phrog_7325 is made of 16 protein sequences and is annotated as "CopG-like transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
83.94 161 81


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_013587_p22 YP_003331472.1 CopG-like RHH protein NC_013587 Sulfolobus spindle-shaped virus 6 (SSV6) Viruses; Fuselloviridae; Betafusellovirus.
KY579375_p18 AQQ16876.1 ORF24 KY579375 Sulfolobus spindle-shaped virus 3 Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
NC_009986_p26 YP_001552204.1 putative RHH protein, CopG family NC_009986 Sulfolobus spindle-shaped virus 4 (SSV4) Viruses; Fuselloviridae; Alphafusellovirus.
NC_005361_p17 NP_963983.1 ribbon-helix-helix domain containing protein NC_005361 Sulfolobus virus Kamchatka 1 Viruses; Fuselloviridae; Alphafusellovirus.
NC_005265_p18 NP_944470.1 ribbon-helix-helix domain containing protein NC_005265 Sulfolobus spindle-shaped virus 2 Viruses; Fuselloviridae; Alphafusellovirus.
NC_001338_p15 NP_039791.1 ORF C-80 NC_001338 Sulfolobus spindle-shaped virus 1 Viruses; Fuselloviridae; Alphafusellovirus.
NC_011217_p26 YP_002221491.1 CopG family NC_011217 Sulfolobus spindle-shaped virus 5 (SSV5) Viruses; Fuselloviridae; Alphafusellovirus.
p417120 no NCBI prot ID no annotation VI_04041 Thermoprotei_gi_229577818_1585865_1598038 Viruses; Fuselloviridae.
p395701 no NCBI prot ID no annotation VI_04040 Thermoprotei_gi_227826411_1679190_1693805 Viruses; Fuselloviridae.
KY563228_p25 AQQ16844.1 B65 KY563228 Sulfolobus spindle-shaped virus Lassen Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
NC_005360_p22 NP_963947.1 ribbon-helix-helix domain containing protein NC_005360 Sulfolobus virus Ragged Hills Viruses; Fuselloviridae; Alphafusellovirus.
NC_013588_p20 YP_003331503.1 CopG-like RHH protein NC_013588 Sulfolobus spindle-shaped virus 7 (SSV7) Viruses; Fuselloviridae; Alphafusellovirus.
NC_005892_p21 YP_025009.1 hypothetical protein NC_005892 Sulfolobus turreted icosahedral virus 1 Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; Belfryvirales; Turriviridae; Alphaturrivirus.
NC_014099_p22 YP_003591096.1 hypothetical protein NC_014099 Sulfolobus turreted icosahedral virus 2 Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; Belfryvirales; Turriviridae; Alphaturrivirus.
NC_028268_p48 YP_009177778.1 hypothetical protein NC_028268 Aeropyrum pernix spindle-shaped virus 1 Viruses; unclassified viruses; unclassified archaeal viruses.
LC208019_p21 BBC20947.1 hypothetical putative RHH DNA-binding protein LC208019 Aeropyrum globular virus 1 Viruses; unclassified archaeal viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_9929 11 zinc-finger domain protein other 10 1.64E-50 40.91
phrog_20741 4 no annotation unknown function 3 1.32E-18 9.0
phrog_20170 4 no annotation unknown function 3 1.32E-18 9.0
phrog_4746 28 no annotation unknown function 2 1.34E-10 1.0
phrog_30450 2 no annotation unknown function 2 0 1000
phrog_4902 27 no annotation unknown function 2 1.19E-10 1.04

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_12301 transcriptional regulator transcription regulation 97.1 1.9E-06 34-73 / 49-88
phrog_13890 no annotation unknown function 90.0 0.064 38-77 / 16-55
phrog_15666 no annotation unknown function 94.9 0.0017 42-79 / 7-42
phrog_19583 no annotation unknown function 91.1 0.041 41-76 / 8-43
phrog_22338 no annotation unknown function 93.8 0.0065 41-79 / 57-95
phrog_22505 no annotation unknown function 92.9 0.014 41-75 / 8-42
phrog_228 Arc-like repressor transcription regulation 95.4 0.00069 38-78 / 6-46
phrog_25971 no annotation unknown function 94.9 0.0018 40-79 / 74-113
phrog_26359 no annotation unknown function 95.9 0.00021 36-78 / 52-94
phrog_2737 no annotation unknown function 91.5 0.033 41-77 / 6-42
phrog_3180 Arc-like repressor transcription regulation 93.0 0.014 41-79 / 7-45
phrog_38469 no annotation unknown function 90.5 0.052 39-79 / 1-37
phrog_3887 transcriptional regulator transcription regulation 96.7 1.3E-05 36-78 / 15-57
phrog_4085 no annotation unknown function 95.1 0.0012 41-79 / 2-39
phrog_4738 transcriptional repressor transcription regulation 96.7 1.4E-05 39-78 / 14-53
phrog_5333 no annotation unknown function 90.5 0.054 39-77 / 1-39
phrog_582 Arc-like repressor transcription regulation 97.0 3.5E-06 41-79 / 7-45
phrog_6506 Arc-like repressor transcription regulation 91.0 0.042 40-78 / 7-45
phrog_876 transcriptional repressor transcription regulation 98.1 4.7E-09 38-79 / 15-56
phrog_9615 no annotation unknown function 94.0 0.0053 40-78 / 210-248

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05534.11 HicB family 9E-09 25-85 / 1-51
PF16777.4 Transcriptional regulator, RHH-like, CopG 1.6E-07 54-92 / 1-39
PF05509.10 TraY domain 2.1E-07 54-90 / 1-37
PF09274.9 ParG 2.2E-07 49-92 / 30-73
PF03869.13 Arc-like DNA binding domain 2.8E-07 50-92 / 3-45
PF09386.9 Antitoxin ParD 8.7E-07 51-92 / 1-42
PF07878.10 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 1.1E-06 52-91 / 2-41
PF01402.20 Ribbon-helix-helix protein, copG family 2.2E-06 53-90 / 1-39
PF09957.8 Bacterial antitoxin of type II TA system, VapB 2.5E-06 53-94 / 2-41
PF12651.6 Ribbon-helix-helix domain 2.5E-06 52-91 / 3-42
PF12441.7 CopG antitoxin of type II toxin-antitoxin system 3.9E-06 50-87 / 38-75
PF04221.11 RelB antitoxin 4.3E-06 52-93 / 2-43
PF03693.13 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 1.4E-05 51-93 / 2-45
PF08681.10 Protein of unknown function (DUF1778) 6.8E-05 53-91 / 1-39
PF15919.4 HicB_like antitoxin of bacterial toxin-antitoxin system 8.6E-05 13-84 / 33-126
PF10723.8 Replication regulatory protein RepB 0.00012 50-90 / 38-78
PF14384.5 BrnA antitoxin of type II toxin-antitoxin system 0.00025 49-89 / 42-78
PF17206.2 SeqA protein N-terminal domain 0.00028 55-86 / 3-34
PF16762.4 Ribbon-helix-helix domain 0.00057 51-93 / 2-47
PF07362.11 Post-segregation antitoxin CcdA 0.0012 52-93 / 2-39
PF07328.10 T-DNA border endonuclease VirD1 0.0057 49-87 / 19-57
PF13467.5 Ribbon-helix-helix domain 0.0084 51-85 / 9-43

Annotations of the NCBI proteins of this PHROG


4:hypothetical protein 3:ribbon-helix-helix domain containing protein 2:protein of an unannotated phage 2:CopG-like RHH protein 1:CopG family 1:hypothetical RHH DNA-binding protein 1:RHH protein, CopG family

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006276 plasmid maintenance
GO:0004519 endonuclease activity
GO:0006355 regulation of transcription, DNA-templated
GO:0000746 conjugation
GO:0003677 DNA binding

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