phrog_6499 is made of 18 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
157.33 212 159


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p14253 no NCBI prot ID no annotation VI_01278 Clostridia_gi_548246196 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p32511 no NCBI prot ID no annotation VI_05770 Clostridia_gi_537985678_1655908_1720767 Viruses.
p354463 no NCBI prot ID no annotation VI_12318 Negativicutes_gi_553308188_0_19186 Viruses.
p60230 no NCBI prot ID no annotation VI_05811 Clostridia_gi_484165891 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p33938 no NCBI prot ID no annotation VI_01128 Clostridia_gi_545413440 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
MG711465_p5 AUV56624.1 helix-turn-helix domain-containing protein MG711465 Faecalibacterium phage FP_Brigit Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Brigitvirus; Faecalibacterium virus Brigit.
p358870 no NCBI prot ID no annotation VI_05925 Clostridia_gi_544988586 Viruses.
p384583 no NCBI prot ID no annotation VI_05826 Clostridia_gi_499152505 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p98490 no NCBI prot ID no annotation VI_01213 Clostridia_gi_546162569_1631445_1676706 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p16998 no NCBI prot ID no annotation VI_01301 Clostridia_gi_483984649 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p22745 no NCBI prot ID no annotation VI_01134 Clostridia_gi_545624061 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p275458 no NCBI prot ID no annotation VI_12314 Negativicutes_gi_520878374_0_29341 Viruses.
p27300 no NCBI prot ID no annotation VI_01252 Clostridia_gi_547850312 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KU517658_p9 AMB17421.1 transcriptional regulator KU517658 Clostridium phage HM T Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p180474 no NCBI prot ID no annotation VI_01248 Clostridia_gi_547833238 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p54393 no NCBI prot ID no annotation VI_01307 Clostridia_gi_485075759_38224_92961 Viruses.
p49471 no NCBI prot ID no annotation VI_01135 Clostridia_gi_545639314_6496_63820 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p62341 no NCBI prot ID no annotation VI_01138 Clostridia_gi_545644210_13585_64916 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3 3832 transcriptional repressor transcription regulation 10 3.12E-18 8.63
phrog_19458 4 primase DNA, RNA and nucleotide metabolism 2 2.15E-13 3.79
phrog_7338 16 no annotation unknown function 2 3.02E-11 1.64
phrog_13782 7 no annotation unknown function 2 1.89E-12 2.85

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_101 CII-like transcriptional activator transcription regulation 97.0 3.5E-06 26-137 / 24-138
phrog_1124 transcriptional regulator transcription regulation 96.7 1.6E-05 27-151 / 21-150
phrog_1373 transcriptional regulator transcription regulation 95.6 0.00046 10-67 / 35-86
phrog_14076 transcriptional regulator transcription regulation 90.7 0.049 10-65 / 5-56
phrog_147 transcriptional regulator transcription regulation 94.4 0.0034 13-75 / 9-65
phrog_1668 tail assembly protein tail 90.9 0.045 16-87 / 15-87
phrog_19114 no annotation unknown function 91.8 0.029 10-72 / 75-131
phrog_2104 no annotation unknown function 95.6 0.0005 11-67 / 50-100
phrog_2328 transcriptional repressor transcription regulation 95.9 0.00022 12-67 / 21-70
phrog_2439 transcriptional regulator transcription regulation 96.1 0.00012 8-147 / 8-139
phrog_25567 no annotation unknown function 93.5 0.0087 3-62 / 41-100
phrog_2967 transcriptional regulator transcription regulation 96.2 9.5E-05 10-75 / 12-74
phrog_3865 no annotation unknown function 90.9 0.044 16-46 / 21-45
phrog_3 transcriptional repressor transcription regulation 95.2 0.00095 11-65 / 8-55
phrog_4836 CII-like regulator transcription regulation 92.8 0.015 3-65 / 79-135
phrog_4 transcriptional repressor transcription regulation 91.5 0.033 28-67 / 17-54
phrog_5119 no annotation unknown function 90.8 0.047 11-66 / 58-107
phrog_5823 transcriptional regulator transcription regulation 94.6 0.0025 12-66 / 10-59
phrog_6962 no annotation unknown function 96.2 0.0001 27-58 / 16-47
phrog_7241 transcriptional regulator transcription regulation 91.8 0.029 12-68 / 67-117
phrog_8 transcriptional regulator transcription regulation 96.3 6.1E-05 11-67 / 6-54
phrog_9908 DNA binding protein DNA, RNA and nucleotide metabolism 91.5 0.034 8-75 / 16-79

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF06892.10 Phage regulatory protein CII (CP76) 3E-09 6-154 / 6-145
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.3E-07 5-67 / 7-75
PF13744.5 Helix-turn-helix domain 3.4E-06 7-67 / 17-78
PF14590.5 Domain of unknown function (DUF4447) 4.9E-06 4-67 / 3-69
PF05339.10 Protein of unknown function (DUF739) 5.1E-06 10-67 / 5-62
PF01381.21 Helix-turn-helix 6.1E-06 15-65 / 3-53
PF04645.11 Protein of unknown function, DUF603 1.2E-05 3-58 / 2-60
PF13413.5 Helix-turn-helix domain 1.3E-05 14-64 / 2-58
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 1.3E-05 13-68 / 3-58
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.2E-05 14-68 / 3-60
PF05269.10 Bacteriophage CII protein 2.3E-05 4-69 / 4-69
PF13560.5 Helix-turn-helix domain 2.4E-05 9-63 / 2-57
PF12844.6 Helix-turn-helix domain 2.4E-05 13-67 / 4-58
PF08667.9 BetR domain 5.4E-05 6-69 / 3-70
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 5.8E-05 9-67 / 70-127
PF08965.9 Domain of unknown function (DUF1870) 7.8E-05 10-63 / 3-58
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00011 16-66 / 4-53
PF14549.5 DNA-binding transcriptional regulator Cro 0.00049 14-66 / 3-51
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00064 9-60 / 114-165
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00067 6-61 / 5-64
PF13693.5 Winged helix-turn-helix DNA-binding 0.0007 12-68 / 6-59
PF12116.7 Stage III sporulation protein D 0.0008 20-63 / 18-62
PF00356.20 Bacterial regulatory proteins, lacI family 0.0023 23-53 / 1-31
PF10654.8 Protein of unknown function (DUF2481) 0.004 19-46 / 78-105
PF02376.14 CUT domain 0.0042 7-64 / 6-62

Annotations of the NCBI proteins of this PHROG


1:transcriptional regulator 1:helix-turn-helix domain-containing protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0006355 regulation of transcription, DNA-templated
GO:0005634 nucleus

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