phrog_6819 is made of 17 protein sequences and is annotated as "Holliday junction branch migration helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
653.94 1011 645


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_010155_p9 YP_001604351.1 putative helicase NC_010155 Acidianus filamentous virus 3 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
NC_010537_p10 YP_001798528.1 putative Holliday junction branch migration helicase NC_010537 Acidianus filamentous virus 9 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
NC_003214_p7 NP_445672.1 putative helicase NC_003214 Sulfolobus islandicus filamentous virus Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
KX467643_p6 AOS58361.1 lipothrixviral Holliday junction branch migration helicase KX467643 Sulfolobus islandicus filamentous virus 2 (SIFV2) Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus; Sulfolobus islandicus filamentous virus.
NC_010152_p9 YP_001604167.1 putative helicase NC_010152 Acidianus filamentous virus 6 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
NC_010154_p6 YP_001604287.1 putative helicase NC_010154 Acidianus filamentous virus 8 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
EU545650_p10 ACB37244.1 putative Holliday junction branch migration helicase EU545650 Acidianus filamentous virus 9 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
NC_010153_p4 YP_001604228.1 putative helicase NC_010153 Acidianus filamentous virus 7 Viruses; Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
p389569 no NCBI prot ID no annotation VI_12493 unknown_gi_484235599_6649_21987 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p389585 no NCBI prot ID no annotation VI_12496 unknown_gi_506495612_27125_42463 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p305110 no NCBI prot ID no annotation VI_12249 Halobacteria_gi_448543799_10614_35830 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p372308 no NCBI prot ID no annotation VI_03987 Halobacteria_gi_292654178_238920_256155 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p305407 no NCBI prot ID no annotation VI_12251 Halobacteria_gi_448558771_8784_33975 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p305408 no NCBI prot ID no annotation VI_12250 Halobacteria_gi_448550861_23992_49182 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p406757 no NCBI prot ID no annotation VI_12232 Halobacteria_gi_448383777_0_13354 Viruses.
p316937 no NCBI prot ID no annotation VI_12231 Halobacteria_gi_448376649_179780_203485 Viruses.
p420037 no NCBI prot ID no annotation VI_03177 Gammaproteobacteria_gi_553801190_451413_463264 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12842 8 no annotation unknown function 8 0 1000
phrog_1706 88 CRISPR/Cas system associated DNA, RNA and nucleotide metabolism 6 3.21E-23 13.61
phrog_19172 4 no annotation unknown function 4 0 1000
phrog_38159 2 no annotation unknown function 2 0 1000
phrog_10371 10 DNA helicase DNA, RNA and nucleotide metabolism 2 2.27E-12 2.77
phrog_35216 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10691 no annotation unknown function 95.1 0.0013 20-154 / 327-458
phrog_16259 DNA helicase DNA, RNA and nucleotide metabolism 97.8 3.2E-08 20-146 / 113-232
phrog_16694 no annotation unknown function 98.0 6.1E-09 8-345 / 258-663
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 96.1 0.00013 27-186 / 27-143
phrog_16 DNA helicase DNA, RNA and nucleotide metabolism 99.8 5E-25 20-345 / 2-305
phrog_170 PhoH-like phosphate starvation-inducible other 96.3 6.7E-05 18-174 / 30-192
phrog_197 Zot-like toxin moron, auxiliary metabolic gene and host takeover 93.7 0.0076 40-188 / 5-132
phrog_23807 no annotation unknown function 90.7 0.048 34-152 / 144-278
phrog_2467 no annotation unknown function 92.1 0.024 40-149 / 5-114
phrog_2488 DNA helicase DNA, RNA and nucleotide metabolism 99.0 3.2E-13 18-354 / 33-548
phrog_2666 terminase large subunit head and packaging 93.8 0.0069 136-175 / 116-155
phrog_26785 no annotation unknown function 93.8 0.0065 233-345 / 705-832
phrog_2765 PhoH-like phosphate starvation-inducible other 91.3 0.036 24-184 / 254-411
phrog_296 DNA transposition protein integration and excision 91.8 0.028 25-61 / 80-116
phrog_29996 no annotation unknown function 92.6 0.018 39-357 / 720-1119(1164)
phrog_30356 helicase DNA, RNA and nucleotide metabolism 90.0 0.064 28-175 / 10-138
phrog_31517 no annotation unknown function 99.6 6.8E-20 19-362 / 301-741
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 96.2 8.8E-05 17-185 / 2-149
phrog_33220 no annotation unknown function 96.8 1E-05 43-357 / 836-1169(1558)
phrog_34613 no annotation unknown function 97.0 3.6E-06 20-360 / 252-582
phrog_35989 no annotation unknown function 99.7 4.9E-22 21-355 / 147-531
phrog_3830 no annotation unknown function 95.1 0.0013 23-351 / 274-703
phrog_4913 replication DNA, RNA and nucleotide metabolism 94.0 0.0053 37-340 / 525-830
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 91.1 0.041 30-58 / 104-133
phrog_5173 no annotation unknown function 93.3 0.011 28-304 / 54-297
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 93.6 0.0078 134-208 / 95-162
phrog_62 DNA helicase DNA, RNA and nucleotide metabolism 99.4 3.4E-17 19-346 / 4-412
phrog_9690 DNA helicase DNA, RNA and nucleotide metabolism 95.0 0.0014 233-346 / 157-259
phrog_9 terminase large subunit head and packaging 93.7 0.0074 18-181 / 22-187

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF02889.15 Sec63 Brl domain 1.9E-16 673-886 / 1-206
PF06862.11 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 7E-16 467-585 / 358-467
PF02399.14 Origin of replication binding protein 8.8E-14 265-573 / 47-380
PF16203.4 ERCC3/RAD25/XPB C-terminal helicase 2.2E-08 467-593 / 60-180
PF14617.5 U3-containing 90S pre-ribosomal complex subunit 2E-07 238-377 / 51-203
PF00271.30 Helicase conserved C-terminal domain 2.7E-07 467-572 / 17-118
PF11496.7 Class II histone deacetylase complex subunits 2 and 3 5.8E-06 467-601 / 104-231
PF00270.28 DEAD/DEAH box helicase 1.1E-05 254-381 / 2-133
PF13872.5 P-loop containing NTP hydrolase pore-1 1.3E-05 251-381 / 35-189
PF07517.13 SecA DEAD-like domain 1.4E-05 250-380 / 89-224
PF13871.5 C-terminal domain on Strawberry notch homologue 4.1E-05 495-573 / 25-114
PF13086.5 AAA domain 0.00011 252-315 / 2-67
PF12340.7 Protein of unknown function (DUF3638) 0.00027 252-317 / 23-87
PF00176.22 SNF2 family N-terminal domain 0.00031 255-381 / 1-169
PF02562.15 PhoH-like protein 0.00044 249-308 / 2-62
PF07652.13 Flavivirus DEAD domain 0.0005 266-316 / 3-54
PF04408.22 Helicase associated domain (HA2) 0.00066 654-696 / 1-40
PF04851.14 Type III restriction enzyme, res subunit 0.0018 252-309 / 4-65
PF10391.8 Fingers domain of DNA polymerase lambda 0.0027 834-880 / 3-47
PF11731.7 Pathogenicity locus 0.0029 832-887 / 6-63
PF03118.14 Bacterial RNA polymerase, alpha chain C terminal domain 0.008 839-885 / 20-69

Annotations of the NCBI proteins of this PHROG


5:helicase 2:Holliday junction branch migration helicase 1:lipothrixviral Holliday junction branch migration helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03725 K03725 : archaea-specific helicase [EC:3.6.1.-] no pathways 1330 6

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0017038 protein import
GO:0016020 membrane
GO:0003676 nucleic acid binding
GO:0016575 histone deacetylation
GO:0070823 HDA1 complex
GO:0008026 ATP-dependent helicase activity
GO:0003677 DNA binding
GO:0006260 DNA replication
GO:0006351 transcription, DNA-templated
GO:0016787 hydrolase activity
GO:0003688 DNA replication origin binding
GO:0004386 helicase activity
GO:0034061 DNA polymerase activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity

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