phrog_7950 is made of 14 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
70.86 94 71


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p141193 no NCBI prot ID no annotation VI_04895 Bacilli_gi_421228548 Viruses; unclassified bacterial viruses.
KY065478_p8 APD23100.1 DNA-binding protein KY065478 Streptococcus phage IPP38 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p318019 no NCBI prot ID no annotation VI_05715 Betaproteobacteria_gi_545068446 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p132974 no NCBI prot ID no annotation VI_11386 Gammaproteobacteria_gi_544850511 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p168721 no NCBI prot ID no annotation VI_02605 Gammaproteobacteria_gi_254361300_6107_45249 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Haemophilus phage SuMu.
NC_028766_p17 YP_009196066.1 hypothetical protein NC_028766 Mannheimia phage vB_MhM_3927AP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p142851 no NCBI prot ID no annotation VI_05553 Betaproteobacteria_gi_338760576_20718_62259 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p290972 no NCBI prot ID no annotation VI_11409 Gammaproteobacteria_gi_544866898 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Haemophilus phage SuMu.
p320923 no NCBI prot ID no annotation VI_11394 Gammaproteobacteria_gi_544850780 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Haemophilus phage SuMu.
p15736 no NCBI prot ID no annotation VI_02972 Gammaproteobacteria_gi_161789109 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p17288 no NCBI prot ID no annotation VI_12016 Gammaproteobacteria_gi_501174973 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p15035 no NCBI prot ID no annotation VI_12104 Gammaproteobacteria_gi_550350159 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p424741 no NCBI prot ID no annotation VI_05593 Betaproteobacteria_gi_421540251 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MG214783_p15 ATS92156.1 putative transcriptional regulator MG214783 Sinorhizobium phage HMSP1-Susan Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_836 173 late transcriptional activator transcription regulation 5 4.65E-18 8.45
phrog_18666 5 no annotation unknown function 5 0 1000
phrog_4865 27 no annotation unknown function 3 5.68E-15 5.37
phrog_6248 19 no annotation unknown function 2 1.41E-11 1.97

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11187 transcriptional regulator transcription regulation 94.7 0.0024 9-68 / 4-61
phrog_1124 transcriptional regulator transcription regulation 91.7 0.03 14-45 / 11-42
phrog_11423 no annotation unknown function 91.8 0.029 19-63 / 19-58
phrog_1373 transcriptional regulator transcription regulation 97.2 1.5E-06 11-53 / 33-75
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 91.3 0.038 19-44 / 20-45
phrog_14076 transcriptional regulator transcription regulation 97.6 1.1E-07 10-48 / 2-43
phrog_14341 transcriptional repressor transcription regulation 96.3 7.7E-05 9-62 / 3-52
phrog_147 transcriptional regulator transcription regulation 95.3 0.00081 11-45 / 4-38
phrog_151 transposase integration and excision 92.4 0.02 8-47 / 6-48
phrog_15481 no annotation unknown function 93.6 0.0082 9-41 / 4-38
phrog_1553 excisionase integration and excision 91.1 0.041 23-45 / 5-27
phrog_16553 transcriptional repressor transcription regulation 90.8 0.046 20-44 / 20-44
phrog_1729 no annotation unknown function 94.9 0.0018 10-45 / 70-107
phrog_1740 RNA polymerase sigma factor transcription regulation 90.7 0.049 17-41 / 137-161
phrog_18342 transcriptional repressor transcription regulation 90.1 0.063 13-45 / 21-53
phrog_1994 DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.0049 13-46 / 3-36
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 92.9 0.015 7-40 / 53-88
phrog_2104 no annotation unknown function 97.8 3E-08 7-63 / 43-96
phrog_2328 transcriptional repressor transcription regulation 96.3 6.4E-05 12-48 / 18-54
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.4 0.00075 13-45 / 28-60
phrog_24325 transcriptional regulator transcription regulation 92.1 0.024 11-45 / 54-88
phrog_2439 transcriptional regulator transcription regulation 96.4 5.1E-05 5-47 / 2-44
phrog_2474 MerR-like transcriptional regulator transcription regulation 94.3 0.0038 23-47 / 16-40
phrog_2538 terminase small subunit head and packaging 96.5 3.9E-05 21-48 / 18-45
phrog_2907 excisionase integration and excision 90.8 0.046 21-47 / 4-30
phrog_2967 transcriptional regulator transcription regulation 95.9 0.00025 7-54 / 6-54
phrog_30764 no annotation unknown function 91.7 0.03 16-52 / 92-128
phrog_309 terminase small subunit head and packaging 93.7 0.0074 13-45 / 13-47
phrog_3218 terminase small subunit head and packaging 90.4 0.055 7-46 / 17-57
phrog_34341 transcriptional regulator transcription regulation 96.2 9.4E-05 10-46 / 72-108
phrog_3512 sigma factor transcription regulation 90.6 0.051 8-42 / 66-102
phrog_351 RNA polymerase sigma factor transcription regulation 92.5 0.019 9-45 / 176-217
phrog_357 transcriptional repressor transcription regulation 92.1 0.025 6-39 / 9-41
phrog_35 transcriptional repressor transcription regulation 92.9 0.014 22-45 / 13-36
phrog_37751 no annotation unknown function 97.9 2.1E-08 9-64 / 136-188
phrog_3 transcriptional repressor transcription regulation 97.1 3E-06 10-45 / 4-39
phrog_4031 no annotation unknown function 90.1 0.061 12-45 / 518-551
phrog_409 transcriptional regulator transcription regulation 95.6 0.00051 17-44 / 6-32
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00013 21-45 / 19-43
phrog_4739 no annotation unknown function 92.0 0.025 10-46 / 68-104
phrog_4745 DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.012 23-47 / 5-29
phrog_4779 transcriptional regulator transcription regulation 96.6 2.6E-05 10-45 / 2-37
phrog_4836 CII-like regulator transcription regulation 96.4 4.6E-05 12-45 / 85-118
phrog_4 transcriptional repressor transcription regulation 93.6 0.0084 20-44 / 12-34
phrog_5119 no annotation unknown function 96.6 2E-05 9-47 / 53-91
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.5 0.00061 9-41 / 64-98
phrog_534 DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.028 19-45 / 22-48
phrog_57 terminase small subunit head and packaging 94.1 0.005 22-47 / 2-27
phrog_5823 transcriptional regulator transcription regulation 94.9 0.0016 11-48 / 6-43
phrog_609 RIIB lysis inhibitor lysis 92.0 0.026 17-48 / 18-49
phrog_6106 no annotation unknown function 94.3 0.004 13-60 / 14-56
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 90.9 0.045 7-41 / 17-53
phrog_6620 transposase integration and excision 92.5 0.019 23-49 / 4-30
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 93.5 0.0085 9-47 / 53-93
phrog_668 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.1 0.024 20-59 / 34-68
phrog_66 excisionase and transcriptional regulator integration and excision 96.1 0.00014 22-47 / 9-34
phrog_6831 transcriptional regulator transcription regulation 95.5 0.00052 20-45 / 13-38
phrog_6962 no annotation unknown function 91.2 0.039 12-47 / 4-39
phrog_7241 transcriptional regulator transcription regulation 95.5 0.00061 13-46 / 65-98
phrog_725 CII-like regulator transcription regulation 92.1 0.024 16-46 / 21-51
phrog_7344 terminase small subunit head and packaging 95.4 0.00071 23-52 / 27-56
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 12-53 / 8-49
phrog_756 DNA binding protein DNA, RNA and nucleotide metabolism 91.9 0.027 20-45 / 17-42
phrog_7676 no annotation unknown function 93.9 0.0059 20-55 / 14-49
phrog_7735 excisionase integration and excision 91.7 0.03 23-58 / 18-52
phrog_8351 no annotation unknown function 93.4 0.0097 15-65 / 30-81
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0023 11-50 / 6-45
phrog_8898 no annotation unknown function 94.8 0.002 11-45 / 3-37
phrog_8 transcriptional regulator transcription regulation 97.2 1.1E-06 12-45 / 4-36
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.4 0.055 12-45 / 39-72
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.9 0.014 17-47 / 12-43

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 1.3E-10 10-80 / 6-77
PF05339.10 Protein of unknown function (DUF739) 7.3E-09 17-81 / 6-65
PF13744.5 Helix-turn-helix domain 1E-08 12-78 / 16-78
PF14590.5 Domain of unknown function (DUF4447) 1.3E-08 13-79 / 6-70
PF01381.21 Helix-turn-helix 1.6E-08 21-77 / 3-54
PF13413.5 Helix-turn-helix domain 2.9E-08 21-76 / 3-59
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 4.5E-08 19-81 / 3-60
PF04645.11 Protein of unknown function, DUF603 7E-08 11-69 / 4-60
PF12844.6 Helix-turn-helix domain 1.3E-07 19-80 / 4-60
PF13560.5 Helix-turn-helix domain 1.8E-07 16-78 / 3-63
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 2E-07 15-79 / 70-128
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.2E-07 20-80 / 3-61
PF08667.9 BetR domain 3.4E-07 14-80 / 5-70
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 6.6E-07 22-80 / 4-56
PF08965.9 Domain of unknown function (DUF1870) 1.3E-06 16-50 / 3-39
PF05269.10 Bacteriophage CII protein 1.7E-06 20-80 / 16-69
PF14549.5 DNA-binding transcriptional regulator Cro 5E-06 20-78 / 3-52
PF13693.5 Winged helix-turn-helix DNA-binding 5.3E-06 18-79 / 6-59
PF12116.7 Stage III sporulation protein D 8.1E-06 22-75 / 14-63
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 1.6E-05 16-71 / 115-165
PF02376.14 CUT domain 5.1E-05 13-80 / 6-67
PF00157.16 Pou domain - N-terminal to homeobox domain 5.2E-05 13-50 / 6-49
PF10654.8 Protein of unknown function (DUF2481) 6.2E-05 24-50 / 77-103
PF00356.20 Bacterial regulatory proteins, lacI family 0.00013 29-50 / 1-22
PF08535.9 KorB domain 0.0009 26-50 / 2-26
PF02042.14 RWP-RK domain 0.0019 20-50 / 5-35
PF06322.10 Phage NinH protein 0.0027 20-50 / 9-39
PF04552.12 Sigma-54, DNA binding domain 0.004 25-50 / 46-71
PF01371.18 Trp repressor protein 0.004 25-50 / 46-71
PF02954.18 Bacterial regulatory protein, Fis family 0.0044 24-49 / 13-38
PF07506.10 RepB plasmid partitioning protein 0.0043 18-50 / 13-44
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0054 26-50 / 12-36
PF06806.11 Putative excisionase (DUF1233) 0.0062 27-50 / 9-32
PF00376.22 MerR family regulatory protein 0.0064 30-50 / 2-22
PF07278.10 Protein of unknown function (DUF1441) 0.0069 27-50 / 1-24
PF07141.10 Putative bacteriophage terminase small subunit 0.007 25-50 / 29-54
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0069 18-50 / 96-130

Annotations of the NCBI proteins of this PHROG


1:hypothetical protein 1:transcriptional regulator 1:DNA-binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0045892 negative regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0003700 DNA binding transcription factor activity
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding

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