phrog_7241 is made of 16 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
123.25 188 122


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p63620 no NCBI prot ID no annotation VI_05511 Betaproteobacteria_gi_149146613_0_50926 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p191093 no NCBI prot ID no annotation VI_05506 Betaproteobacteria_gi_149127571_0_37136 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p340781 no NCBI prot ID no annotation VI_04268 Alphaproteobacteria_gi_444310867 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p83713 no NCBI prot ID no annotation VI_05550 Betaproteobacteria_gi_485035271_0_47405 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
NC_003309_p69 NP_536425.1 putative helix-turn-helix transcriptional regulator NC_003309 Burkholderia virus phiE125 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
NC_009235_p69 YP_001111148.1 gp69 NC_009235 Burkholderia virus phi6442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
NC_005284_p81 NP_945111.1 gp80 NC_005284 Burkholderia virus phi1026b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Stanholtvirus.
p242671 no NCBI prot ID no annotation VI_04220 Alphaproteobacteria_gi_402850157 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p112924 no NCBI prot ID no annotation VI_02615 Gammaproteobacteria_gi_329124276_813_45072 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p276617 no NCBI prot ID no annotation VI_07364 Gammaproteobacteria_gi_417846251 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KP966108_p1 AKA61173.1 putative DNA-binding protein KP966108 Burkholderia phage vB_BceM_AP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Kisquinquevirus; Burkholderia virus AP3.
p287617 no NCBI prot ID no annotation VI_06418 Gammaproteobacteria_gi_145631693 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p69750 no NCBI prot ID no annotation VI_03532 Gammaproteobacteria_gi_407021225_2278261_2328024 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p286223 no NCBI prot ID no annotation VI_06367 Gammaproteobacteria_gi_193071368 Viruses.
p324749 no NCBI prot ID no annotation VI_01757 Gammaproteobacteria_gi_545286282 Viruses.
p265114 no NCBI prot ID no annotation VI_04166 Actinobacteria_gi_564018020 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1213 124 RelE-like toxin moron, auxiliary metabolic gene and host takeover 15 1.25E-58 49.03

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1124 transcriptional regulator transcription regulation 94.9 0.0017 69-116 / 14-63
phrog_11553 no annotation unknown function 91.1 0.04 66-116 / 40-89
phrog_13326 no annotation unknown function 96.0 0.00016 76-121 / 19-64
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 93.6 0.0079 64-114 / 9-61
phrog_1373 transcriptional regulator transcription regulation 99.1 4.2E-14 67-120 / 37-90
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 96.8 9.8E-06 69-118 / 18-67
phrog_14076 transcriptional regulator transcription regulation 92.1 0.024 66-118 / 6-62
phrog_14639 cro-like repressor transcription regulation 90.2 0.059 63-121 / 8-69
phrog_1468 transcriptional repressor transcription regulation 98.2 1.1E-09 66-119 / 12-64
phrog_147 transcriptional regulator transcription regulation 94.8 0.002 64-110 / 5-51
phrog_16278 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.5 0.00059 72-117 / 11-56
phrog_1702 transcriptional repressor transcription regulation 94.4 0.0035 67-122 / 20-77
phrog_1740 RNA polymerase sigma factor transcription regulation 90.0 0.065 67-98 / 135-166
phrog_1746 transcriptional repressor transcription regulation 93.9 0.0061 73-121 / 21-69
phrog_18104 transcriptional regulator transcription regulation 92.5 0.018 77-114 / 16-53
phrog_18815 no annotation unknown function 92.9 0.015 71-119 / 11-57
phrog_19579 transcriptional regulator transcription regulation 91.9 0.028 71-119 / 12-60
phrog_20342 no annotation unknown function 93.7 0.0072 1-72 / 2-74
phrog_2104 no annotation unknown function 97.4 5.9E-07 64-116 / 48-100
phrog_2119 no annotation unknown function 90.4 0.054 73-101 / 26-54
phrog_21847 no annotation unknown function 93.2 0.012 76-104 / 25-53
phrog_2268 antitoxin from a toxin-antitoxin system moron, auxiliary metabolic gene and host takeover 94.9 0.0018 5-46 / 26-67
phrog_2328 transcriptional repressor transcription regulation 98.1 2.7E-09 66-121 / 20-75
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 97.9 1.6E-08 64-117 / 27-81
phrog_2439 transcriptional regulator transcription regulation 98.3 8.1E-10 67-119 / 12-64
phrog_2838 transcriptional repressor transcription regulation 93.6 0.0079 65-119 / 33-104
phrog_29047 no annotation unknown function 93.6 0.0082 70-117 / 100-147
phrog_2967 transcriptional regulator transcription regulation 98.1 4.9E-09 66-121 / 13-69
phrog_296 DNA transposition protein integration and excision 93.1 0.013 66-112 / 6-53
phrog_32768 no annotation unknown function 93.8 0.0068 66-121 / 14-70
phrog_351 RNA polymerase sigma factor transcription regulation 94.5 0.0029 68-114 / 184-227
phrog_3557 transcriptional regulator transcription regulation 91.3 0.037 74-122 / 25-73
phrog_35 transcriptional repressor transcription regulation 96.8 1E-05 75-120 / 14-61
phrog_37057 transcriptional regulator transcription regulation 93.2 0.012 70-117 / 6-52
phrog_38027 transcriptional repressor transcription regulation 95.9 0.00022 59-120 / 54-116
phrog_3949 transcriptional repressor transcription regulation 95.1 0.0012 76-121 / 30-74
phrog_3951 no annotation unknown function 90.3 0.058 67-111 / 247-291
phrog_3 transcriptional repressor transcription regulation 98.4 1.7E-10 64-121 / 6-63
phrog_4031 no annotation unknown function 95.6 0.00044 66-118 / 520-573
phrog_409 transcriptional regulator transcription regulation 93.8 0.0069 69-98 / 6-34
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 92.9 0.015 73-98 / 19-44
phrog_4268 transcriptional repressor transcription regulation 94.4 0.0035 67-117 / 41-89
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.5 0.003 76-121 / 20-65
phrog_4583 transcriptional repressor transcription regulation 97.4 6E-07 65-121 / 14-70
phrog_4779 transcriptional regulator transcription regulation 95.7 0.00035 64-106 / 4-45
phrog_4836 CII-like regulator transcription regulation 95.9 0.00022 64-121 / 85-142
phrog_4 transcriptional repressor transcription regulation 97.9 2.3E-08 72-121 / 12-59
phrog_57 terminase small subunit head and packaging 90.4 0.054 74-98 / 2-26
phrog_5823 transcriptional regulator transcription regulation 98.2 1.1E-09 67-121 / 10-65
phrog_6223 transcriptional repressor transcription regulation 96.6 2.1E-05 71-106 / 14-48
phrog_6288 no annotation unknown function 97.0 3.7E-06 64-117 / 14-69
phrog_638 transcriptional regulator transcription regulation 95.4 0.00078 68-119 / 9-61
phrog_6463 HTH DNA binding protein DNA, RNA and nucleotide metabolism 97.1 3E-06 47-120 / 16-87
phrog_6499 transcriptional regulator transcription regulation 90.9 0.045 69-116 / 14-67
phrog_66 excisionase and transcriptional regulator integration and excision 90.1 0.062 74-99 / 9-34
phrog_6831 transcriptional regulator transcription regulation 97.4 3.8E-07 72-113 / 13-56
phrog_686 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.3 0.058 58-98 / 19-61
phrog_6962 no annotation unknown function 95.4 0.00074 65-100 / 5-40
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.4 0.02 72-95 / 42-65
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.7 0.0004 70-116 / 25-72
phrog_7396 no annotation unknown function 92.7 0.017 67-120 / 18-73
phrog_769 transcriptional repressor transcription regulation 94.8 0.002 67-120 / 19-68
phrog_7950 transcriptional repressor transcription regulation 95.1 0.0013 65-98 / 13-46
phrog_8038 no annotation unknown function 91.6 0.031 75-105 / 14-44
phrog_8 transcriptional regulator transcription regulation 98.5 1E-10 66-121 / 6-59
phrog_9103 transcriptional repressor transcription regulation 96.7 1.7E-05 59-121 / 5-67
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.4 5.5E-05 65-109 / 40-84
phrog_9908 DNA binding protein DNA, RNA and nucleotide metabolism 92.0 0.025 65-120 / 18-73

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 5.1E-08 57-128 / 9-79
PF01381.21 Helix-turn-helix 9.6E-08 71-123 / 2-54
PF13744.5 Helix-turn-helix domain 1.6E-07 57-125 / 17-79
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 1.7E-07 71-127 / 4-60
PF13443.5 Cro/C1-type HTH DNA-binding domain 1.7E-07 71-127 / 3-62
PF05339.10 Protein of unknown function (DUF739) 2.1E-07 71-127 / 9-65
PF13413.5 Helix-turn-helix domain 2.2E-07 71-122 / 2-59
PF12844.6 Helix-turn-helix domain 6.1E-07 71-127 / 5-61
PF14590.5 Domain of unknown function (DUF4447) 8.3E-07 71-127 / 13-72
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1.3E-06 71-126 / 75-129
PF13560.5 Helix-turn-helix domain 1.4E-06 71-124 / 7-63
PF04645.11 Protein of unknown function, DUF603 2.3E-06 58-126 / 7-68
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 2.2E-06 71-127 / 2-57
PF08965.9 Domain of unknown function (DUF1870) 5.9E-06 71-119 / 7-57
PF08667.9 BetR domain 6.1E-06 71-127 / 11-71
PF14549.5 DNA-binding transcriptional regulator Cro 8.7E-06 71-126 / 3-54
PF05269.10 Bacteriophage CII protein 9.3E-06 72-128 / 17-71
PF13693.5 Winged helix-turn-helix DNA-binding 2.3E-05 71-127 / 8-61
PF12116.7 Stage III sporulation protein D 0.00012 76-121 / 17-63
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00012 71-118 / 119-166
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00013 71-118 / 13-64
PF00356.20 Bacterial regulatory proteins, lacI family 0.00017 80-116 / 1-37
PF02376.14 CUT domain 0.00029 71-127 / 13-68
PF10654.8 Protein of unknown function (DUF2481) 0.00053 75-103 / 77-105
PF08535.9 KorB domain 0.0045 77-103 / 2-28
PF02042.14 RWP-RK domain 0.0046 71-102 / 5-36

Annotations of the NCBI proteins of this PHROG


1:helix-turn-helix transcriptional regulator 1:DNA-binding protein 1:hypothetical protein 1:transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated

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