phrog_8540 is made of 13 protein sequences and is annotated as "replication initiation O-like"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
210.62 228 222


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KU160658_p23 ALY09778.1 HTH DNA binding domain protein KU160658 Arthrobacter phage Muttlie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
MF140409_p23 ASR83530.1 HTH DNA binding domain protein MF140409 Arthrobacter phage Elkhorn Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
KT355475_p23 ALF00867.1 hypothetical protein KT355475 Arthrobacter phage Sandman Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
NC_028692_p23 YP_009191316.1 helix-turn-helix DNA binding domain protein NC_028692 Arthrobacter phage Decurro Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus.
KT355473_p23 ALF00779.1 helix-turn-helix DNA binding domain protein KT355473 Arthrobacter phage Jessica Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
MF140429_p23 ASR84003.1 HTH DNA binding protein MF140429 Arthrobacter phage Swenson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
MF140415_p24 ASR83556.1 HTH DNA binding domain protein MF140415 Arthrobacter phage KylieMac Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
MF140417_p23 ASR83583.1 HTH DNA binding protein MF140417 Arthrobacter phage Link Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
KU160670_p22 ALY10662.1 HTH DNA binding domain protein KU160670 Arthrobacter phage Toulouse Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
MF140431_p23 ASM62391.1 HTH DNA-binding protein MF140431 Arthrobacter phage Taj14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Decurrovirus; unclassified Decurrovirus.
p76370 no NCBI prot ID no annotation VI_09148 Gammaproteobacteria_gi_421683688 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p174806 no NCBI prot ID no annotation VI_02637 Gammaproteobacteria_gi_354697327_944224_982829 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterobacterial phage mEp213.
p287601 no NCBI prot ID no annotation VI_06418 Gammaproteobacteria_gi_145631693 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_10694 10 no annotation unknown function 10 0 1000
phrog_66 1138 excisionase and transcriptional regulator integration and excision 10 9.56E-26 16.14

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1032 replication initiation protein DNA, RNA and nucleotide metabolism 99.7 2.7E-22 1-79 / 1-81
phrog_11896 primosomal protein DNA, RNA and nucleotide metabolism 99.0 2E-13 1-98 / 1-97
phrog_12720 DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.017 23-76 / 35-94
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 94.5 0.0029 36-97 / 11-68
phrog_1835 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.5 0.00058 21-92 / 53-123
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 95.4 0.00076 15-78 / 24-92
phrog_21868 no annotation unknown function 95.2 0.001 3-69 / 24-93
phrog_26369 replication initiation protein DNA, RNA and nucleotide metabolism 96.0 0.00018 23-144 / 65-198
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 99.2 9.1E-15 5-98 / 8-95
phrog_345 replication initiation O-like DNA, RNA and nucleotide metabolism 97.2 1.2E-06 2-78 / 33-114
phrog_3502 no annotation unknown function 93.2 0.011 31-72 / 20-62
phrog_36008 no annotation unknown function 94.0 0.0052 33-78 / 59-104
phrog_391 replication initiation O-like DNA, RNA and nucleotide metabolism 99.9 4.7E-27 1-150 / 1-151
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 97.2 1.5E-06 29-95 / 41-101
phrog_4617 replication initiation protein DNA, RNA and nucleotide metabolism 99.8 9.1E-24 3-94 / 2-97
phrog_6643 replication initiation protein DNA, RNA and nucleotide metabolism 97.6 1E-07 1-133 / 1-133
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 97.9 2.1E-08 34-96 / 45-103
phrog_8102 replication initiation protein DNA, RNA and nucleotide metabolism 97.5 2.1E-07 9-73 / 15-84

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 3.6E-06 12-71 / 22-83
PF06970.10 Replication initiator protein A (RepA) N-terminus 9.3E-06 13-61 / 16-75
PF16221.4 winged helix-turn-helix 1.4E-05 18-69 / 32-78
PF04358.12 DsrC like protein 1.5E-05 12-71 / 34-95
PF05732.10 Firmicute plasmid replication protein (RepL) 1.9E-05 13-71 / 50-109
PF02319.19 E2F/DP family winged-helix DNA-binding domain 2.5E-05 38-71 / 24-57
PF03428.12 Replication protein C N-terminal domain 2.8E-05 7-72 / 33-106
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 4.5E-05 15-71 / 6-56
PF01726.15 LexA DNA binding domain 5E-05 38-71 / 26-60
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 6.8E-05 15-70 / 11-60
PF09012.9 FeoC like transcriptional regulator 9.3E-05 38-73 / 15-50
PF13730.5 Helix-turn-helix domain 9.8E-05 15-67 / 3-52
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0001 13-71 / 4-56
PF08784.10 Replication protein A C terminal 0.00014 15-71 / 38-95
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00015 14-71 / 6-68
PF05584.10 Sulfolobus plasmid regulatory protein 0.00016 38-71 / 19-52
PF03965.15 Penicillinase repressor 0.00018 17-72 / 3-58
PF09114.9 Transcription factor MotA, activation domain 0.00019 13-71 / 12-65
PF03551.13 Transcriptional regulator PadR-like family 0.0002 38-72 / 15-51
PF12802.6 MarR family 0.00022 38-71 / 22-55
PF14557.5 Putative AphA-like transcriptional regulator 0.00027 13-72 / 4-68
PF02295.16 Adenosine deaminase z-alpha domain 0.00029 38-71 / 19-53
PF04079.15 Segregation and condensation complex subunit ScpB 0.00031 12-73 / 78-130
PF14394.5 Domain of unknown function (DUF4423) 0.00035 38-71 / 37-72
PF08222.10 CodY helix-turn-helix domain 0.00035 38-71 / 5-38
PF13463.5 Winged helix DNA-binding domain 0.00037 38-71 / 18-51
PF01047.21 MarR family 0.00039 38-71 / 18-51
PF01475.18 Ferric uptake regulator family 0.0004 14-72 / 4-62
PF04182.11 B-block binding subunit of TFIIIC 0.00042 38-72 / 19-53
PF11313.7 Protein of unknown function (DUF3116) 0.00043 46-73 / 36-63
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00045 38-72 / 27-61
PF01090.18 Ribosomal protein S19e 0.00056 38-72 / 66-115
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00057 38-71 / 25-58
PF13601.5 Winged helix DNA-binding domain 0.00061 38-72 / 15-49
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00064 38-72 / 17-53
PF02002.16 TFIIE alpha subunit 0.00065 18-72 / 13-61
PF15977.4 Winged helix-turn-helix DNA binding 0.00073 36-70 / 22-56
PF14277.5 Domain of unknown function (DUF4364) 0.00074 38-70 / 16-52
PF13412.5 Winged helix-turn-helix DNA-binding 0.00082 38-67 / 18-47
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.00091 15-73 / 6-58
PF13545.5 Crp-like helix-turn-helix domain 0.00093 37-69 / 27-59
PF09824.8 ArsR transcriptional regulator 0.00095 16-70 / 16-61
PF05158.11 RNA polymerase Rpc34 subunit 0.001 14-72 / 89-143
PF09339.9 IclR helix-turn-helix domain 0.0011 38-69 / 19-50
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0011 38-71 / 19-52
PF01022.19 Bacterial regulatory protein, arsR family 0.0011 38-67 / 17-46
PF14502.5 Helix-turn-helix domain 0.0012 37-71 / 6-40
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.0012 14-71 / 5-60
PF02082.19 Transcriptional regulator 0.0012 38-70 / 25-57
PF09202.10 Rio2, N-terminal 0.0013 16-71 / 5-58
PF09639.9 YjcQ protein 0.0016 38-72 / 17-53
PF09904.8 Winged helix-turn helix 0.0017 38-70 / 22-54
PF14947.5 Winged helix-turn-helix 0.0017 38-71 / 17-50
PF05331.10 Protein of unknown function (DUF742) 0.0018 38-71 / 54-87
PF12840.6 Helix-turn-helix domain 0.0018 38-71 / 24-54
PF13034.5 Protein of unknown function (DUF3895) 0.002 48-72 / 40-68
PF02334.15 Replication terminator protein 0.002 49-72 / 52-75
PF07848.11 PaaX-like protein 0.0021 38-71 / 21-57
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0024 38-70 / 18-50
PF00392.20 Bacterial regulatory proteins, gntR family 0.0024 39-71 / 26-58
PF10711.8 Hypothetical protein (DUF2513) 0.0031 38-72 / 19-57
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0032 38-70 / 22-54
PF06969.15 HemN C-terminal domain 0.0036 38-70 / 21-54
PF01638.16 HxlR-like helix-turn-helix 0.0041 38-72 / 20-55
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.0043 15-71 / 3-63
PF00325.19 Bacterial regulatory proteins, crp family 0.0046 38-67 / 3-32
PF09182.9 Bacterial purine repressor, N-terminal 0.0047 38-70 / 21-58
PF01418.16 Helix-turn-helix domain, rpiR family 0.0047 14-71 / 13-68
PF08220.11 DeoR-like helix-turn-helix domain 0.005 38-70 / 15-47
PF04703.11 FaeA-like protein 0.0062 38-71 / 15-48
PF08461.9 Ribonuclease R winged-helix domain 0.0063 38-70 / 13-50
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 0.0066 38-70 / 54-86
PF17443.1 Uncharacterized protein pXO2-72 0.0068 37-70 / 8-50
PF03297.14 S25 ribosomal protein 0.0072 38-70 / 57-89
PF01316.20 Arginine repressor, DNA binding domain 0.008 38-71 / 20-55

Annotations of the NCBI proteins of this PHROG


4:HTH DNA binding domain protein 2:HTH DNA binding protein 2:helix-turn-helix DNA binding domain protein 1:HTH DNA-binding protein 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0006468 protein phosphorylation
GO:0003700 DNA binding transcription factor activity
GO:0006274 DNA replication termination
GO:0005840 ribosome
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0004674 protein serine/threonine kinase activity
GO:0009289 pilus
GO:0006383 transcription by RNA polymerase III
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0009378 four-way junction helicase activity
GO:0007131 reciprocal meiotic recombination
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0003735 structural constituent of ribosome
GO:0003723 RNA binding
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated

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