phrog_6397 is made of 19 protein sequences and is annotated as "ribonucleotide reductase large subunit"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
353.42 865 306


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY554769_p129 ARM66434.1 ribonucleotide diphosphate reductase alpha subunit KY554769 Lactococcus phage AM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554773_p130 ARM67165.1 ribonucleotide diphosphate reductase alpha subunit KY554773 Lactococcus phage AM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554774_p130 ARM67343.1 ribonucleotide diphosphate reductase alpha subunit KY554774 Lactococcus phage AM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023574_p140 YP_009007018.1 ribonucleotide diphosphate reductase alpha subunit NC_023574 Lactococcus phage phiL47 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554768_p130 ARM66257.1 ribonucleotide diphosphate reductase alpha subunit KY554768 Lactococcus phage AM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554775_p130 ARM67522.1 ribonucleotide diphosphate reductase alpha subunit KY554775 Lactococcus phage AM11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF001358_p48 ASZ76714.1 thioredoxin reductase MF001358 Enterococcus phage EF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023719_p336 YP_009015647.1 gp344 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF001361_p102 ASZ77477.1 thioredoxin reductase MF001361 Enterococcus phage EF5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554776_p130 ARQ95709.1 ribonucleotide diphosphate reductase alpha subunit KY554776 Lactococcus phage AM12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554777_p132 ARM67702.1 ribonucleotide diphosphate reductase alpha subunit KY554777 Lactococcus phage LW81 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554772_p136 ARM66989.1 ribonucleotide diphosphate reductase alpha subunit KY554772 Lactococcus phage AM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554770_p129 ARM66611.1 ribonucleotide diphosphate reductase alpha subunit KY554770 Lactococcus phage AM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_027341_p133 YP_009147790.1 ribonucleotide diphosphate reductas alpha subunit NC_027341 Lactococcus phage WRP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554771_p97 ARM66756.1 ribonucleotide diphosphate reductase alpha subunit KY554771 Lactococcus phage AM4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p39559 no NCBI prot ID no annotation VI_12210 Halobacteria_gi_448303253_72276_133184 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses; Haloviruses.
p329415 no NCBI prot ID no annotation VI_04046 unknown_gi_547178034 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p14771 no NCBI prot ID no annotation VI_04348 Alphaproteobacteria_gi_365882891 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MF172979_p84 ASD51141.1 putative dihydrolipoamide dehydrogenase MF172979 Erysipelothrix phage phi1605 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_9040 12 no annotation unknown function 12 0 1000
phrog_1815 83 guanylate kinase other 12 7.42E-45 35.25

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_33286 no annotation unknown function 93.3 0.011 4-55 / 9-64
phrog_9677 no annotation unknown function 92.8 0.015 4-43 / 1-41

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00743.18 Flavin-binding monooxygenase-like 1.2E-09 395-538 / 2-195
PF13434.5 L-lysine 6-monooxygenase (NADPH-requiring) 0.0012 244-279 / 178-217
PF13738.5 Pyridine nucleotide-disulphide oxidoreductase 0.0048 244-278 / 150-184
PF07992.13 Pyridine nucleotide-disulphide oxidoreductase 0.0019 247-367 / 139-234
PF01134.21 Glucose inhibited division protein A 5E-06 396-427 / 1-32
PF03486.13 HI0933-like protein 7.7E-05 395-428 / 1-34
PF01494.18 FAD binding domain 2E-07 395-427 / 2-34
PF05834.11 Lycopene cyclase protein 3.1E-06 396-427 / 1-32
PF04831.12 Popeye protein conserved region 1.2E-07 33-148 / 97-212
PF01946.16 Thi4 family 1.6E-06 391-428 / 14-53
PF13454.5 FAD-NAD(P)-binding 8.8E-06 398-426 / 1-33
PF13183.5 4Fe-4S dicluster domain 6.8E-07 639-715 / 2-76
PF00890.23 FAD binding domain 4.8E-05 396-427 / 1-32
PF12831.6 FAD dependent oxidoreductase 4.4E-05 396-428 / 1-33
PF13187.5 4Fe-4S dicluster domain 7E-07 695-712 / 55-72
PF04820.13 Tryptophan halogenase 6.9E-05 396-427 / 1-35
PF00027.28 Cyclic nucleotide-binding domain 1.1E-06 48-134 / 2-88
PF17179.3 4Fe-4S dicluster domain 1.9E-06 695-713 / 77-95
PF13484.5 4Fe-4S double cluster binding domain 6.9E-06 641-712 / 1-65
PF14697.5 4Fe-4S dicluster domain 8.8E-06 637-715 / 3-57
PF06100.10 MCRA family 0.001 395-428 / 2-39
PF13534.5 4Fe-4S dicluster domain 2.4E-05 641-713 / 1-55
PF13370.5 4Fe-4S single cluster domain of Ferredoxin I 2.7E-05 640-715 / 3-56
PF12838.6 4Fe-4S dicluster domain 2.8E-05 641-713 / 1-47
PF00996.17 GDP dissociation inhibitor 0.0023 393-429 / 3-39
PF00732.18 GMC oxidoreductase 0.0018 395-428 / 1-35
PF06902.10 Divergent 4Fe-4S mono-cluster 6E-05 635-717 / 8-62
PF01266.23 FAD dependent oxidoreductase 0.0019 396-426 / 1-31
PF13746.5 4Fe-4S dicluster domain 7.4E-05 635-718 / 54-104
PF13459.5 4Fe-4S single cluster domain 0.00011 637-715 / 3-59
PF06039.14 Malate:quinone oxidoreductase (Mqo) 0.0047 395-427 / 2-36
PF12798.6 4Fe-4S binding domain 0.00054 642-654 / 1-13
PF05187.12 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 0.00013 637-718 / 29-92
PF13237.5 4Fe-4S dicluster domain 0.0002 696-710 / 38-52
PF13247.5 4Fe-4S dicluster domain 0.00051 697-717 / 72-101
PF12800.6 4Fe-4S binding domain 0.00093 697-716 / 2-21
PF00070.26 Pyridine nucleotide-disulphide oxidoreductase 0.0085 396-428 / 1-33
PF12837.6 4Fe-4S binding domain 0.0036 637-655 / 4-22
PF10588.8 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 0.0023 601-622 / 1-29
PF12797.6 4Fe-4S binding domain 0.0026 636-653 / 4-21
PF13450.5 NAD(P)-binding Rossmann-like domain 0.0032 250-280 / 1-31
PF14691.5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 0.0032 636-656 / 18-40
PF00037.26 4Fe-4S binding domain 0.004 697-714 / 6-23

Annotations of the NCBI proteins of this PHROG


11:ribonucleotide diphosphate reductase alpha subunit 2:thioredoxin reductase 1:dihydrolipoamide dehydrogenase 1:ribonucleotide diphosphate reductas alpha subunit 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00384 trxB : thioredoxin reductase (NADPH) [EC:1.8.1.9] ko00240 Pyrimidine metabolism
ko00450 Selenocompound metabolism
338 15

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006631 fatty acid metabolic process
GO:0007264 small GTPase mediated signal transduction
GO:0050151 oleate hydratase activity
GO:0016020 membrane
GO:0050660 flavin adenine dinucleotide binding
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0055114 oxidation-reduction process
GO:0008033 tRNA processing
GO:0008924 malate dehydrogenase (quinone) activity
GO:0016491 oxidoreductase activity
GO:0071949 FAD binding
GO:0006099 tricarboxylic acid cycle
GO:0005092 GDP-dissociation inhibitor activity
GO:0050661 NADP binding
GO:0004499 N,N-dimethylaniline monooxygenase activity

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