phrog_8148 is made of 14 protein sequences and is annotated as "terminase small subunit"
Functional category: head and packaging


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
64.86 76 64


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX160216_p31 ANT43951.1 small subunit terminase KX160216 Lactococcus phage 98202 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_002703_p29 NP_108708.1 small sub-unit terminase NC_002703 Lactococcus phage Tuc2009 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KX160215_p32 ANT43897.1 small subunit terminase KX160215 Lactococcus phage 98104 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_031023_p2 YP_009280328.1 TerS NC_031023 Streptococcus virus 9874 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KX160217_p30 ANT44003.1 small subunit terminase KX160217 Lactococcus phage 98203 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX879642_p1 APC45823.1 terminase small subunit KX879642 Streptococcus phage CHPC926 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX160218_p34 ANT44059.1 small subunit terminase KX160218 Lactococcus phage 98204 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p380706 no NCBI prot ID no annotation VI_04539 Bacilli_gi_485065228_0_16087 Viruses.
KX160213_p31 ANT43785.1 small subunit terminase KX160213 Lactococcus phage 98102 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX160205_p36 ANT43366.1 small subunit terminase KX160205 Lactococcus phage 49801 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX160214_p34 ANT43841.1 small subunit terminase KX160214 Lactococcus phage 98103 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_029022_p36 YP_009219402.1 terminase NC_029022 Clostridium phage phiCT9441A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
KX160212_p33 ANT43732.1 small subunit terminase KX160212 Lactococcus phage 98101 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p130819 no NCBI prot ID no annotation VI_01276 Clostridia_gi_548232719 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_38 1538 terminase large subunit head and packaging 13 1.62E-32 22.91
phrog_59 1210 HNH endonuclease DNA, RNA and nucleotide metabolism 6 5.02E-15 5.42

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_30251 terminase large subunit head and packaging 99.8 6.5E-23 1-64 / 1-63
phrog_4758 terminase large subunit head and packaging 98.2 1.6E-09 2-64 / 5-79

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01637.17 ATPase domain predominantly from Archaea 2.5E-06 56-75 / 19-38
PF05673.12 Protein of unknown function (DUF815) 3.3E-06 57-75 / 54-72
PF00625.20 Guanylate kinase 3.5E-06 58-75 / 3-20
PF07931.11 Chloramphenicol phosphotransferase-like protein 3.9E-06 58-75 / 2-19
PF10443.8 RNA12 protein 4E-06 56-74 / 16-34
PF03976.13 Polyphosphate kinase 2 (PPK2) 4E-06 56-75 / 27-46
PF06414.11 Zeta toxin 5E-06 56-75 / 13-32
PF00308.17 Bacterial dnaA protein 5.2E-06 57-75 / 33-51
PF13521.5 AAA domain 6.2E-06 60-75 / 2-17
PF13173.5 AAA domain 6.3E-06 58-75 / 3-20
PF13671.5 AAA domain 7.1E-06 60-75 / 2-17
PF03266.14 NTPase 7.8E-06 60-75 / 2-17
PF13238.5 AAA domain 8.5E-06 60-75 / 1-16
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 8.7E-06 56-75 / 44-63
PF01745.15 Isopentenyl transferase 8.8E-06 58-75 / 2-19
PF07693.13 KAP family P-loop domain 1E-05 56-75 / 30-49
PF04851.14 Type III restriction enzyme, res subunit 1E-05 57-75 / 23-41
PF05729.11 NACHT domain 1.1E-05 59-75 / 2-18
PF10923.7 P-loop Domain of unknown function (DUF2791) 1.2E-05 56-75 / 48-67
PF13191.5 AAA ATPase domain 1.2E-05 58-75 / 25-42
PF03215.14 Rad17 cell cycle checkpoint protein 1.2E-05 57-75 / 45-63
PF00158.25 Sigma-54 interaction domain 1.3E-05 57-75 / 22-40
PF14516.5 AAA-like domain 1.6E-05 56-75 / 29-48
PF01712.18 Deoxynucleoside kinase 1.6E-05 60-75 / 1-16
PF01591.17 6-phosphofructo-2-kinase 1.6E-05 56-75 / 8-27
PF08433.9 Chromatin associated protein KTI12 1.6E-05 58-75 / 2-19
PF12775.6 P-loop containing dynein motor region D3 1.8E-05 57-75 / 33-51
PF05621.10 Bacterial TniB protein 2E-05 58-75 / 39-56
PF06431.10 Polyomavirus large T antigen C-terminus 2E-05 57-75 / 155-173
PF00910.21 RNA helicase 2.1E-05 61-75 / 2-16
PF08303.10 tRNA ligase kinase domain 2.1E-05 60-75 / 2-17
PF00931.21 NB-ARC domain 2.2E-05 56-75 / 19-38
PF13189.5 Cytidylate kinase-like family 2.6E-05 60-75 / 2-17
PF09820.8 Predicted AAA-ATPase 2.6E-05 57-75 / 31-49
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 2.6E-05 57-75 / 4-22
PF01121.19 Dephospho-CoA kinase 2.7E-05 59-75 / 2-18
PF13177.5 DNA polymerase III, delta subunit 2.8E-05 57-75 / 19-37
PF02223.16 Thymidylate kinase 2.8E-05 62-75 / 1-14
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 3.1E-05 59-75 / 2-18
PF00485.17 Phosphoribulokinase / Uridine kinase family 3.1E-05 60-75 / 2-17
PF01443.17 Viral (Superfamily 1) RNA helicase 3.1E-05 60-75 / 1-16
PF10236.8 Mitochondrial ribosomal death-associated protein 3 3.1E-05 56-75 / 23-42
PF10649.8 Protein of unknown function (DUF2478) 3.2E-05 61-75 / 2-16
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 3.6E-05 57-75 / 14-32
PF05272.10 Virulence-associated protein E 3.8E-05 57-75 / 59-77
PF13401.5 AAA domain 3.9E-05 57-75 / 5-23
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 4E-05 60-75 / 1-16
PF14532.5 Sigma-54 interaction domain 4.1E-05 57-75 / 21-39
PF07728.13 AAA domain (dynein-related subfamily) 4.3E-05 60-75 / 2-17
PF03969.15 AFG1-like ATPase 4.3E-05 57-75 / 67-85
PF00004.28 ATPase family associated with various cellular activities (AAA) 4.9E-05 60-75 / 1-16
PF09848.8 Uncharacterized conserved protein (DUF2075) 5.2E-05 58-75 / 2-19
PF07726.10 ATPase family associated with various cellular activities (AAA) 6.3E-05 60-75 / 2-17
PF04665.11 Poxvirus A32 protein 6.5E-05 57-75 / 13-31
PF06068.12 TIP49 C-terminus 6.7E-05 57-75 / 50-68
PF03668.14 P-loop ATPase protein family 7.1E-05 58-75 / 2-19
PF12780.6 P-loop containing dynein motor region D4 7.2E-05 57-75 / 31-49
PF05707.11 Zonular occludens toxin (Zot) 7.6E-05 59-75 / 2-18
PF02224.17 Cytidylate kinase 7.7E-05 60-75 / 1-16
PF05970.13 PIF1-like helicase 7.7E-05 56-75 / 21-40
PF00493.22 MCM2/3/5 family 8.3E-05 58-75 / 58-75
PF02562.15 PhoH-like protein 8.3E-05 58-74 / 20-36
PF00406.21 Adenylate kinase 8.4E-05 62-75 / 1-14
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 8.7E-05 57-75 / 32-50
PF00519.16 Papillomavirus helicase 9.3E-05 57-75 / 262-280
PF01078.20 Magnesium chelatase, subunit ChlI 9.6E-05 57-75 / 22-40
PF00265.17 Thymidine kinase 0.0001 59-75 / 3-19
PF13654.5 AAA domain 0.00011 56-75 / 23-42
PF01926.22 50S ribosome-binding GTPase 0.00011 60-75 / 2-17
PF04275.13 Phosphomevalonate kinase 0.00011 62-75 / 1-14
PF01695.16 IstB-like ATP binding protein 0.00012 57-75 / 48-66
PF01583.19 Adenylylsulphate kinase 0.00015 58-75 / 3-20
PF07724.13 AAA domain (Cdc48 subfamily) 0.00017 58-75 / 4-21
PF07088.10 GvpD gas vesicle protein 0.00017 56-75 / 9-28
PF01057.16 Parvovirus non-structural protein NS1 0.00018 57-75 / 118-136
PF13479.5 AAA domain 0.00019 58-75 / 3-20
PF13604.5 AAA domain 0.00021 60-75 / 19-34
PF06745.12 KaiC 0.00022 56-75 / 18-37
PF13337.5 Putative ATP-dependent Lon protease 0.00024 57-75 / 206-224
PF09439.9 Signal recognition particle receptor beta subunit 0.00024 58-75 / 4-21
PF13207.5 AAA domain 0.00026 63-75 / 1-13
PF03796.14 DnaB-like helicase C terminal domain 0.00028 57-75 / 19-37
PF13481.5 AAA domain 0.00028 57-75 / 28-46
PF07652.13 Flavivirus DEAD domain 0.00029 57-72 / 4-19
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0003 59-75 / 2-18
PF13476.5 AAA domain 0.00034 58-75 / 21-38
PF13086.5 AAA domain 0.00035 60-74 / 19-33
PF13245.5 AAA domain 0.00036 57-74 / 11-28
PF07475.11 HPr Serine kinase C-terminal domain 0.00037 57-75 / 14-32
PF10662.8 Ethanolamine utilisation - propanediol utilisation 0.00043 59-75 / 3-19
PF05127.13 Helicase 0.00045 61-75 / 1-15
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 0.00047 60-75 / 2-17
PF04670.11 Gtr1/RagA G protein conserved region 0.00049 60-75 / 2-17
PF00437.19 Type II/IV secretion system protein 0.00052 57-75 / 130-148
PF00025.20 ADP-ribosylation factor family 0.00054 57-75 / 14-32
PF00154.20 recA bacterial DNA recombination protein 0.00056 57-75 / 52-70
PF00448.21 SRP54-type protein, GTPase domain 0.00056 59-75 / 3-19
PF01580.17 FtsK/SpoIIIE family 0.00058 57-75 / 38-56
PF08423.10 Rad51 0.00058 57-75 / 37-55
PF03029.16 Conserved hypothetical ATP binding protein 0.00059 62-75 / 1-14
PF00071.21 Ras family 0.00068 60-75 / 2-17
PF04548.15 AIG1 family 0.00077 59-75 / 2-18
PF02421.17 Ferrous iron transport protein B 0.00085 60-75 / 2-17
PF08298.10 PrkA AAA domain 0.00093 57-75 / 85-103
PF00735.17 Septin 0.00095 58-75 / 5-22
PF06309.10 Torsin 0.001 58-75 / 53-70
PF10412.8 Type IV secretion-system coupling protein DNA-binding domain 0.0011 57-74 / 15-32
PF07999.10 Retrotransposon hot spot protein 0.0011 57-74 / 126-143
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.0011 57-75 / 122-140
PF01935.16 Domain of unknown function DUF87 0.0013 57-75 / 25-43
PF12846.6 AAA-like domain 0.0015 57-74 / 21-38
PF11111.7 Centromere protein M (CENP-M) 0.0016 57-75 / 15-33
PF00350.22 Dynamin family 0.0016 61-75 / 2-16
PF00580.20 UvrD/REP helicase N-terminal domain 0.0017 58-74 / 14-30
PF00488.20 MutS domain V 0.0018 61-75 / 2-16
PF06048.10 Domain of unknown function (DUF927) 0.0022 57-75 / 188-206
PF05872.11 Bacterial protein of unknown function (DUF853) 0.0023 57-75 / 21-39
PF05049.12 Interferon-inducible GTPase (IIGP) 0.0024 57-75 / 35-53
PF02456.14 Adenovirus IVa2 protein 0.0024 59-75 / 82-98
PF16813.4 CRISPR-associated protein Csn2 subfamily St 0.0026 57-75 / 15-33
PF00693.17 Thymidine kinase from herpesvirus 0.0028 64-75 / 1-12
PF12631.6 MnmE helical domain 0.0028 58-75 / 95-112
PF00009.26 Elongation factor Tu GTP binding domain 0.0028 58-75 / 4-21
PF02263.18 Guanylate-binding protein, N-terminal domain 0.003 56-75 / 20-39
PF00503.19 G-protein alpha subunit 0.0031 58-75 / 22-39
PF08477.12 Ras of Complex, Roc, domain of DAPkinase 0.0035 60-75 / 2-17
PF03308.15 ArgK protein 0.0036 57-75 / 29-47
PF03193.15 RsgA GTPase 0.0037 58-75 / 107-124
PF09547.9 Stage IV sporulation protein A (spore_IV_A) 0.0038 57-75 / 17-35
PF04310.11 MukB N-terminal 0.0039 58-75 / 27-44
PF13175.5 AAA ATPase domain 0.0043 59-75 / 24-40
PF13166.5 AAA domain 0.0044 56-75 / 17-36
PF04317.11 YcjX-like family, DUF463 0.0048 59-75 / 2-18
PF02534.13 Type IV secretory system Conjugative DNA transfer 0.0052 57-74 / 43-60
PF03205.13 Molybdopterin guanine dinucleotide synthesis protein B 0.0054 60-75 / 2-17
PF04466.12 Phage terminase large subunit 0.0055 59-74 / 3-18
PF01293.19 Phosphoenolpyruvate carboxykinase 0.0055 58-74 / 206-222
PF16575.4 mRNA cleavage and polyadenylation factor CLP1 P-loop 0.0058 64-75 / 1-12
PF16260.4 Domain of unknown function (DUF4914) 0.0061 57-75 / 240-258
PF00270.28 DEAD/DEAH box helicase 0.0068 58-74 / 15-31
PF05783.10 Dynein light intermediate chain (DLIC) 0.0073 58-75 / 26-43
PF08283.10 Geminivirus rep protein central domain 0.0077 56-72 / 89-105
PF02689.13 Helicase 0.0076 57-75 / 53-71
PF13514.5 AAA domain 0.0089 58-75 / 27-44

Annotations of the NCBI proteins of this PHROG


8:small subunit terminase 1:small sub-unit terminase 1:TerS 1:terminase small subunit 1:terminase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005737 cytoplasm
GO:0015937 coenzyme A biosynthetic process
GO:0016740 transferase activity
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0004140 dephospho-CoA kinase activity
GO:0006576 cellular biogenic amine metabolic process
GO:0008134 transcription factor binding
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0004127 cytidylate kinase activity
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003873 6-phosphofructo-2-kinase activity
GO:0006695 cholesterol biosynthetic process
GO:0004161 dimethylallyltranstransferase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0008152 metabolic process
GO:0016301 kinase activity
GO:0006109 regulation of carbohydrate metabolic process
GO:0006298 mismatch repair
GO:0004003 ATP-dependent DNA helicase activity
GO:0030983 mismatched DNA binding
GO:0003924 GTPase activity
GO:0005524 ATP binding
GO:0006094 gluconeogenesis
GO:0043934 sporulation
GO:0004672 protein kinase activity
GO:0007186 G-protein coupled receptor signaling pathway
GO:0009058 biosynthetic process
GO:0009295 nucleoid
GO:0019079 viral genome replication
GO:0008026 ATP-dependent helicase activity
GO:0004631 phosphomevalonate kinase activity
GO:0003676 nucleic acid binding
GO:0006355 regulation of transcription, DNA-templated
GO:0006000 fructose metabolic process
GO:0000166 nucleotide binding
GO:0006270 DNA replication initiation
GO:0016887 ATPase activity
GO:0009236 cobalamin biosynthetic process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0043531 ADP binding
GO:0007059 chromosome segregation
GO:0006139 nucleobase-containing compound metabolic process
GO:0016020 membrane
GO:0003724 RNA helicase activity
GO:0019072 viral genome packaging
GO:0051188 cofactor biosynthetic process
GO:0019001 guanyl nucleotide binding
GO:0016787 hydrolase activity
GO:0009378 four-way junction helicase activity
GO:0004673 protein histidine kinase activity
GO:0003972 RNA ligase (ATP) activity
GO:0000723 telomere maintenance
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0019073 viral DNA genome packaging
GO:0003723 RNA binding
GO:0006281 DNA repair
GO:0003697 single-stranded DNA binding
GO:0030261 chromosome condensation
GO:0006230 TMP biosynthetic process
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0009291 unidirectional conjugation
GO:0004386 helicase activity
GO:0000155 phosphorelay sensor kinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0004797 thymidine kinase activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0005525 GTP binding

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