phrog_8102 is made of 14 protein sequences and is annotated as "replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
123.07 360 98


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KR091942_p1 AKI28502.1 ankyrin repeat protein KR091942 Salmonella phage 18-India Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_022968_p238 YP_008857454.1 helix-turn-helix DNA-binding domain-containing protein NC_022968 Escherichia phage 4MG Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Seunavirus.
NC_028659_p217 YP_009187830.1 hypothetical protein NC_028659 Klebsiella phage vB_KpnM_KB57 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; unclassified Vequintavirinae.
NC_019400_p36 YP_006986869.1 hypothetical protein NC_019400 Cronobacter phage vB_CsaM_GAP31 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Seunavirus.
MG250486_p31 AUE23257.1 hypothetical protein MG250486 Raoultella phage Ro1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; unclassified Vequintavirinae.
KY652726_p214 ARB12718.1 hypothetical protein KY652726 Klebsiella phage vB_KpnM_BIS47 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; unclassified Vequintavirinae.
NC_016071_p213 YP_004894020.1 hypothetical protein NC_016071 Salmonella phage PVP-SE1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Seunavirus; Salmonella virus PVPSE1.
NC_022968_p94 YP_008857310.1 helix-turn-helix DNA-binding domain-containing protein NC_022968 Escherichia phage 4MG Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Seunavirus.
KY652726_p76 ARB12580.1 hypothetical protein KY652726 Klebsiella phage vB_KpnM_BIS47 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; unclassified Vequintavirinae.
NC_019400_p182 YP_006987015.1 hypothetical protein NC_019400 Cronobacter phage vB_CsaM_GAP31 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Seunavirus.
KU862660_p115 ANA49240.1 hypothetical protein KU862660 Pseudomonas phage phiPMW Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Plaisancevirus; Pseudomonas virus PMW.
p310409 no NCBI prot ID no annotation VI_12473 Synergistia_gi_282856097_5338_29918 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p107 no NCBI prot ID no annotation VI_00733 Bacilli_gi_218847808 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p54090 no NCBI prot ID no annotation VI_06222 Deinococci_gi_484153907 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_6790 17 tail protein tail 6 3.49E-29 19.58
phrog_619 226 ribose-phosphate pyrophosphokinase other 3 2.82E-11 1.67
phrog_6073 20 Rz-like spanin lysis 2 1.44E-11 1.96
phrog_8785 13 no annotation unknown function 2 3.62E-12 2.56

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1032 replication initiation protein DNA, RNA and nucleotide metabolism 98.1 3.1E-09 16-84 / 10-74
phrog_10724 no annotation unknown function 95.4 0.00072 45-84 / 29-68
phrog_1098 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.0 0.0016 51-84 / 43-76
phrog_11233 replication initiation protein DNA, RNA and nucleotide metabolism 93.4 0.0096 41-81 / 41-82
phrog_11896 primosomal protein DNA, RNA and nucleotide metabolism 97.1 2.7E-06 37-89 / 30-86
phrog_11961 no annotation unknown function 91.1 0.041 44-84 / 53-93
phrog_12720 DNA binding protein DNA, RNA and nucleotide metabolism 92.6 0.017 41-78 / 43-80
phrog_12838 replication initiation protein DNA, RNA and nucleotide metabolism 94.5 0.003 13-84 / 25-94
phrog_13105 no annotation unknown function 90.6 0.051 50-82 / 22-54
phrog_1368 transcriptional regulator transcription regulation 94.3 0.0038 49-80 / 30-61
phrog_14053 no annotation unknown function 92.4 0.02 12-84 / 134-210
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00013 47-82 / 12-47
phrog_15053 no annotation unknown function 96.7 1.5E-05 8-93 / 19-106
phrog_15967 no annotation unknown function 90.8 0.047 42-84 / 122-164
phrog_18020 replication initiation O-like DNA, RNA and nucleotide metabolism 94.5 0.003 15-89 / 17-90
phrog_1835 HTH DNA binding protein DNA, RNA and nucleotide metabolism 97.9 1.8E-08 13-94 / 34-123
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 96.9 5.2E-06 21-85 / 24-88
phrog_18890 transcriptional regulator transcription regulation 90.3 0.058 50-94 / 41-87
phrog_19047 transcriptional regulator transcription regulation 96.8 1.2E-05 16-84 / 179-244
phrog_19658 replication initiation protein DNA, RNA and nucleotide metabolism 93.9 0.0062 18-93 / 14-88
phrog_2030 transcriptional regulator transcription regulation 92.9 0.014 23-89 / 17-76
phrog_21732 no annotation unknown function 93.6 0.008 15-94 / 17-94
phrog_21868 no annotation unknown function 94.5 0.0032 29-89 / 42-108
phrog_22534 no annotation unknown function 95.7 0.00038 10-84 / 13-81
phrog_22671 replication protein DNA, RNA and nucleotide metabolism 92.5 0.019 20-84 / 51-118
phrog_2418 no annotation unknown function 93.2 0.011 47-89 / 56-103
phrog_2440 transcriptional regulator transcription regulation 93.0 0.014 19-80 / 6-59
phrog_2514 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 92.0 0.026 41-89 / 49-105
phrog_25806 no annotation unknown function 92.8 0.016 17-83 / 6-64
phrog_26369 replication initiation protein DNA, RNA and nucleotide metabolism 91.2 0.039 43-79 / 75-112
phrog_26991 no annotation unknown function 91.3 0.038 16-89 / 34-109
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 98.0 6E-09 20-84 / 15-75
phrog_27344 replication initiation protein DNA, RNA and nucleotide metabolism 92.2 0.022 18-89 / 14-85
phrog_28562 no annotation unknown function 96.3 6.4E-05 26-83 / 40-93
phrog_30562 no annotation unknown function 96.0 0.00015 19-81 / 16-85
phrog_32108 no annotation unknown function 96.6 2.4E-05 19-90 / 25-96
phrog_32138 DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.017 50-71 / 21-42
phrog_33614 no annotation unknown function 91.8 0.029 32-80 / 56-110
phrog_3396 segregation and condensation complex subunit ScpB DNA, RNA and nucleotide metabolism 95.2 0.0011 49-89 / 59-100
phrog_345 replication initiation O-like DNA, RNA and nucleotide metabolism 95.7 0.00037 21-88 / 46-113
phrog_3502 no annotation unknown function 97.2 1.3E-06 19-83 / 2-62
phrog_36008 no annotation unknown function 96.6 2.2E-05 15-89 / 33-105
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.3 0.037 49-79 / 81-111
phrog_391 replication initiation O-like DNA, RNA and nucleotide metabolism 98.2 2E-09 19-90 / 16-87
phrog_4221 replication initiation protein DNA, RNA and nucleotide metabolism 95.4 0.00069 8-84 / 13-82
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 98.5 8.8E-11 7-91 / 12-95
phrog_4617 replication initiation protein DNA, RNA and nucleotide metabolism 97.0 4.9E-06 22-84 / 15-75
phrog_5978 no annotation unknown function 95.6 0.0005 48-90 / 321-363
phrog_6223 transcriptional repressor transcription regulation 91.7 0.03 20-71 / 2-41
phrog_6336 no annotation unknown function 94.7 0.0024 47-82 / 26-62
phrog_633 transcriptional regulator transcription regulation 91.3 0.038 48-84 / 17-53
phrog_6643 replication initiation protein DNA, RNA and nucleotide metabolism 90.8 0.046 22-84 / 16-74
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 98.0 7.4E-09 19-84 / 21-84
phrog_7498 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 96.0 0.00017 15-84 / 14-93
phrog_7882 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 97.6 1.3E-07 14-84 / 28-94
phrog_8453 no annotation unknown function 98.0 6.2E-09 21-95 / 22-114
phrog_8540 replication initiation O-like DNA, RNA and nucleotide metabolism 96.9 6.6E-06 15-84 / 9-73
phrog_9088 no annotation unknown function 96.1 0.00011 25-93 / 44-114
phrog_9285 no annotation unknown function 95.8 0.00032 44-84 / 31-71
phrog_9758 no annotation unknown function 90.1 0.061 19-77 / 8-60
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.0049 48-70 / 19-41

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF06926.10 Putative replisome organiser protein C-terminus 6.2E-08 258-333 / 3-74
PF14557.5 Putative AphA-like transcriptional regulator 4.8E-06 30-124 / 4-95
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 2.3E-05 31-93 / 5-57
PF03965.15 Penicillinase repressor 2.8E-05 33-93 / 2-58
PF04492.12 Bacteriophage replication protein O 4.2E-05 29-92 / 22-83
PF02334.15 Replication terminator protein 5.2E-05 59-124 / 32-108
PF05732.10 Firmicute plasmid replication protein (RepL) 5.4E-05 24-92 / 44-109
PF07381.10 Winged helix DNA-binding domain (DUF1495) 5.5E-05 31-114 / 6-86
PF14277.5 Domain of unknown function (DUF4364) 5.7E-05 59-120 / 16-74
PF05584.10 Sulfolobus plasmid regulatory protein 6.1E-05 31-92 / 3-52
PF02002.16 TFIIE alpha subunit 0.00011 35-93 / 13-61
PF04079.15 Segregation and condensation complex subunit ScpB 0.00013 29-116 / 78-149
PF09114.9 Transcription factor MotA, activation domain 0.00013 29-120 / 11-82
PF13601.5 Winged helix DNA-binding domain 0.00017 59-116 / 15-69
PF03551.13 Transcriptional regulator PadR-like family 0.00019 59-115 / 15-71
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0002 59-92 / 24-57
PF13463.5 Winged helix DNA-binding domain 0.00023 35-92 / 4-51
PF14394.5 Domain of unknown function (DUF4423) 0.00024 59-93 / 37-73
PF11313.7 Protein of unknown function (DUF3116) 0.00025 59-118 / 21-81
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00026 32-91 / 11-60
PF16221.4 winged helix-turn-helix 0.00028 35-90 / 32-78
PF01090.18 Ribosomal protein S19e 0.00036 37-119 / 54-135
PF04358.12 DsrC like protein 0.0004 29-92 / 34-95
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00046 30-92 / 4-56
PF09639.9 YjcQ protein 0.00048 59-119 / 17-83
PF03428.12 Replication protein C N-terminal domain 0.00054 24-93 / 33-106
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00053 59-118 / 19-74
PF08784.10 Replication protein A C terminal 0.00058 30-92 / 36-95
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00067 31-93 / 9-61
PF09012.9 FeoC like transcriptional regulator 0.00068 59-94 / 15-50
PF10711.8 Hypothetical protein (DUF2513) 0.00083 59-119 / 19-85
PF05158.11 RNA polymerase Rpc34 subunit 0.00093 30-93 / 88-143
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.00093 31-119 / 2-80
PF01475.18 Ferric uptake regulator family 0.00094 31-93 / 4-62
PF01638.16 HxlR-like helix-turn-helix 0.00093 59-115 / 20-73
PF02295.16 Adenosine deaminase z-alpha domain 0.00096 59-92 / 19-53
PF08222.10 CodY helix-turn-helix domain 0.001 59-92 / 5-38
PF01726.15 LexA DNA binding domain 0.001 59-92 / 26-60
PF14947.5 Winged helix-turn-helix 0.0012 59-92 / 17-50
PF09202.10 Rio2, N-terminal 0.0016 59-92 / 25-58
PF01047.21 MarR family 0.0016 59-93 / 18-52
PF04182.11 B-block binding subunit of TFIIIC 0.0017 59-93 / 19-53
PF13412.5 Winged helix-turn-helix DNA-binding 0.002 59-88 / 18-47
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0023 59-92 / 25-58
PF12840.6 Helix-turn-helix domain 0.0026 33-92 / 7-54
PF01022.19 Bacterial regulatory protein, arsR family 0.0028 59-88 / 17-46
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.0031 59-94 / 17-54
PF09824.8 ArsR transcriptional regulator 0.0034 33-91 / 16-61
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.0036 31-92 / 5-60
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.004 30-82 / 16-75
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0045 31-93 / 5-57
PF09904.8 Winged helix-turn helix 0.0046 59-91 / 22-54
PF13034.5 Protein of unknown function (DUF3895) 0.0048 33-93 / 2-68
PF12802.6 MarR family 0.0047 59-92 / 22-55
PF07848.11 PaaX-like protein 0.0051 59-92 / 21-57
PF13730.5 Helix-turn-helix domain 0.0061 32-88 / 3-52

Annotations of the NCBI proteins of this PHROG


8:hypothetical protein 2:helix-turn-helix DNA-binding domain-containing protein 1:ankyrin repeat protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006412 translation
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0006383 transcription by RNA polymerase III
GO:0006260 DNA replication
GO:0004674 protein serine/threonine kinase activity
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding

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