phrog_7168 is made of 16 protein sequences and is annotated as "homing endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
254.69 417 282


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF001361_p151 ASZ77526.1 hypothetical protein MF001361 Enterococcus phage EF5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF001358_p170 ASZ76836.1 hypothetical protein MF001358 Enterococcus phage EF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554774_p98 ARM67311.1 hypothetical protein KY554774 Lactococcus phage AM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554768_p98 ARM66225.1 hypothetical protein KY554768 Lactococcus phage AM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554773_p97 ARM67132.1 hypothetical protein KY554773 Lactococcus phage AM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554776_p98 ARQ95677.1 hypothetical protein KY554776 Lactococcus phage AM12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554775_p97 ARM67489.1 hypothetical protein KY554775 Lactococcus phage AM11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554770_p97 ARM66579.1 hypothetical protein KY554770 Lactococcus phage AM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554769_p97 ARM66402.1 hypothetical protein KY554769 Lactococcus phage AM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX156762_p67 ANM47040.1 hypothetical protein KX156762 Staphylococcus phage vB_SauS_IMEP5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023719_p347 YP_009015658.1 gp355 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_029067_p30 YP_009222879.1 hypothetical protein NC_029067 Vibrio phage eugene 12A10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_021067_p262 YP_007877424.1 hypothetical protein NC_021067 Vibrio phage helene 12B3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF001361_p160 ASZ77535.1 hypothetical protein MF001361 Enterococcus phage EF5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF001358_p161 ASZ76827.1 hypothetical protein MF001358 Enterococcus phage EF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023719_p297 YP_009015608.1 gp305 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12023 8 DNA topoisomerase DNA, RNA and nucleotide metabolism 7 7.39E-37 27.25
phrog_543 253 DNA topoisomerase II large subunit DNA, RNA and nucleotide metabolism 7 2.74E-22 12.68
phrog_21661 4 no annotation unknown function 2 1.48E-13 3.95
phrog_21652 4 DNA polymerase DNA, RNA and nucleotide metabolism 2 1.48E-13 3.95
phrog_33561 2 no annotation unknown function 2 0 1000
phrog_20695 4 DNA binding protein DNA, RNA and nucleotide metabolism 2 1.48E-13 3.95

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1303 DNA binding protein DNA, RNA and nucleotide metabolism 92.0 0.025 117-217 / 27-124
phrog_19446 homing endonuclease DNA, RNA and nucleotide metabolism 99.2 3.2E-15 1-109 / 1-101
phrog_20015 endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0024 3-33 / 4-35
phrog_26160 no annotation unknown function 90.1 0.061 2-80 / 183-266
phrog_314 homing endonuclease DNA, RNA and nucleotide metabolism 99.7 1.6E-22 1-107 / 2-97
phrog_447 NAD synthetase other 97.8 4.2E-08 2-99 / 30-139
phrog_5123 homing endonuclease with GIY-YIG motif DNA, RNA and nucleotide metabolism 99.4 3.1E-17 1-108 / 1-103
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 92.1 0.024 195-261 / 18-91
phrog_6831 transcriptional regulator transcription regulation 91.5 0.034 229-261 / 5-38
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.059 195-267 / 16-93

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01541.23 GIY-YIG catalytic domain 7.4E-13 6-96 / 2-86
PF08822.10 Protein of unknown function (DUF1804) 0.00011 246-327 / 18-105
PF00292.17 'Paired box' domain 0.00015 245-324 / 31-125
PF01710.15 Transposase 0.0008 196-274 / 19-97
PF04936.11 Protein of unknown function (DUF658) 0.0001 196-275 / 15-116
PF07750.10 GcrA cell cycle regulator 0.00079 288-327 / 4-44
PF12759.6 InsA C-terminal domain 0.0051 296-325 / 15-44
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 7.7E-05 129-166 / 3-41
PF09607.9 Brinker DNA-binding domain 9.2E-05 122-163 / 4-50
PF07141.10 Putative bacteriophage terminase small subunit 0.0084 292-327 / 21-56
PF10654.8 Protein of unknown function (DUF2481) 0.00014 123-162 / 64-104
PF13011.5 leucine-zipper of insertion element IS481 0.00015 122-166 / 6-52
PF10668.8 Phage terminase small subunit 0.00052 123-165 / 4-49
PF02796.14 Helix-turn-helix domain of resolvase 0.00065 127-161 / 9-44
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0007 123-162 / 11-50
PF05344.10 Domain of Unknown Function (DUF746) 0.0008 134-165 / 8-39
PF13936.5 Helix-turn-helix domain 0.00086 124-160 / 5-42
PF11427.7 Tc3 transposase 0.00086 124-163 / 5-45
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.00081 122-162 / 87-131
PF04552.12 Sigma-54, DNA binding domain 0.0043 245-327 / 46-150
PF06627.10 Protein of unknown function (DUF1153) 0.00096 122-166 / 28-74
PF06322.10 Phage NinH protein 0.001 136-164 / 14-42
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.001 124-162 / 40-79
PF04218.12 CENP-B N-terminal DNA-binding domain 0.0013 124-162 / 7-47
PF13309.5 HTH domain 0.0013 124-159 / 20-62
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.0014 125-162 / 4-43
PF05331.10 Protein of unknown function (DUF742) 0.0013 122-165 / 37-80
PF15978.4 Tn7-like transposition protein D 0.0015 123-166 / 186-231
PF16677.4 DNA-packaging protein gp3 0.0016 124-162 / 6-53
PF01527.19 Transposase 0.0017 123-163 / 4-46
PF13518.5 Helix-turn-helix domain 0.0019 131-166 / 4-39
PF13411.5 MerR HTH family regulatory protein 0.0076 140-163 / 2-25
PF14493.5 Helix-turn-helix domain 0.0024 134-165 / 8-39
PF05225.15 helix-turn-helix, Psq domain 0.0029 135-162 / 13-41
PF02954.18 Bacterial regulatory protein, Fis family 0.0031 136-161 / 14-39
PF07638.10 ECF sigma factor 0.0032 124-162 / 134-173
PF08765.10 Mor transcription activator family 0.0032 137-163 / 71-97
PF17443.1 Uncharacterized protein pXO2-72 0.0039 137-162 / 7-32
PF08535.9 KorB domain 0.0041 137-165 / 2-30
PF13384.5 Homeodomain-like domain 0.0042 128-162 / 6-41
PF10975.7 Protein of unknown function (DUF2802) 0.0045 126-159 / 30-64
PF01371.18 Trp repressor protein 0.0048 129-163 / 38-73
PF07453.12 NUMOD1 domain 0.0049 138-158 / 19-39
PF13412.5 Winged helix-turn-helix DNA-binding 0.0056 137-164 / 16-43
PF01381.21 Helix-turn-helix 0.0065 136-161 / 7-32
PF06413.10 Neugrin 0.006 122-161 / 9-52
PF07506.10 RepB plasmid partitioning protein 0.0066 123-162 / 4-45
PF04545.15 Sigma-70, region 4 0.0071 136-161 / 22-47
PF07900.10 Protein of unknown function (DUF1670) 0.007 136-218 / 93-175
PF00376.22 MerR family regulatory protein 0.0075 140-162 / 1-23
PF08281.11 Sigma-70, region 4 0.0079 134-161 / 22-49
PF13551.5 Winged helix-turn helix 0.008 134-166 / 7-39
PF13404.5 AsnC-type helix-turn-helix domain 0.0086 136-161 / 15-40
PF00356.20 Bacterial regulatory proteins, lacI family 0.0087 140-162 / 1-23
PF16509.4 TrfB plasmid transcriptional repressor 0.0092 126-163 / 18-56
PF06806.11 Putative excisionase (DUF1233) 0.0092 137-160 / 8-31

Annotations of the NCBI proteins of this PHROG


16:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0005524 ATP binding
GO:0003700 DNA binding transcription factor activity
GO:0019069 viral capsid assembly
GO:0016987 sigma factor activity
GO:0006355 regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006352 DNA-templated transcription, initiation

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