phrog_8841 is made of 12 protein sequences and is annotated as "DNA primase/helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
685.75 1020 646


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p25562 no NCBI prot ID no annotation VI_01160 Clostridia_gi_211596895_66269_137690 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p110550 no NCBI prot ID no annotation VI_01281 Clostridia_gi_160878162_3615270_3659755 Viruses.
p49736 no NCBI prot ID no annotation VI_01193 Clostridia_gi_336423913 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p117854 no NCBI prot ID no annotation VI_01215 Clostridia_gi_546486044_95813_139509 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p37525 no NCBI prot ID no annotation VI_00696 Bacilli_gi_507028124_1766_63644 Viruses.
p376255 no NCBI prot ID no annotation VI_05477 Bacilli_gi_493972587 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p27217 no NCBI prot ID no annotation VI_04769 Bacilli_gi_418917818_126423_196354 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p375984 no NCBI prot ID no annotation VI_04743 Bacilli_gi_418871954 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA phages; Staphylococcus phage PT1028.
NC_007045_p15 YP_239453.1 ORF001 NC_007045 Staphylococcus phage PT1028 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA phages.
MG711462_p22 AUV56439.1 primase/helicase MG711462 Faecalibacterium phage FP_Epona Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Eponavirus; Faecalibacterium virus Epona.
NC_018264_p43 YP_006546312.1 protein of unknown function DUF927 NC_018264 Thermoanaerobacterium phage THSA-485A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p149130 no NCBI prot ID no annotation VI_00027 Actinobacteria_gi_410685546 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_11992 8 no annotation unknown function 4 3.00E-22 12.64
phrog_695 204 DNA polymerase/primase DNA, RNA and nucleotide metabolism 4 1.50E-14 4.95
phrog_7134 16 no annotation unknown function 2 7.10E-12 2.27

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1139 DNA primase DNA, RNA and nucleotide metabolism 99.5 8.2E-19 125-580 / 376-867
phrog_25314 no annotation unknown function 99.9 1.4E-27 86-571 / 421-953

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01807.19 CHC2 zinc finger 7.1E-11 5-90 / 6-90
PF04735.11 Baculovirus DNA helicase 6.5E-10 462-630 / 862-1032
PF06048.10 Domain of unknown function (DUF927) 1.1E-09 336-561 / 18-254
PF05272.10 Virulence-associated protein E 7.5E-09 465-629 / 11-178
PF12965.6 Domain of unknown function (DUF3854) 1.2E-06 183-250 / 9-82
PF00519.16 Papillomavirus helicase 7.9E-06 503-630 / 265-384
PF01057.16 Parvovirus non-structural protein NS1 2.6E-05 503-630 / 121-245
PF13155.5 Toprim-like 2.9E-05 187-253 / 1-58
PF13362.5 Toprim domain 3.7E-05 185-240 / 1-51
PF00910.21 RNA helicase 0.00017 504-525 / 2-23
PF06431.10 Polyomavirus large T antigen C-terminus 0.00021 503-561 / 158-214
PF13662.5 Toprim domain 0.00032 185-253 / 2-75
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0011 503-561 / 35-96
PF01078.20 Magnesium chelatase, subunit ChlI 0.0019 503-525 / 25-47
PF00493.22 MCM2/3/5 family 0.0025 503-526 / 60-83
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.0045 503-525 / 48-70
PF01751.21 Toprim domain 0.0045 186-201 / 2-17
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0049 503-526 / 4-27
PF08298.10 PrkA AAA domain 0.0063 503-525 / 88-110
PF13671.5 AAA domain 0.0072 503-525 / 2-24
PF13521.5 AAA domain 0.0074 503-526 / 2-25
PF00625.20 Guanylate kinase 0.0076 503-525 / 5-27
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.0077 502-526 / 30-54
PF13238.5 AAA domain 0.0085 503-526 / 1-24

Annotations of the NCBI proteins of this PHROG


1:protein of unknown function DUF927 1:protein of an unannotated phage 1:primase/helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003724 RNA helicase activity
GO:0008270 zinc ion binding
GO:0003896 DNA primase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0006270 DNA replication initiation
GO:0005524 ATP binding
GO:0019079 viral genome replication
GO:0006281 DNA repair
GO:0016740 transferase activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0006260 DNA replication
GO:0009378 four-way junction helicase activity

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