phrog_7387 is made of 16 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
115 135 112


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY563228_p36 AQQ16854.1 C123 KY563228 Sulfolobus spindle-shaped virus Lassen Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
p395694 no NCBI prot ID no annotation VI_04040 Thermoprotei_gi_227826411_1679190_1693805 Viruses; Fuselloviridae.
p120324 no NCBI prot ID no annotation VI_12480 Thermoprotei_gi_483378806_339141_382559 Viruses; Fuselloviridae; Alphafusellovirus.
NC_005361_p29 NP_963995.1 putative HTH transcription regulator NC_005361 Sulfolobus virus Kamchatka 1 Viruses; Fuselloviridae; Alphafusellovirus.
p442944 no NCBI prot ID no annotation VI_12476 Thermoprotei_gi_254499611 Viruses; Fuselloviridae; Alphafusellovirus.
NC_005360_p35 NP_963960.1 putative HTH transcription regulator NC_005360 Sulfolobus virus Ragged Hills Viruses; Fuselloviridae; Alphafusellovirus.
KY579375_p29 AQQ16887.1 ORF37 KY579375 Sulfolobus spindle-shaped virus 3 Viruses; Fuselloviridae; Alphafusellovirus; unclassified Alphafusellovirus.
NC_009986_p4 YP_001552182.1 putative HTH-5 transcription regulator NC_009986 Sulfolobus spindle-shaped virus 4 (SSV4) Viruses; Fuselloviridae; Alphafusellovirus.
NC_005265_p29 NP_944481.1 putative HTH transcription regulator NC_005265 Sulfolobus spindle-shaped virus 2 Viruses; Fuselloviridae; Alphafusellovirus.
p417114 no NCBI prot ID no annotation VI_04041 Thermoprotei_gi_229577818_1585865_1598038 Viruses; Fuselloviridae.
NC_011217_p4 YP_002221469.1 putative HTH-5 transcription regulator NC_011217 Sulfolobus spindle-shaped virus 5 (SSV5) Viruses; Fuselloviridae; Alphafusellovirus.
NC_013588_p31 YP_003331514.1 putative HTH transcriptional regulator NC_013588 Sulfolobus spindle-shaped virus 7 (SSV7) Viruses; Fuselloviridae; Alphafusellovirus.
p120267 no NCBI prot ID no annotation VI_12478 Thermoprotei_gi_483377487_338515_381935 Viruses; Fuselloviridae; Alphafusellovirus.
p388683 no NCBI prot ID no annotation VI_04039 Thermoprotei_gi_227829020_118353_133781 Viruses; Fuselloviridae.
p370716 no NCBI prot ID no annotation VI_04038 Thermoprotei_gi_374633285_291125_308527 Viruses; Fuselloviridae; Alphafusellovirus.
NC_020882_p21 YP_007678023.1 putative transcriptional regulator NC_020882 Sulfolobales Mexican fusellovirus 1 (SMF1) Viruses; Fuselloviridae; unclassified Fuselloviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8228 14 no annotation unknown function 11 2.18E-53 43.78
phrog_5402 24 virion structural protein head and packaging 9 9.05E-40 30.16
phrog_11172 9 virion structural protein head and packaging 7 6.65E-36 26.3
phrog_6801 17 no annotation unknown function 4 2.14E-19 9.79

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_2440 transcriptional regulator transcription regulation 94.6 0.0026 12-66 / 10-64
phrog_32717 transcriptional regulator transcription regulation 99.4 5.4E-17 5-77 / 5-77
phrog_436 no annotation unknown function 94.8 0.002 7-71 / 5-77

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 1.2E-07 21-81 / 23-91
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 1.6E-07 23-73 / 6-56
PF03965.15 Penicillinase repressor 1.8E-07 26-82 / 4-66
PF02334.15 Replication terminator protein 3.7E-07 27-97 / 20-105
PF14557.5 Putative AphA-like transcriptional regulator 3.7E-07 23-95 / 6-90
PF02319.19 E2F/DP family winged-helix DNA-binding domain 4.1E-07 29-73 / 11-57
PF06163.10 Bacterial protein of unknown function (DUF977) 4.8E-07 23-82 / 10-69
PF11313.7 Protein of unknown function (DUF3116) 5E-07 29-93 / 11-80
PF14277.5 Domain of unknown function (DUF4364) 5.1E-07 28-82 / 3-62
PF08222.10 CodY helix-turn-helix domain 5.7E-07 39-74 / 4-39
PF07381.10 Winged helix DNA-binding domain (DUF1495) 5.9E-07 22-73 / 6-68
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 8.8E-07 28-82 / 4-61
PF14394.5 Domain of unknown function (DUF4423) 8.8E-07 21-74 / 17-73
PF09114.9 Transcription factor MotA, activation domain 1.3E-06 21-73 / 12-65
PF04079.15 Segregation and condensation complex subunit ScpB 1.8E-06 21-90 / 79-147
PF13601.5 Winged helix DNA-binding domain 1.9E-06 29-74 / 4-49
PF05584.10 Sulfolobus plasmid regulatory protein 1.9E-06 30-73 / 10-52
PF01090.18 Ribosomal protein S19e 1.9E-06 28-74 / 54-115
PF01978.18 Sugar-specific transcriptional regulator TrmB 2E-06 25-74 / 8-57
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 2E-06 23-72 / 11-60
PF02002.16 TFIIE alpha subunit 2.1E-06 26-74 / 13-61
PF02295.16 Adenosine deaminase z-alpha domain 2.3E-06 28-73 / 7-53
PF09012.9 FeoC like transcriptional regulator 2.3E-06 32-75 / 7-50
PF03551.13 Transcriptional regulator PadR-like family 2.5E-06 38-74 / 13-51
PF12793.6 Sugar transport-related sRNA regulator N-term 2.9E-06 29-73 / 6-52
PF01475.18 Ferric uptake regulator family 3.7E-06 23-83 / 5-72
PF03428.12 Replication protein C N-terminal domain 5.2E-06 19-74 / 37-106
PF16221.4 winged helix-turn-helix 5.2E-06 26-71 / 32-78
PF13463.5 Winged helix DNA-binding domain 6.2E-06 27-73 / 5-51
PF08784.10 Replication protein A C terminal 6.6E-06 25-73 / 40-95
PF09904.8 Winged helix-turn helix 8.4E-06 29-71 / 11-53
PF14947.5 Winged helix-turn-helix 9.5E-06 28-73 / 5-50
PF09824.8 ArsR transcriptional regulator 9.7E-06 19-72 / 11-61
PF05158.11 RNA polymerase Rpc34 subunit 0.0074 23-81 / 11-77
PF10771.8 Winged helix-turn-helix domain (DUF2582) 1.1E-05 25-76 / 8-59
PF09639.9 YjcQ protein 1.2E-05 38-73 / 15-52
PF09202.10 Rio2, N-terminal 1.2E-05 27-73 / 8-58
PF01726.15 LexA DNA binding domain 1.3E-05 39-73 / 25-60
PF01638.16 HxlR-like helix-turn-helix 1.3E-05 27-74 / 7-55
PF04182.11 B-block binding subunit of TFIIIC 1.4E-05 29-74 / 6-53
PF05732.10 Firmicute plasmid replication protein (RepL) 1.5E-05 25-73 / 55-109
PF12840.6 Helix-turn-helix domain 1.6E-05 24-73 / 7-54
PF07848.11 PaaX-like protein 1.6E-05 38-80 / 19-64
PF12802.6 MarR family 1.9E-05 40-73 / 22-55
PF02082.19 Transcriptional regulator 2E-05 40-73 / 25-58
PF13034.5 Protein of unknown function (DUF3895) 2.1E-05 26-74 / 4-68
PF10711.8 Hypothetical protein (DUF2513) 2.6E-05 28-74 / 8-57
PF01047.21 MarR family 2.8E-05 30-73 / 8-51
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 3.4E-05 24-95 / 4-80
PF01022.19 Bacterial regulatory protein, arsR family 4.6E-05 30-69 / 7-46
PF13412.5 Winged helix-turn-helix DNA-binding 4.6E-05 30-69 / 8-47
PF09182.9 Bacterial purine repressor, N-terminal 4.6E-05 28-72 / 7-58
PF01316.20 Arginine repressor, DNA binding domain 4.8E-05 28-76 / 8-58
PF09339.9 IclR helix-turn-helix domain 4.9E-05 40-72 / 19-51
PF04703.11 FaeA-like protein 5E-05 30-73 / 5-48
PF00392.20 Bacterial regulatory proteins, gntR family 5.6E-05 37-73 / 21-58
PF03297.14 S25 ribosomal protein 7.2E-05 29-72 / 46-89
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 9.5E-05 38-73 / 23-58
PF11972.7 HTH DNA binding domain 0.00013 31-70 / 5-41
PF06969.15 HemN C-terminal domain 0.00013 29-72 / 10-54
PF08220.11 DeoR-like helix-turn-helix domain 0.00015 32-73 / 7-48
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00015 38-72 / 16-50
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.00017 27-73 / 10-60
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00018 38-73 / 20-55
PF14502.5 Helix-turn-helix domain 0.0002 39-73 / 6-40
PF15977.4 Winged helix-turn-helix DNA binding 0.00021 39-73 / 23-57
PF16864.4 Dimerisation domain 0.00021 26-72 / 19-65
PF08461.9 Ribonuclease R winged-helix domain 0.00025 38-73 / 11-51
PF05331.10 Protein of unknown function (DUF742) 0.00028 25-74 / 41-88
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00045 41-72 / 13-47
PF05043.12 Mga helix-turn-helix domain 0.0005 24-66 / 15-57
PF09756.8 DDRGK domain 0.00058 30-96 / 106-170
PF01418.16 Helix-turn-helix domain, rpiR family 0.00061 39-72 / 34-67
PF13545.5 Crp-like helix-turn-helix domain 0.00064 39-71 / 27-59
PF07900.10 Protein of unknown function (DUF1670) 0.00065 38-73 / 94-129
PF08279.11 HTH domain 0.00077 38-67 / 14-43
PF07183.10 Protein of unknown function (DUF1403) 0.00077 26-73 / 275-320
PF09397.9 Ftsk gamma domain 0.00084 33-73 / 13-53
PF13730.5 Helix-turn-helix domain 0.0011 50-69 / 33-52
PF13404.5 AsnC-type helix-turn-helix domain 0.0012 38-63 / 16-41
PF17443.1 Uncharacterized protein pXO2-72 0.0012 39-72 / 8-50
PF08679.10 Dissimilatory sulfite reductase D (DsrD) 0.0015 29-80 / 4-58
PF16509.4 TrfB plasmid transcriptional repressor 0.0017 39-72 / 31-63
PF00325.19 Bacterial regulatory proteins, crp family 0.0018 41-69 / 4-32
PF08535.9 KorB domain 0.0022 39-73 / 3-37
PF06971.12 Putative DNA-binding protein N-terminus 0.0033 29-60 / 15-48
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0035 41-63 / 53-75
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 0.0043 40-72 / 54-86
PF14338.5 Mrr N-terminal domain 0.0049 50-90 / 48-83
PF02954.18 Bacterial regulatory protein, Fis family 0.006 39-62 / 16-39
PF07037.10 Putative transcription regulator (DUF1323) 0.0068 41-69 / 2-27
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0082 30-66 / 10-47

Annotations of the NCBI proteins of this PHROG


3:HTH transcription regulator 2:hypothetical protein 2:HTH-5 transcription regulator 1:transcriptional regulator 1:HTH transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0009289 pilus
GO:0006260 DNA replication
GO:0004674 protein serine/threonine kinase activity
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0003700 DNA binding transcription factor activity
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0003723 RNA binding
GO:0051775 response to redox state
GO:0003735 structural constituent of ribosome
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051304 chromosome separation
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0005666 DNA-directed RNA polymerase III complex
GO:0043565 sequence-specific DNA binding
GO:0006508 proteolysis
GO:0006276 plasmid maintenance
GO:0005524 ATP binding

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