phrog_7426 is made of 16 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
147.88 153 145


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF155946_p22 ASR75430.1 HNH endonuclease MF155946 Streptomyces phage Mildred21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Mildred21.
NC_029098_p26 YP_009225752.1 HNH endonuclease NC_029098 Streptomyces phage Jay2Jay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Jay2Jay.
MF347638_p23 ASR77730.1 HNH endonuclease MF347638 Streptomyces phage Peebs Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Peebs.
MF347636_p22 ASR77292.1 HNH endonuclease MF347636 Streptomyces phage NootNoot Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus NootNoot.
MF358541_p233 ASN73308.1 HNH endonuclease MF358541 Streptomyces phage Warpy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF358542_p24 ASR76457.1 HNH endonuclease MF358542 Streptomyces phage Sushi23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF347639_p21 AST15253.1 HNH endonuclease MF347639 Streptomyces phage Samisti12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Samisti12.
MF347638_p226 ASR77933.1 HNH endonuclease MF347638 Streptomyces phage Peebs Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Peebs.
MF155946_p234 ASR75642.1 HNH endonuclease MF155946 Streptomyces phage Mildred21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Mildred21.
MF347636_p221 ASR77489.1 HNH endonuclease MF347636 Streptomyces phage NootNoot Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus NootNoot.
MF358542_p229 ASR76658.1 HNH endonuclease MF358542 Streptomyces phage Sushi23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF347637_p216 ASR77691.1 HNH endonuclease MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.
MF347637_p22 ASR77513.1 HNH endonuclease MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.
NC_029098_p235 YP_009225961.1 HNH endonuclease NC_029098 Streptomyces phage Jay2Jay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Jay2Jay.
MF347639_p226 AST15457.1 HNH endonuclease MF347639 Streptomyces phage Samisti12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Samisti12.
MF358541_p26 ASN73101.1 HNH endonuclease MF358541 Streptomyces phage Warpy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 94.1 0.0047 45-107 / 36-88
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.034 20-98 / 49-111

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 4.3E-08 74-107 / 18-51
PF01844.22 HNH endonuclease 6.4E-08 55-106 / 1-47
PF05315.10 ICEA Protein 5.3E-07 50-106 / 91-149
PF13391.5 HNH endonuclease 5.5E-07 73-108 / 11-46
PF14279.5 HNH endonuclease 2E-06 55-107 / 1-45
PF06147.10 Protein of unknown function (DUF968) 2.2E-06 50-107 / 125-174
PF05766.11 Bacteriophage Lambda NinG protein 3.5E-06 52-107 / 87-136
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00019 52-107 / 253-296
PF16784.4 Putative HNHc nuclease 0.00031 51-107 / 122-171

Annotations of the NCBI proteins of this PHROG


16:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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