phrog_7370 is made of 16 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
120.81 195 116


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_027394_p48 YP_009152847.1 HNH homing endonuclease NC_027394 Bacillus phage Pookie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_028926_p46 YP_009210081.1 HNH homing endonuclease NC_028926 Bacillus phage Palmer Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_022764_p46 YP_008770553.1 HNH homing endonuclease NC_022764 Bacillus phage Page Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_029069_p52 YP_009223202.1 hypothetical protein NC_029069 Bacillus phage BM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
KY565347_p59 AQY55079.1 HNH homing endonuclease KY565347 Geobacillus phage TP-84 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Saundersvirus; Geobacillus virus Tp84.
NC_028969_p76 YP_009215090.1 hypothetical protein NC_028969 Brevibacillus phage Osiris Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Jimmervirus.
NC_022980_p68 YP_008858703.1 hypothetical protein NC_022980 Brevibacillus phage Davies Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Abouovirus.
NC_029029_p64 YP_009220121.1 hypothetical protein NC_029029 Brevibacillus phage Abouo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Abouovirus.
KT151958_p76 ALA48086.1 hypothetical protein KT151958 Brevibacillus phage Powder Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Jimmervirus; Brevibacillus virus Osiris; Brevibacillus phage Osiris.
NC_029104_p76 YP_009226386.1 hypothetical protein NC_029104 Brevibacillus phage Jimmer1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Jimmervirus; unclassified Jimmervirus.
KC595514_p76 AGR47242.2 hypothetical protein KC595514 Brevibacillus phage Jimmer2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Jimmervirus; Brevibacillus virus Jimmer.
NC_021558_p36 YP_008129902.1 hypothetical protein NC_021558 Paenibacillus phage PG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_028782_p46 YP_009197515.1 HNH homing endonuclease NC_028782 Bacillus phage Pavlov Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus; unclassified Pagevirus.
NC_022770_p45 YP_008771363.1 HNH endonulease protein NC_022770 Bacillus phage Pony Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_028746_p64 YP_009193877.1 hypothetical protein NC_028746 Paenibacillus phage Harrison Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Harrisonvirus.
p130839 no NCBI prot ID no annotation VI_01276 Clostridia_gi_548232719 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_44 1487 single strand DNA binding protein DNA, RNA and nucleotide metabolism 6 1.08E-13 4.09
phrog_13852 7 no annotation unknown function 6 3.55E-32 22.57
phrog_17768 5 replication initiation protein DNA, RNA and nucleotide metabolism 4 4.09E-23 13.51
phrog_19992 4 no annotation unknown function 4 0 1000
phrog_16826 5 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 2 4.08E-13 3.51

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 5.7E-08 32-89 / 22-85
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.3E-05 28-85 / 134-199
phrog_131 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0096 47-107 / 21-85
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.6E-07 28-86 / 3-64
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.5E-07 30-86 / 51-113
phrog_15103 no annotation unknown function 97.1 1.9E-06 28-89 / 187-257
phrog_15522 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00068 36-90 / 22-84
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 31-83 / 70-127
phrog_16986 no annotation unknown function 95.4 0.00066 25-81 / 4-63
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00025 27-84 / 2-72
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 7E-07 33-82 / 27-76
phrog_22514 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 3.5E-13 3-86 / 2-111
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 97.4 4.6E-07 31-86 / 8-65
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0094 55-86 / 129-160
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 93.8 0.0066 41-83 / 10-66
phrog_28142 HNH endonuclease DNA, RNA and nucleotide metabolism 90.1 0.062 30-85 / 8-76
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 93.5 0.0089 24-86 / 44-106
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 7.8E-06 42-84 / 73-115
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.4E-05 32-86 / 19-73
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 37-85 / 24-82
phrog_3497 no annotation unknown function 95.9 0.00021 38-106 / 23-124
phrog_4581 terminase small subunit head and packaging 96.5 3.3E-05 31-86 / 52-108
phrog_5034 NinG/ Rap DNA junction specific endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 29-87 / 9-71
phrog_5200 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.01 1-86 / 1-87
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 8.3E-05 29-82 / 11-67
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 2.3E-09 26-86 / 35-99
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.9E-06 36-86 / 1-57
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 5.9E-05 40-85 / 4-53
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0056 31-86 / 5-56
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 8.2E-13 25-90 / 2-73
phrog_7566 no annotation unknown function 95.0 0.0014 36-83 / 4-53
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.3E-08 13-86 / 37-112
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.3E-06 23-82 / 9-75
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 1.9E-05 34-87 / 122-188
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00026 11-81 / 78-150
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.6E-05 24-81 / 93-162
phrog_96 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 1.9E-05 42-100 / 256-316

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 3E-07 81-124 / 1-51
PF05315.10 ICEA Protein 4.7E-07 63-123 / 78-149
PF01844.22 HNH endonuclease 5.4E-07 81-122 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 2E-06 67-124 / 75-136
PF13391.5 HNH endonuclease 3.5E-06 81-124 / 1-45
PF14279.5 HNH endonuclease 6.1E-06 81-124 / 1-45
PF06147.10 Protein of unknown function (DUF968) 3.1E-05 77-124 / 126-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 9.7E-05 78-124 / 253-296
PF16784.4 Putative HNHc nuclease 0.00057 77-123 / 122-170

Annotations of the NCBI proteins of this PHROG


9:hypothetical protein 5:HNH homing endonuclease 1:HNH endonulease protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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