phrog_7126 is made of 17 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
120.88 135 119


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031107_p106 YP_009290736.1 putative transcriptional regulator NC_031107 Erwinia phage vB_EamM_Asesino Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Erskinevirus.
NC_027402_p101 YP_009153395.1 putative transcriptional regulator NC_027402 Salmonella phage SPN3US Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Seoulvirus.
NC_019929_p26 YP_007237676.1 putative transcriptional regulator NC_019929 Erwinia phage phiEaH2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Erskinevirus.
KX397373_p109 ANZ50546.1 putative transcriptional regulator KX397373 Erwinia phage vB_EamM_Stratton Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Erskinevirus; unclassified Erskinevirus.
KU726251_p102 AMR59753.1 putative transcriptional regulator KU726251 Enterobacteria phage SEGD1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Seoulvirus; Salmonella virus SPN3US.
NC_031010_p114 YP_009278727.1 hypothetical protein NC_031010 Erwinia phage vB_EamM_Kwan Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF459646_p180 ASU03490.1 helix turn helix XRE family domain protein MF459646 Erwinia phage vB_EamM_RisingSun Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Risingsunvirus; Erwinia virus Risingsun.
MF459647_p181 ASU03734.1 helix turn helix XRE family domain protein MF459647 Erwinia phage vB_EamM_Joad Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Risingsunvirus; unclassified Risingsunvirus.
AP017972_p78 BAW98287.1 hypothetical protein AP017972 Vibrio phage pTD1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tidunavirus; Vibrio virus pTD1.
MG720308_p120 AUR81071.1 hypothetical protein MG720308 Vibrio phage Aphrodite1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Aphroditevirus; Vibrio virus Aphrodite1.
KC131130_p131 AGB07245.1 hypothetical protein KC131130 Vibrio phage VP4B Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tidunavirus; Vibrio virus VP4B.
NC_031120_p105 YP_009292185.1 putative transcriptional regulator NC_031120 Erwinia phage vB_EamM_Caitlin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Machinavirus; unclassified Machinavirus.
KX397370_p105 ANZ49752.1 putative transcriptional regulator KX397370 Erwinia phage vB_EamM_Machina Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Machinavirus; Erwinia virus Machina.
NC_031126_p106 YP_009292806.1 putative transcriptional regulator NC_031126 Erwinia phage vB_EamM_ChrisDB Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Machinavirus; unclassified Machinavirus.
NC_031127_p105 YP_009293082.1 putative transcriptional regulator NC_031127 Erwinia phage vB_EamM_Huxley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Machinavirus; unclassified Machinavirus.
KX397371_p105 ANZ50024.1 putative transcriptional regulator KX397371 Erwinia phage vB_EamM_Parshik Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Machinavirus; unclassified Machinavirus.
NC_023610_p38 YP_009010091.1 hypothetical protein NC_023610 Erwinia phage PhiEaH1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Iapetusvirus; Erwinia virus EaH1.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8344 13 no annotation unknown function 9 3.90E-43 33.53
phrog_761 187 thymidylate kinase other 8 3.10E-26 16.63
phrog_22578 3 no annotation unknown function 3 0 1000
phrog_34769 2 no annotation unknown function 2 0 1000
phrog_31310 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11145 DNA binding protein DNA, RNA and nucleotide metabolism 94.8 0.0019 30-76 / 2-48
phrog_1124 transcriptional regulator transcription regulation 95.8 0.00031 14-91 / 2-83
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 92.8 0.015 26-70 / 15-61
phrog_1373 transcriptional regulator transcription regulation 97.6 1E-07 25-77 / 40-91
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 95.4 0.00071 17-72 / 8-65
phrog_1468 transcriptional repressor transcription regulation 95.4 0.00074 24-75 / 14-64
phrog_147 transcriptional regulator transcription regulation 94.0 0.0052 27-66 / 13-51
phrog_1529 no annotation unknown function 92.3 0.021 23-54 / 8-40
phrog_1728 transcriptional regulator transcription regulation 91.9 0.027 23-70 / 9-56
phrog_1746 transcriptional repressor transcription regulation 91.4 0.036 17-99 / 13-86
phrog_18318 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.9 5.5E-06 12-77 / 27-94
phrog_2119 no annotation unknown function 91.0 0.042 19-62 / 14-60
phrog_2136 no annotation unknown function 93.7 0.0077 31-70 / 43-82
phrog_2328 transcriptional repressor transcription regulation 95.1 0.0011 24-78 / 23-76
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 98.0 1.1E-08 11-85 / 17-93
phrog_23446 no annotation unknown function 93.4 0.0095 19-62 / 1-46
phrog_2439 transcriptional regulator transcription regulation 92.2 0.023 23-80 / 13-69
phrog_2538 terminase small subunit head and packaging 95.5 0.00053 24-64 / 13-54
phrog_2967 transcriptional regulator transcription regulation 94.9 0.0016 15-81 / 9-73
phrog_296 DNA transposition protein integration and excision 91.7 0.03 29-55 / 14-40
phrog_34939 no annotation unknown function 92.5 0.019 29-74 / 22-67
phrog_351 RNA polymerase sigma factor transcription regulation 92.1 0.024 28-53 / 193-218
phrog_35 transcriptional repressor transcription regulation 94.3 0.0037 28-66 / 12-49
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.5 0.019 28-54 / 19-45
phrog_3949 transcriptional repressor transcription regulation 94.0 0.0053 11-78 / 12-75
phrog_3 transcriptional repressor transcription regulation 97.2 1.6E-06 27-73 / 14-59
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.4 0.01 29-73 / 18-61
phrog_4583 transcriptional repressor transcription regulation 95.0 0.0014 29-72 / 23-65
phrog_4779 transcriptional regulator transcription regulation 95.0 0.0014 29-55 / 14-40
phrog_4 transcriptional repressor transcription regulation 94.3 0.0038 29-74 / 14-56
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.011 29-55 / 79-105
phrog_5823 transcriptional regulator transcription regulation 96.5 2.7E-05 28-89 / 16-73
phrog_59 HNH endonuclease DNA, RNA and nucleotide metabolism 91.8 0.029 29-54 / 111-136
phrog_6223 transcriptional repressor transcription regulation 97.1 2.5E-06 26-70 / 14-57
phrog_6288 no annotation unknown function 91.1 0.04 27-64 / 22-60
phrog_638 transcriptional regulator transcription regulation 95.8 0.00032 22-76 / 6-62
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 90.2 0.06 18-49 / 57-88
phrog_6831 transcriptional regulator transcription regulation 96.1 0.00013 21-71 / 6-57
phrog_7241 transcriptional regulator transcription regulation 96.4 4.7E-05 25-72 / 70-116
phrog_725 CII-like regulator transcription regulation 97.0 4.5E-06 21-72 / 19-66
phrog_769 transcriptional repressor transcription regulation 93.9 0.0059 21-80 / 16-72
phrog_8038 no annotation unknown function 95.4 0.00075 22-66 / 6-51
phrog_8522 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.4 0.035 25-82 / 15-70
phrog_8994 no annotation unknown function 93.3 0.01 28-77 / 17-66
phrog_8 transcriptional regulator transcription regulation 96.5 3.5E-05 28-73 / 13-55
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 95.7 0.00037 29-47 / 18-36

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 1.3E-09 13-80 / 7-77
PF13744.5 Helix-turn-helix domain 2.3E-09 12-79 / 14-79
PF14590.5 Domain of unknown function (DUF4447) 7.2E-09 15-82 / 6-73
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 1.2E-08 21-82 / 3-61
PF05339.10 Protein of unknown function (DUF739) 2.1E-08 19-79 / 6-63
PF01381.21 Helix-turn-helix 2.6E-08 24-77 / 4-54
PF04645.11 Protein of unknown function, DUF603 2.8E-08 13-80 / 4-68
PF13443.5 Cro/C1-type HTH DNA-binding domain 3.2E-08 23-80 / 4-61
PF12844.6 Helix-turn-helix domain 4.4E-08 22-81 / 5-61
PF13413.5 Helix-turn-helix domain 4.4E-08 24-76 / 4-59
PF08667.9 BetR domain 1.8E-07 16-82 / 5-72
PF13560.5 Helix-turn-helix domain 1.8E-07 18-78 / 3-63
PF05269.10 Bacteriophage CII protein 1.9E-07 22-81 / 16-70
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 2.1E-07 17-79 / 70-128
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 3.2E-07 33-81 / 10-57
PF08965.9 Domain of unknown function (DUF1870) 1E-06 18-80 / 3-67
PF14549.5 DNA-binding transcriptional regulator Cro 6.6E-06 23-78 / 4-52
PF13693.5 Winged helix-turn-helix DNA-binding 6.9E-06 20-81 / 6-61
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 1.1E-05 18-71 / 115-165
PF12116.7 Stage III sporulation protein D 1.3E-05 31-74 / 19-62
PF00157.16 Pou domain - N-terminal to homeobox domain 2.5E-05 15-72 / 6-64
PF02376.14 CUT domain 2.6E-05 16-81 / 7-68
PF00356.20 Bacterial regulatory proteins, lacI family 4.4E-05 33-67 / 1-34
PF10654.8 Protein of unknown function (DUF2481) 5.8E-05 31-56 / 80-105
PF08535.9 KorB domain 0.0011 31-56 / 3-28
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0023 31-55 / 13-37
PF04552.12 Sigma-54, DNA binding domain 0.0031 31-55 / 48-72
PF02042.14 RWP-RK domain 0.0036 31-55 / 12-36
PF07141.10 Putative bacteriophage terminase small subunit 0.0036 31-54 / 31-54
PF00376.22 MerR family regulatory protein 0.0038 34-55 / 2-23
PF01371.18 Trp repressor protein 0.0038 31-67 / 48-83
PF07506.10 RepB plasmid partitioning protein 0.0046 20-55 / 13-45
PF06322.10 Phage NinH protein 0.0052 31-55 / 16-40
PF06806.11 Putative excisionase (DUF1233) 0.0056 31-54 / 9-32
PF07278.10 Protein of unknown function (DUF1441) 0.0059 31-55 / 1-25

Annotations of the NCBI proteins of this PHROG


10:transcriptional regulator 4:hypothetical protein 2:helix turn helix XRE family domain protein 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0003700 DNA binding transcription factor activity
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0045892 negative regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly

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