05 89-216 / 121-231
PF07669.10 Eco57I restriction-modification methylase 7.3E-05 176-283 / 4-119
PF01189.16 16S rRNA methyltransferase RsmB/F 8.8E-05 89-134 / 8-54
PF03686.12 Uncharacterised protein family (UPF0146) 0.0001 89-124 / 14-49
PF05958.10 tRNA (Uracil-5-)-methyltransferase 0.0001 90-135 / 201-244
PF07757.12 Predicted AdoMet-dependent methyltransferase 0.0001 89-134 / 59-102
PF13649.5 Methyltransferase domain 0.00011 93-133 / 1-41
PF01728.18 FtsJ-like methyltransferase 0.00012 89-124 / 21-62
PF04989.11 Cephalosporin hydroxylase 0.00017 79-217 / 22-163
PF02005.15 N2,N2-dimethylguanosine tRNA methyltransferase 0.00017 89-219 / 100-210
PF08468.10 Methyltransferase small domain N-terminal 0.0002 89-217 / 12-105
PF05148.14 Hypothetical methyltransferase 0.00022 89-260 / 72-183
PF08704.9 tRNA methyltransferase complex GCD14 subunit 0.00024 86-134 / 37-86
PF06460.11 Coronavirus NSP13 0.00024 89-219 / 62-173
PF07279.10 Protein of unknown function (DUF1442) 0.0003 82-135 / 34-94
PF13651.5 Adenine-specific methyltransferase EcoRI 0.00044 67-110 / 9-55
PF09445.9 RNA cap guanine-N2 methyltransferase 0.00049 91-133 / 2-42
PF14314.5 Virus-capping methyltransferase 0.001 90-123 / 337-375
PF13578.5 Methyltransferase domain 0.0013 94-124 / 1-40
PF05575.10 Vibrio cholerae RfbT protein 0.0045 89-136 / 79-126
PF05206.13 Methyltransferase TRM13 0.0063 89-133 / 17-71
PF04072.13 Leucine carboxyl methyltransferase 0.0071 89-134 / 81-124

Annotations of the NCBI proteins of this PHROG


2:type I restriction-modification system, DNA-methyltransferase subunit M 1:hypothetical protein 1:methyltransferase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03427 hsdM : type I restriction enzyme M protein [EC:2.1.1.72] no pathways 264 8

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008990 rRNA (guanine-N2-)-methyltransferase activity
GO:0030410 nicotianamine synthase activity
GO:0008033 tRNA processing
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0003824 catalytic activity
GO:0008171 O-methyltransferase activity
GO:0003723 RNA binding
GO:0006480 N-terminal protein amino acid methylation
GO:0030418 nicotianamine biosynthetic process
GO:0008152 metabolic process
GO:0006304 DNA modification
GO:0008649 rRNA methyltransferase activity
GO:0070475 rRNA base methylation
GO:0009312 oligosaccharide biosynthetic process
GO:0031515 tRNA (m1A) methyltransferase complex
GO:0008610 lipid biosynthetic process
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0009452 7-methylguanosine RNA capping
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0006412 translation
GO:0006396 RNA processing
GO:0008168 methyltransferase activity
GO:0005737 cytoplasm
GO:0006306 DNA methylation
GO:0031167 rRNA methylation
GO:0008170 N-methyltransferase activity
GO:0016429 tRNA (adenine-N1-)-methyltransferase activity
GO:0001510 RNA methylation
GO:0003677 DNA binding
GO:0030488 tRNA methylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0009877 nodulation
GO:0032259 methylation

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