phrog_6831 is made of 17 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
70.71 102 66


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p431926 no NCBI prot ID no annotation VI_12195 Gammaproteobacteria_gi_584594865 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p33500 no NCBI prot ID no annotation VI_02577 Gammaproteobacteria_gi_491285124 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
p275631 no NCBI prot ID no annotation VI_09652 Gammaproteobacteria_gi_458775987_356067_385385 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KT588075_p18 ALJ99113.1 XRE family transcriptional regulator KT588075 Acinetobacter phage Ab105-2phi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vieuvirus; unclassified Vieuvirus.
p315805 no NCBI prot ID no annotation VI_09123 Gammaproteobacteria_gi_445406158 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p72471 no NCBI prot ID no annotation VI_07517 Gammaproteobacteria_gi_452704131_0_49186 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vieuvirus; Acinetobacter virus B1251; Acinetobacter phage YMC/09/02/B1251.
p74069 no NCBI prot ID no annotation VI_02578 Gammaproteobacteria_gi_491286131_396353_445164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vieuvirus; Acinetobacter virus B1251; Acinetobacter phage YMC/09/02/B1251.
p229586 no NCBI prot ID no annotation VI_09171 Gammaproteobacteria_gi_452732688_17311_51164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p99385 no NCBI prot ID no annotation VI_01094 Betaproteobacteria_gi_347537839_960551_1005744 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p327574 no NCBI prot ID no annotation VI_10369 Gammaproteobacteria_gi_485840046 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p199886 no NCBI prot ID no annotation VI_03574 Gammaproteobacteria_gi_332159624_1584617_1621273 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
p296935 no NCBI prot ID no annotation VI_10908 Gammaproteobacteria_gi_487455807 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_011551_p2 YP_002308515.1 putative Cro-like protein NC_011551 Bacteriophage APSE-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
NC_000935_p2 NP_050963.1 putative Cro-like protein NC_000935 Hamiltonella virus APSE1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
p57003 no NCBI prot ID no annotation VI_03629 Gammaproteobacteria_gi_484083662 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p178346 no NCBI prot ID no annotation VI_09475 Gammaproteobacteria_gi_484003973 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_005357_p30 NP_958700.1 putative Cro-like protein NC_005357 Bordetella virus BPP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Rauchvirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_725 196 CII-like regulator transcription regulation 8 2.22E-29 19.78
phrog_256 467 DNA helicase DNA, RNA and nucleotide metabolism 5 2.33E-16 6.75

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1033 ParB-like partition protein DNA, RNA and nucleotide metabolism 93.6 0.0083 6-36 / 132-162
phrog_11138 no annotation unknown function 93.4 0.0099 3-35 / 95-127
phrog_11145 DNA binding protein DNA, RNA and nucleotide metabolism 92.8 0.016 17-59 / 3-43
phrog_11187 transcriptional regulator transcription regulation 91.3 0.037 1-51 / 1-54
phrog_1124 transcriptional regulator transcription regulation 96.4 4E-05 14-58 / 18-62
phrog_1157 transposase integration and excision 96.3 7.6E-05 2-47 / 5-48
phrog_12540 no annotation unknown function 94.4 0.0033 5-34 / 19-48
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 94.2 0.0046 6-38 / 149-181
phrog_13326 no annotation unknown function 92.1 0.024 17-51 / 19-51
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 96.4 4.6E-05 5-44 / 9-47
phrog_1373 transcriptional regulator transcription regulation 98.6 4.7E-11 10-54 / 39-81
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 97.7 9.3E-08 6-57 / 12-63
phrog_14131 DNA binding protein DNA, RNA and nucleotide metabolism 93.5 0.0086 15-60 / 124-173
phrog_1468 transcriptional repressor transcription regulation 97.5 2.2E-07 6-40 / 11-45
phrog_147 transcriptional regulator transcription regulation 95.2 0.0011 13-60 / 13-60
phrog_1529 no annotation unknown function 97.8 4.1E-08 4-58 / 4-59
phrog_1590 no annotation unknown function 95.9 0.0002 5-55 / 52-101
phrog_16553 transcriptional repressor transcription regulation 97.3 1.1E-06 3-63 / 10-67
phrog_1728 transcriptional regulator transcription regulation 94.8 0.002 5-55 / 6-54
phrog_1740 RNA polymerase sigma factor transcription regulation 92.1 0.024 5-37 / 132-164
phrog_17493 no annotation unknown function 97.4 4.7E-07 3-61 / 39-95
phrog_18104 transcriptional regulator transcription regulation 96.6 1.8E-05 1-58 / 1-54
phrog_18318 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.3 0.037 5-47 / 36-77
phrog_18376 no annotation unknown function 95.6 0.00044 3-58 / 79-134
phrog_19579 transcriptional regulator transcription regulation 91.4 0.035 12-40 / 12-40
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00034 10-37 / 65-92
phrog_2104 no annotation unknown function 92.3 0.022 8-57 / 50-97
phrog_2119 no annotation unknown function 95.4 0.00075 1-43 / 14-55
phrog_2159 ParB-like partition protein DNA, RNA and nucleotide metabolism 91.3 0.038 5-37 / 121-153
phrog_2328 transcriptional repressor transcription regulation 96.1 0.00012 7-45 / 20-56
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.1 4.4E-09 7-40 / 29-62
phrog_2439 transcriptional regulator transcription regulation 96.5 3.8E-05 9-56 / 13-58
phrog_25161 no annotation unknown function 91.0 0.043 1-40 / 1-40
phrog_2538 terminase small subunit head and packaging 95.6 0.00041 5-37 / 9-41
phrog_25952 no annotation unknown function 91.2 0.039 8-62 / 16-70
phrog_26693 no annotation unknown function 92.9 0.014 3-38 / 197-232
phrog_27475 no annotation unknown function 92.4 0.02 7-46 / 9-47
phrog_2967 transcriptional regulator transcription regulation 96.4 4.3E-05 8-56 / 14-61
phrog_296 DNA transposition protein integration and excision 95.5 0.00058 11-55 / 10-53
phrog_30447 no annotation unknown function 91.0 0.043 8-39 / 22-54
phrog_309 terminase small subunit head and packaging 94.7 0.0022 6-35 / 15-44
phrog_32138 DNA binding protein DNA, RNA and nucleotide metabolism 90.6 0.051 15-38 / 18-41
phrog_3282 sigma factor transcription regulation 90.8 0.046 12-33 / 29-50
phrog_34341 transcriptional regulator transcription regulation 92.8 0.015 7-39 / 75-108
phrog_34939 no annotation unknown function 95.4 0.00071 5-60 / 11-66
phrog_351 RNA polymerase sigma factor transcription regulation 95.6 0.00048 14-38 / 193-217
phrog_357 transcriptional repressor transcription regulation 95.4 0.00072 5-37 / 14-46
phrog_35 transcriptional repressor transcription regulation 95.3 0.00086 8-53 / 5-49
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.3 0.00088 15-53 / 20-56
phrog_38027 transcriptional repressor transcription regulation 96.4 4.9E-05 12-54 / 67-107
phrog_3803 RIIB lysis inhibitor lysis 93.8 0.0065 1-44 / 1-44
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00046 6-34 / 70-98
phrog_3910 transcriptional regulator transcription regulation 91.8 0.029 3-36 / 64-100
phrog_3951 no annotation unknown function 93.8 0.0065 6-40 / 245-279
phrog_3 transcriptional repressor transcription regulation 97.5 2.2E-07 9-54 / 10-52
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 95.4 0.00077 5-37 / 10-42
phrog_4268 transcriptional repressor transcription regulation 94.3 0.0037 12-54 / 45-83
phrog_4291 RNA-dependent RNA polymerase DNA, RNA and nucleotide metabolism 93.8 0.007 6-38 / 874-906
phrog_4583 transcriptional repressor transcription regulation 96.4 4E-05 7-40 / 15-48
phrog_4646 transposase integration and excision 93.4 0.0094 5-38 / 12-46
phrog_4779 transcriptional regulator transcription regulation 96.8 1.2E-05 6-40 / 5-39
phrog_4 transcriptional repressor transcription regulation 96.0 0.00015 13-54 / 12-49
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.6 2.6E-05 8-39 / 72-103
phrog_5229 no annotation unknown function 93.9 0.0059 9-36 / 75-102
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.016 15-57 / 20-60
phrog_5536 no annotation unknown function 96.2 9.8E-05 6-50 / 12-53
phrog_5767 sigma factor transcription regulation 94.0 0.0056 4-37 / 295-328
phrog_57 terminase small subunit head and packaging 93.7 0.0072 15-63 / 2-58
phrog_5823 transcriptional regulator transcription regulation 96.5 3.8E-05 13-57 / 15-58
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 92.4 0.02 15-40 / 111-136
phrog_609 RIIB lysis inhibitor lysis 92.4 0.02 8-40 / 15-48
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 96.7 1.2E-05 8-40 / 27-59
phrog_6223 transcriptional repressor transcription regulation 99.2 2.8E-15 3-64 / 6-65
phrog_6288 no annotation unknown function 93.8 0.0067 10-53 / 19-62
phrog_638 transcriptional regulator transcription regulation 94.1 0.0048 4-52 / 3-51
phrog_6463 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.4 0.036 13-57 / 31-81
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.0051 6-40 / 10-44
phrog_66 excisionase and transcriptional regulator integration and excision 90.6 0.05 15-38 / 9-32
phrog_704 DNA repair exonuclease DNA, RNA and nucleotide metabolism 91.4 0.034 2-32 / 3-34
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0025 8-37 / 37-66
phrog_7067 terminase small subunit head and packaging 91.2 0.039 6-34 / 22-50
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00014 6-51 / 21-64
phrog_7168 homing endonuclease DNA, RNA and nucleotide metabolism 92.7 0.017 5-38 / 229-261
phrog_7241 transcriptional regulator transcription regulation 97.3 7.1E-07 13-56 / 72-113
phrog_725 CII-like regulator transcription regulation 94.6 0.0027 15-63 / 27-71
phrog_7344 terminase small subunit head and packaging 90.6 0.05 9-37 / 20-48
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 8-35 / 10-38
phrog_769 transcriptional repressor transcription regulation 95.2 0.001 3-40 / 13-50
phrog_7950 transcriptional repressor transcription regulation 94.4 0.0035 13-38 / 20-45
phrog_8038 no annotation unknown function 99.0 2.2E-13 2-60 / 1-58
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 7.3E-05 12-58 / 14-59
phrog_8 transcriptional regulator transcription regulation 97.0 3.4E-06 6-56 / 4-51
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.4 0.035 8-43 / 10-44
phrog_9366 transposase integration and excision 95.0 0.0014 1-36 / 67-102
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 93.6 0.0081 16-36 / 19-39

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04936.11 Protein of unknown function (DUF658) 5.7E-06 32-96 / 14-109
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.1E-05 18-56 / 9-47
PF01381.21 Helix-turn-helix 0.00015 29-56 / 6-33
PF10654.8 Protein of unknown function (DUF2481) 0.00026 29-56 / 77-104
PF04645.11 Protein of unknown function, DUF603 0.00038 19-57 / 7-48
PF05339.10 Protein of unknown function (DUF739) 0.0004 25-56 / 9-40
PF13413.5 Helix-turn-helix domain 0.0006 29-56 / 6-33
PF14590.5 Domain of unknown function (DUF4447) 0.00083 20-56 / 8-44
PF06322.10 Phage NinH protein 0.0013 26-57 / 10-41
PF01710.15 Transposase 0.0013 30-95 / 16-90
PF13744.5 Helix-turn-helix domain 0.0014 24-56 / 23-55
PF08965.9 Domain of unknown function (DUF1870) 0.0014 24-56 / 6-40
PF00292.17 'Paired box' domain 0.0015 30-56 / 31-57
PF12116.7 Stage III sporulation protein D 0.0018 31-56 / 18-43
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.002 30-55 / 8-34
PF00356.20 Bacterial regulatory proteins, lacI family 0.0024 34-56 / 1-23
PF13011.5 leucine-zipper of insertion element IS481 0.0029 27-57 / 19-49
PF08535.9 KorB domain 0.0029 31-56 / 2-27
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0096 74-95 / 12-33
PF07750.10 GcrA cell cycle regulator 0.0068 29-56 / 15-43
PF12844.6 Helix-turn-helix domain 0.0033 30-56 / 10-36
PF10975.7 Protein of unknown function (DUF2802) 0.0033 65-95 / 33-63
PF05269.10 Bacteriophage CII protein 0.0036 29-55 / 20-46
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.004 31-56 / 10-36
PF07141.10 Putative bacteriophage terminase small subunit 0.0039 30-57 / 29-56
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0046 26-56 / 120-150
PF05344.10 Domain of Unknown Function (DUF746) 0.0049 30-56 / 10-36
PF13560.5 Helix-turn-helix domain 0.0055 27-56 / 9-38
PF10668.8 Phage terminase small subunit 0.0056 32-56 / 22-46
PF02954.18 Bacterial regulatory protein, Fis family 0.0062 31-54 / 15-38
PF04552.12 Sigma-54, DNA binding domain 0.0061 30-56 / 46-72
PF00376.22 MerR family regulatory protein 0.0071 35-56 / 2-23
PF08822.10 Protein of unknown function (DUF1804) 0.0079 30-56 / 17-43
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0079 29-56 / 79-106
PF07900.10 Protein of unknown function (DUF1670) 0.0081 30-94 / 93-171
PF02042.14 RWP-RK domain 0.0084 30-56 / 10-36
PF17443.1 Uncharacterized protein pXO2-72 0.0086 32-56 / 8-32
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0093 34-56 / 10-31
PF07453.12 NUMOD1 domain 0.0094 33-52 / 20-39

Annotations of the NCBI proteins of this PHROG


3:Cro-like protein 1:XRE family transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding

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