phrog_8828 is made of 12 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
112.08 281 136


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p290869 no NCBI prot ID no annotation VI_00017 Actinobacteria_gi_545352115_20076_47096 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KX620750_p61 AOT24412.1 HNH endonuclease KX620750 Propionibacterium phage B22 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Doucettevirus; Propionibacterium virus B22.
KX620754_p69 AOT24658.1 HNH endonuclease KX620754 Propionibacterium phage G4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Doucettevirus; Propionibacterium virus G4.
KX620753_p60 AOT24588.1 HNH endonuclease KX620753 Propionibacterium phage E6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Doucettevirus; Propionibacterium virus E6.
KX620751_p61 AOT24474.1 HNH endonuclease KX620751 Propionibacterium phage Doucette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Doucettevirus; Propionibacterium virus Doucette.
p202812 no NCBI prot ID no annotation VI_11983 Gammaproteobacteria_gi_565901485_0_36402 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Pseudomonas phage vB_PaeP_Tr60_Ab31.
MF360958_p346 ASV44361.1 hypothetical protein MF360958 Salicola phage SCTP-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
KF005318_p75 AGM47013.1 hypothetical protein KF005318 Alteromonas phage vB_AmaP_AD45-P3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
NC_021532_p79 YP_008126050.1 hypothetical protein NC_021532 Alteromonas phage vB_AmaP_AD45-P1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
KF005319_p74 AGM47129.1 hypothetical protein KF005319 Alteromonas phage vB_AmaP_AD45-P4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p353403 no NCBI prot ID no annotation VI_03994 Halobacteria_gi_482989397_13759_33075 Viruses.
p93766 no NCBI prot ID no annotation VI_01744 Gammaproteobacteria_gi_545284387_274566_320373 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_20395 4 no annotation unknown function 4 0 1000
phrog_19342 4 no annotation unknown function 3 4.99E-20 10.42
phrog_23483 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13172 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.4 0.056 47-57 / 1-11
phrog_1474 unknown function unknown function 90.3 0.057 2-62 / 46-103
phrog_4005 no annotation unknown function 93.1 0.012 19-67 / 22-73

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00872.17 Transposase, Mutator family 2.5E-09 42-250 / 43-235
PF09862.8 Protein of unknown function (DUF2089) 3E-08 46-133 / 1-75
PF03050.13 Transposase IS66 family 5.8E-08 91-250 / 4-139
PF12762.6 ISXO2-like transposase domain 6.6E-08 151-263 / 3-95
PF06782.10 Uncharacterised protein family (UPF0236) 1.3E-07 65-164 / 89-199
PF12760.6 Transposase zinc-ribbon domain 3.4E-06 28-76 / 4-46
PF03811.12 InsA N-terminal domain 6.6E-06 42-75 / 4-35
PF03400.12 IS1 transposase 2.7E-05 197-251 / 21-73
PF08274.11 PhnA Zinc-Ribbon 5.6E-05 44-78 / 3-29
PF07754.10 Domain of unknown function (DUF1610) 0.00014 46-75 / 1-23
PF14803.5 Nudix N-terminal 0.00017 45-77 / 2-31
PF08792.9 A2L zinc ribbon domain 0.00019 43-78 / 3-31
PF14205.5 Cysteine-rich KTR 0.00025 43-80 / 3-39
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00028 107-129 / 82-104
PF09538.9 Protein of unknown function (FYDLN_acid) 0.00029 42-80 / 8-38
PF04606.11 Ogr/Delta-like zinc finger 0.00031 45-79 / 1-38
PF14690.5 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 0.00048 43-53 / 2-12
PF03966.15 Trm112p-like protein 0.0006 42-80 / 6-37
PF09297.10 NADH pyrophosphatase zinc ribbon domain 0.00066 43-77 / 3-30
PF13453.5 Transcription factor zinc-finger 0.00074 45-78 / 1-29
PF08271.11 TFIIB zinc-binding 0.00099 45-79 / 2-30
PF09151.9 Domain of unknown function (DUF1936) 0.0014 45-76 / 1-32
PF01096.17 Transcription factor S-II (TFIIS) 0.0024 45-78 / 2-36
PF06044.11 Dam-replacing family 0.0024 34-80 / 22-65
PF02701.14 Dof domain, zinc finger 0.0052 43-79 / 3-39
PF01780.18 Ribosomal L37ae protein family 0.008 42-80 / 32-63

Annotations of the NCBI proteins of this PHROG


4:HNH endonuclease 4:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0016787 hydrolase activity
GO:0006355 regulation of transcription, DNA-templated
GO:0006412 translation
GO:0005622 intracellular
GO:0046872 metal ion binding
GO:0003735 structural constituent of ribosome
GO:0006351 transcription, DNA-templated
GO:0003676 nucleic acid binding
GO:0005840 ribosome
GO:0006313 transposition, DNA-mediated
GO:0003677 DNA binding
GO:0008270 zinc ion binding
GO:0004803 transposase activity

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