phrog_9172 is made of 12 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
499.92 609 514


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX607102_p48 AON96530.1 archaeal AAA-ATPase KX607102 Acidianus two-tailed virus variant 1 Viruses; Bicaudaviridae; Bicaudavirus; unclassified Bicaudavirus.
NC_023585_p18 YP_009008085.1 conserved archaeal viral AAA-ATPase NC_023585 Sulfolobus monocaudavirus SMV1 Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
NC_029020_p18 YP_009219233.1 hypothetical protein NC_029020 Sulfolobus monocaudavirus SMV2 Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
NC_020077_p48 YP_007348292.1 putative ATPase NC_020077 Sulfolobus virus STSV2 Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
KX607101_p47 AON96466.1 archaeal AAA-ATPase KX607101 Acidianus two-tailed virus 2 Viruses; Bicaudaviridae; Bicaudavirus; unclassified Bicaudavirus.
NC_029103_p24 YP_009226247.1 putative cell division control protein NC_029103 Sulfolobus monocaudavirus SMV3 Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
NC_007409_p53 YP_319884.1 hypothetical protein NC_007409 Acidianus two-tailed virus Viruses; Bicaudaviridae; Bicaudavirus.
NC_029316_p56 YP_009230309.1 AAA+ ATPase NC_029316 Acidianus tailed spindle virus Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
NC_029011_p20 YP_009218484.1 putative cell division control protein NC_029011 Sulfolobus monocaudavirus SMV4 Viruses; Bicaudaviridae; unclassified Bicaudaviridae.
NC_028992_p14 YP_009216720.1 putative Cell division protein FtsH NC_028992 Sulfolobales Virus YNP2 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
NC_029027_p16 YP_009219915.1 putative Cell division protein FtsH NC_029027 Sulfolobales virus YNP1 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
NC_014321_p4 YP_003773387.1 AAA-ATPase, CDC48-type NC_014321 Hyperthermophilic Archaeal Virus 2 Viruses; unclassified viruses; unclassified archaeal viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_21977 4 no annotation unknown function 3 2.19E-19 9.78
phrog_24487 3 no annotation unknown function 3 0 1000
phrog_23657 3 no annotation unknown function 3 0 1000
phrog_27360 3 no annotation unknown function 2 1.09E-14 5.08
phrog_23662 3 no annotation unknown function 2 1.09E-14 5.08

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10255 kinase other 92.6 0.018 99-129 / 3-33
phrog_10401 ATPase other 95.8 0.00031 96-417 / 11-306
phrog_10440 no annotation unknown function 97.3 8.8E-07 70-255 / 197-372
phrog_11143 no annotation unknown function 92.5 0.019 96-167 / 45-144
phrog_1156 DNA primase DNA, RNA and nucleotide metabolism 96.0 0.00019 97-235 / 515-649
phrog_11838 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 97.7 6.6E-08 96-218 / 39-143
phrog_11907 ATPase other 96.6 2E-05 96-252 / 170-345
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 96.2 0.00011 96-219 / 13-148
phrog_1250 unknown function unknown function 91.8 0.029 74-236 / 70-248
phrog_1297 ATPase other 94.1 0.0047 97-228 / 25-164
phrog_139 deoxynucleoside monophosphate kinase other 91.9 0.027 99-124 / 4-29
phrog_14322 no annotation unknown function 98.3 7.5E-10 100-265 / 197-347
phrog_15585 no annotation unknown function 95.7 0.00036 81-237 / 326-492
phrog_16448 ATPase other 96.7 1.5E-05 78-240 / 9-168
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 99.1 3.6E-14 68-284 / 14-203
phrog_170 PhoH-like phosphate starvation-inducible other 90.0 0.064 97-130 / 50-90
phrog_1815 guanylate kinase other 95.6 0.00044 100-247 / 5-134
phrog_1829 DNA primase DNA, RNA and nucleotide metabolism 93.1 0.012 82-228 / 486-624
phrog_19600 ATPase other 94.6 0.0026 81-247 / 69-235
phrog_1979 no annotation unknown function 90.5 0.053 96-234 / 124-271
phrog_197 Zot-like toxin moron, auxiliary metabolic gene and host takeover 94.8 0.002 101-236 / 5-145
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 90.2 0.061 87-129 / 185-232
phrog_2071 ATPase other 95.7 0.00038 100-135 / 6-39
phrog_2107 thymidylate kinase other 95.8 0.00031 99-137 / 5-47
phrog_21479 no annotation unknown function 92.2 0.022 101-129 / 30-58
phrog_22963 no annotation unknown function 92.4 0.02 86-115 / 22-53
phrog_2376 ATPase other 97.8 3.6E-08 74-247 / 47-204
phrog_2392 ABC transporter moron, auxiliary metabolic gene and host takeover 90.3 0.058 78-158 / 357-442
phrog_249 porphyrin biosynthesis moron, auxiliary metabolic gene and host takeover 96.2 9.2E-05 11-247 / 16-268
phrog_25411 no annotation unknown function 92.2 0.022 97-215 / 230-342
phrog_2666 terminase large subunit head and packaging 91.0 0.042 146-256 / 103-197
phrog_27475 no annotation unknown function 93.1 0.012 96-223 / 441-554
phrog_29395 no annotation unknown function 95.5 0.0006 73-229 / 114-281
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 94.1 0.0048 98-123 / 39-64
phrog_29662 ATP-dependent protease other 95.9 0.00023 70-244 / 315-481
phrog_296 DNA transposition protein integration and excision 96.9 5.7E-06 97-247 / 91-239
phrog_30773 no annotation unknown function 99.2 7E-15 80-289 / 150-359
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 95.5 0.00063 96-167 / 24-119
phrog_33861 no annotation unknown function 94.4 0.0036 201-235 / 318-354
phrog_35110 no annotation unknown function 97.3 1E-06 83-231 / 220-399
phrog_3757 no annotation unknown function 99.9 4.9E-29 69-287 / 91-301
phrog_4210 DNA polymerase DNA, RNA and nucleotide metabolism 94.2 0.0044 96-227 / 172-291
phrog_4339 no annotation unknown function 97.2 1.5E-06 158-263 / 314-431
phrog_4871 ATP-dependent protease other 96.6 1.9E-05 90-306 / 475-709
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 98.2 1.4E-09 77-229 / 93-235
phrog_5484 DnaA-like replication initiation protein DNA, RNA and nucleotide metabolism 95.2 0.001 95-175 / 25-110
phrog_5534 no annotation unknown function 96.0 0.00015 92-247 / 22-200
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 98.7 6.2E-12 81-284 / 22-200
phrog_6891 ATPase other 94.4 0.0037 96-215 / 33-151
phrog_6931 no annotation unknown function 93.4 0.0099 99-139 / 189-222
phrog_7485 no annotation unknown function 99.0 3.7E-13 75-250 / 197-376
phrog_761 thymidylate kinase other 93.3 0.011 99-124 / 4-29
phrog_7998 no annotation unknown function 96.1 0.00012 97-170 / 38-128
phrog_8638 no annotation unknown function 99.1 5.8E-14 96-285 / 312-494

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00308.17 Bacterial dnaA protein 2.3E-08 321-505 / 7-216
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 2E-07 320-409 / 17-112
PF05673.12 Protein of unknown function (DUF815) 1.1E-07 83-134 / 28-78
PF06068.12 TIP49 C-terminus 1.9E-07 320-370 / 22-74
PF07693.13 KAP family P-loop domain 9E-07 242-302 / 242-303
PF05621.10 Bacterial TniB protein 6.2E-07 111-134 / 39-62
PF13654.5 AAA domain 0.00095 322-371 / 2-49
PF14532.5 Sigma-54 interaction domain 0.00045 110-134 / 21-45
PF00158.25 Sigma-54 interaction domain 2.8E-05 110-135 / 22-47
PF09820.8 Predicted AAA-ATPase 6.8E-06 321-370 / 14-55
PF01637.17 ATPase domain predominantly from Archaea 3.5E-06 86-134 / 1-44
PF06431.10 Polyomavirus large T antigen C-terminus 2.3E-05 345-407 / 154-216
PF12775.6 P-loop containing dynein motor region D3 1.8E-05 109-135 / 32-58
PF10923.7 P-loop Domain of unknown function (DUF2791) 0.00027 320-370 / 23-73
PF14516.5 AAA-like domain 1.4E-05 321-370 / 9-54
PF13191.5 AAA ATPase domain 0.0011 86-134 / 2-48
PF03215.14 Rad17 cell cycle checkpoint protein 2.1E-05 321-371 / 18-70
PF13173.5 AAA domain 1E-05 346-369 / 2-25
PF13337.5 Putative ATP-dependent Lon protease 0.0032 109-135 / 205-231
PF10443.8 RNA12 protein 1.3E-05 328-369 / 2-41
PF01078.20 Magnesium chelatase, subunit ChlI 4.1E-05 323-370 / 4-46
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.0001 349-371 / 1-23
PF05729.11 NACHT domain 5.8E-05 112-134 / 2-24
PF03969.15 AFG1-like ATPase 7.2E-05 109-135 / 66-92
PF13177.5 DNA polymerase III, delta subunit 2.8E-05 328-370 / 3-43
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 2E-05 329-409 / 16-100
PF00931.21 NB-ARC domain 2.4E-05 328-370 / 2-44
PF04851.14 Type III restriction enzyme, res subunit 3.5E-05 345-370 / 22-47
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.00017 113-137 / 2-26
PF03266.14 NTPase 0.00026 113-134 / 2-23
PF13401.5 AAA domain 0.00012 346-370 / 5-29
PF04665.11 Poxvirus A32 protein 0.00031 109-134 / 12-37
PF07728.13 AAA domain (dynein-related subfamily) 0.00032 113-137 / 2-26
PF12780.6 P-loop containing dynein motor region D4 0.00045 109-142 / 30-63
PF00493.22 MCM2/3/5 family 0.00037 110-136 / 57-83
PF00519.16 Papillomavirus helicase 0.00045 345-406 / 261-320
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.0006 113-139 / 1-27
PF07724.13 AAA domain (Cdc48 subfamily) 0.0021 111-134 / 4-27
PF00910.21 RNA helicase 0.0043 113-135 / 1-23
PF01695.16 IstB-like ATP binding protein 0.00033 345-370 / 47-72
PF08298.10 PrkA AAA domain 0.00041 85-134 / 59-109
PF05272.10 Virulence-associated protein E 0.00072 346-407 / 59-117
PF06144.12 DNA polymerase III, delta subunit 0.00046 113-297 / 1-176
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.0053 348-370 / 2-24
PF00265.17 Thymidine kinase 0.00057 347-370 / 2-25
PF07652.13 Flavivirus DEAD domain 0.00065 346-367 / 4-26
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0023 112-137 / 3-28
PF13245.5 AAA domain 0.0012 346-370 / 11-35
PF00625.20 Guanylate kinase 0.0031 111-135 / 3-27
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.0013 347-370 / 2-25
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.0044 109-135 / 27-53
PF13671.5 AAA domain 0.005 113-135 / 2-24
PF06414.11 Zeta toxin 0.0044 109-135 / 13-39
PF13521.5 AAA domain 0.0048 113-135 / 2-24
PF05127.13 Helicase 0.0027 350-370 / 1-21
PF01745.15 Isopentenyl transferase 0.0046 111-136 / 2-27
PF10649.8 Protein of unknown function (DUF2478) 0.0059 113-135 / 1-23
PF05970.13 PIF1-like helicase 0.0032 345-370 / 21-46
PF13238.5 AAA domain 0.0059 113-135 / 1-23
PF13189.5 Cytidylate kinase-like family 0.0084 113-136 / 2-25
PF08303.10 tRNA ligase kinase domain 0.0041 348-371 / 1-24
PF01121.19 Dephospho-CoA kinase 0.0083 112-137 / 2-27
PF01591.17 6-phosphofructo-2-kinase 0.0046 346-371 / 9-34
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.0047 346-370 / 4-28
PF01712.18 Deoxynucleoside kinase 0.0047 349-371 / 1-23
PF08433.9 Chromatin associated protein KTI12 0.0049 347-371 / 2-26
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0055 348-371 / 1-24
PF02224.17 Cytidylate kinase 0.0071 349-372 / 1-24
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.0082 345-370 / 13-38
PF02223.16 Thymidylate kinase 0.0082 351-371 / 1-21

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 2:Cell division protein FtsH 2:archaeal AAA-ATPase 1:AAA+ ATPase 1:conserved archaeal viral AAA-ATPase 1:AAA-ATPase, CDC48-type 1:protein of an unannotated phage 1:ATPase 1:cell division control protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K14575 AFG2, DRG1, SPATA5 : AAA family ATPase ko03008 Ribosome biogenesis in eukaryotes 85 1
K13525 VCP, CDC48 : transitional endoplasmic reticulum ATPase ko04141 Protein processing in endoplasmic reticulum
ko05134 Legionellosis
79 1
K12196 VPS4 : vacuolar protein-sorting-associated protein 4 ko04144 Endocytosis 72 2

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003887 DNA-directed DNA polymerase activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0004127 cytidylate kinase activity
GO:0016787 hydrolase activity
GO:0009378 four-way junction helicase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004161 dimethylallyltranstransferase activity
GO:0004673 protein histidine kinase activity
GO:0000723 telomere maintenance
GO:0003972 RNA ligase (ATP) activity
GO:0016740 transferase activity
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0015937 coenzyme A biosynthetic process
GO:0003724 RNA helicase activity
GO:0006139 nucleobase-containing compound metabolic process
GO:0016020 membrane
GO:0051188 cofactor biosynthetic process
GO:0016887 ATPase activity
GO:0004140 dephospho-CoA kinase activity
GO:0006270 DNA replication initiation
GO:0009236 cobalamin biosynthetic process
GO:0000160 phosphorelay signal transduction system
GO:0008134 transcription factor binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0043531 ADP binding
GO:0000155 phosphorelay sensor kinase activity
GO:0009058 biosynthetic process
GO:0009360 DNA polymerase III complex
GO:0004797 thymidine kinase activity
GO:0008026 ATP-dependent helicase activity
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0006281 DNA repair
GO:0004003 ATP-dependent DNA helicase activity
GO:0003723 RNA binding
GO:0005524 ATP binding

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