phrog_7785 is made of 15 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
139.27 191 143


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX557288_p37 AON97459.1 HNH endonuclease KX557288 Rhodococcus phage ChewyVIII Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MG757166_p24 AVE00682.1 HNH endonuclease MG757166 Gordonia phage SuperSulley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MG757157_p27 AVD99771.1 HNH endonuclease MG757157 Gordonia phage Flapper Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF919510_p26 ATN89547.1 HNH endonuclease MF919510 Gordonia phage Kabluna Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MG198780_p11 ATW58840.1 HNH endonuclease MG198780 Corynebacterium phage Zion Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ceetrepovirus; Corynebacterium virus Zion.
NC_016434_p14 YP_004935745.1 terminase small subunit NC_016434 Gordonia phage GTE5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MG198776_p11 ATW58514.1 hypothetical protein MG198776 Corynebacterium phage C3PO Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ceetrepovirus; Corynebacterium virus C3PO.
MG198777_p13 ATW58574.1 hypothetical protein MG198777 Corynebacterium phage Darwin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ceetrepovirus; Corynebacterium virus Darwin.
NC_028653_p12 YP_009187074.1 putative small terminase subunit NC_028653 Gordonia phage GTE8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_016435_p13 YP_004935836.1 terminase small subunit NC_016435 Gordonia phage GRU1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF919542_p26 ATS93108.1 HNH endonuclease MF919542 Gordonia phage Patio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p215463 no NCBI prot ID no annotation VI_01009 Bacteroidia_gi_333463429 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p275052 no NCBI prot ID no annotation VI_05495 Bacteroidia_gi_484226193 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p70816 no NCBI prot ID no annotation VI_05598 Betaproteobacteria_gi_483587362_3686_53282 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p309684 no NCBI prot ID no annotation VI_04250 Alphaproteobacteria_gi_402821110_8504_33206 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_9 2977 terminase large subunit head and packaging 10 2.63E-20 10.7
phrog_18398 5 no annotation unknown function 5 0 1000
phrog_13218 7 no annotation unknown function 2 1.17E-12 3.05
phrog_33862 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10212 no annotation unknown function 91.8 0.029 58-112 / 53-124
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.6 1.9E-11 54-117 / 87-158
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 95.1 0.0013 49-110 / 88-151
phrog_10822 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0021 67-108 / 98-145
phrog_11604 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 9.3E-05 58-112 / 65-131
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 1.7E-10 60-112 / 23-82
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 1.1E-05 67-112 / 27-89
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 2.2E-09 65-112 / 143-200
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 2.3E-15 62-112 / 10-64
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 4.8E-14 59-117 / 53-118
phrog_15103 no annotation unknown function 96.6 2.7E-05 49-108 / 181-250
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00018 58-112 / 121-182
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 6.2E-10 59-117 / 71-137
phrog_16986 no annotation unknown function 98.0 1E-08 63-112 / 15-68
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00013 79-112 / 9-43
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.9E-06 65-118 / 64-134
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 1.8E-11 54-127 / 2-89
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 8.7E-14 61-117 / 28-85
phrog_22283 no annotation unknown function 95.9 0.00019 70-109 / 24-68
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 95.5 0.00054 67-117 / 64-132
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.7E-06 67-116 / 23-94
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 90.4 0.054 72-121 / 82-141
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 96.2 8.8E-05 53-109 / 2-62
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.013 79-112 / 127-160
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3.6E-05 68-117 / 10-79
phrog_26098 no annotation unknown function 95.8 0.00027 58-114 / 124-188
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 96.7 1.5E-05 49-112 / 19-81
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00038 59-109 / 51-103
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00082 59-112 / 34-106
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 68-118 / 72-124
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 6E-14 51-116 / 8-77
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 91.8 0.028 69-112 / 20-75
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.8 4.5E-12 64-113 / 24-84
phrog_4160 no annotation unknown function 91.6 0.033 67-111 / 59-116
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 95.1 0.0012 68-114 / 27-85
phrog_4581 terminase small subunit head and packaging 98.3 9.7E-10 59-113 / 53-109
phrog_4590 no annotation unknown function 91.4 0.036 78-110 / 51-83
phrog_5104 no annotation unknown function 93.2 0.011 49-116 / 124-201
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 3.3E-14 59-112 / 14-71
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 2.7E-16 59-116 / 41-103
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 2.8E-08 63-119 / 1-65
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 9E-15 67-115 / 4-57
phrog_6544 no annotation unknown function 93.0 0.013 57-112 / 15-71
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0056 79-110 / 23-54
phrog_7275 no annotation unknown function 96.7 1.2E-05 78-119 / 6-47
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 2.6E-08 48-112 / 21-86
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.2E-07 54-112 / 4-69
phrog_7426 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.06 49-111 / 20-98
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.4E-05 49-111 / 8-78
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 1E-06 60-113 / 121-188
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 7.4E-12 62-112 / 104-155
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00029 70-112 / 22-74
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.1E-06 59-125 / 101-179
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 93.2 0.012 69-112 / 40-87
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 5.3E-08 58-112 / 14-75

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 4.2E-08 71-127 / 75-136
PF05315.10 ICEA Protein 2.7E-07 69-126 / 80-149
PF13395.5 HNH endonuclease 3.6E-07 94-127 / 18-51
PF01844.22 HNH endonuclease 4.7E-07 85-125 / 1-46
PF13391.5 HNH endonuclease 2E-06 85-128 / 1-46
PF14279.5 HNH endonuclease 3.5E-06 85-127 / 1-45
PF06147.10 Protein of unknown function (DUF968) 5.5E-06 80-127 / 125-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 6.4E-05 82-128 / 253-297
PF16784.4 Putative HNHc nuclease 0.00043 80-127 / 121-171

Annotations of the NCBI proteins of this PHROG


6:HNH endonuclease 2:hypothetical protein 2:terminase small subunit 1:small terminase subunit

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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