phrog_9285 is made of 12 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
183.92 538 122


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_018853_p46 YP_006907222.1 putative regulator, GntR family NC_018853 Streptomyce phage TG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tigunavirus.
MG593802_p50 AUG87235.1 helix-turn-helix DNA binding domain protein MG593802 Streptomyces phage Omar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
p71519 no NCBI prot ID no annotation VI_00059 Actinobacteria_gi_485069185 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p260070 no NCBI prot ID no annotation VI_05344 Bacilli_gi_544867302 Viruses; unclassified bacterial viruses.
p342668 no NCBI prot ID no annotation VI_05383 Bacilli_gi_553744317 Viruses.
p350167 no NCBI prot ID no annotation VI_05356 Bacilli_gi_544931225 Viruses.
MF766047_p2 ATI18865.1 helix-turn-helix DNA binding domain protein MF766047 Streptomyces phage SqueakyClean Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Arquatrovirinae; Arequatrovirus; unclassified Arequatrovirus.
p18188 no NCBI prot ID no annotation VI_00421 Bacilli_gi_423480041 Viruses.
p27353 no NCBI prot ID no annotation VI_00039 Actinobacteria_gi_483966370 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p14144 no NCBI prot ID no annotation VI_01294 Clostridia_gi_512436394 Viruses.
p27363 no NCBI prot ID no annotation VI_00039 Actinobacteria_gi_483966370 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p26516 no NCBI prot ID no annotation VI_00260 Bacilli_gi_487344359 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10724 no annotation unknown function 99.6 7.6E-19 6-79 / 3-76
phrog_1098 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.0 0.013 37-74 / 42-83
phrog_13105 no annotation unknown function 95.4 0.00077 27-83 / 13-69
phrog_1368 transcriptional regulator transcription regulation 92.5 0.019 25-73 / 22-66
phrog_142 Ren-like exclusion protein moron, auxiliary metabolic gene and host takeover 90.7 0.048 36-73 / 18-55
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 95.7 0.00035 30-80 / 8-67
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 94.3 0.0037 30-68 / 46-84
phrog_2418 no annotation unknown function 95.3 0.00081 34-68 / 56-90
phrog_2440 transcriptional regulator transcription regulation 92.1 0.024 38-74 / 28-65
phrog_2514 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 92.9 0.014 27-75 / 48-106
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 95.3 0.00092 31-68 / 35-72
phrog_27344 replication initiation protein DNA, RNA and nucleotide metabolism 95.7 0.00036 34-72 / 40-79
phrog_3502 no annotation unknown function 96.2 8E-05 32-68 / 23-60
phrog_38247 no annotation unknown function 98.2 1.2E-09 3-87 / 3-86
phrog_391 replication initiation O-like DNA, RNA and nucleotide metabolism 92.7 0.017 20-68 / 26-74
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 94.5 0.0032 29-70 / 43-84
phrog_4617 replication initiation protein DNA, RNA and nucleotide metabolism 92.9 0.014 16-67 / 18-71
phrog_5978 no annotation unknown function 90.8 0.046 33-70 / 319-356
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 93.2 0.012 33-72 / 46-86
phrog_7498 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 94.5 0.0031 25-75 / 47-98
phrog_769 transcriptional repressor transcription regulation 90.1 0.063 13-57 / 15-48
phrog_7882 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 93.0 0.014 15-72 / 42-96
phrog_8046 no annotation unknown function 91.2 0.039 36-67 / 58-89
phrog_8102 replication initiation protein DNA, RNA and nucleotide metabolism 94.3 0.0039 32-71 / 45-84

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF12897.6 Alanine-glyoxylate amino-transferase 4.1E-21 166-499 / 62-419
PF00155.20 Aminotransferase class I and II 2E-19 166-489 / 33-384
PF02347.15 Glycine cleavage system P-protein 6.4E-17 168-489 / 102-424
PF00282.18 Pyridoxal-dependent decarboxylase conserved domain 9.5E-17 163-355 / 66-288
PF04864.12 Allinase 2.1E-16 166-492 / 32-359
PF00266.18 Aminotransferase class-V 2.6E-16 167-485 / 38-369
PF00464.18 Serine hydroxymethyltransferase 5.8E-16 173-489 / 63-377
PF00202.20 Aminotransferase class-III 2.3E-15 171-492 / 64-381
PF01276.19 Orn/Lys/Arg decarboxylase, major domain 2.5E-15 195-356 / 83-264
PF01053.19 Cys/Met metabolism PLP-dependent enzyme 6.1E-15 175-359 / 46-215
PF03841.12 L-seryl-tRNA selenium transferase 7.3E-15 195-361 / 63-234
PF01041.16 DegT/DnrJ/EryC1/StrS aminotransferase family 9.4E-15 171-354 / 22-195
PF01212.20 Beta-eliminating lyase 3.3E-14 167-361 / 27-218
PF05889.12 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 6.7E-14 197-356 / 40-185
PF06838.10 Methionine gamma-lyase 3.2E-13 174-360 / 57-247
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.4E-05 67-100 / 24-57
PF04492.12 Bacteriophage replication protein O 1.6E-05 66-108 / 49-91
PF09824.8 ArsR transcriptional regulator 2.2E-05 39-99 / 6-61
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 3.6E-05 67-100 / 23-56
PF09012.9 FeoC like transcriptional regulator 4.5E-05 67-103 / 15-51
PF11313.7 Protein of unknown function (DUF3116) 5.4E-05 68-116 / 22-78
PF07381.10 Winged helix DNA-binding domain (DUF1495) 6.3E-05 67-100 / 25-68
PF14277.5 Domain of unknown function (DUF4364) 0.0001 67-115 / 16-68
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00015 67-99 / 28-60
PF08222.10 CodY helix-turn-helix domain 0.00017 67-100 / 5-38
PF02334.15 Replication terminator protein 0.00017 68-116 / 33-99
PF13601.5 Winged helix DNA-binding domain 0.00018 67-101 / 15-49
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.00018 67-109 / 17-61
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00019 67-107 / 27-67
PF02002.16 TFIIE alpha subunit 0.00019 67-101 / 27-61
PF03551.13 Transcriptional regulator PadR-like family 0.00021 67-101 / 15-51
PF14394.5 Domain of unknown function (DUF4423) 0.00024 46-101 / 17-73
PF16221.4 winged helix-turn-helix 0.00024 67-98 / 47-78
PF03965.15 Penicillinase repressor 0.00025 67-111 / 19-68
PF05584.10 Sulfolobus plasmid regulatory protein 0.00026 67-100 / 19-52
PF02295.16 Adenosine deaminase z-alpha domain 0.00027 67-100 / 19-53
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00028 68-90 / 53-75
PF07848.11 PaaX-like protein 0.00031 67-108 / 21-65
PF00392.20 Bacterial regulatory proteins, gntR family 0.00037 68-100 / 26-58
PF01726.15 LexA DNA binding domain 0.00043 67-101 / 26-61
PF09114.9 Transcription factor MotA, activation domain 0.00042 67-100 / 31-65
PF12840.6 Helix-turn-helix domain 0.00044 67-100 / 24-54
PF10711.8 Hypothetical protein (DUF2513) 0.00046 68-101 / 20-57
PF01090.18 Ribosomal protein S19e 0.00046 67-101 / 66-115
PF08784.10 Replication protein A C terminal 0.00048 67-100 / 59-95
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00052 67-104 / 23-60
PF04079.15 Segregation and condensation complex subunit ScpB 0.00052 67-115 / 98-147
PF14947.5 Winged helix-turn-helix 0.00064 67-100 / 17-50
PF09904.8 Winged helix-turn helix 0.00065 67-98 / 22-53
PF13463.5 Winged helix DNA-binding domain 0.00078 67-99 / 18-50
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00078 67-100 / 19-52
PF02082.19 Transcriptional regulator 0.00082 67-100 / 25-58
PF15977.4 Winged helix-turn-helix DNA binding 0.00083 67-100 / 24-57
PF04182.11 B-block binding subunit of TFIIIC 0.00088 67-101 / 19-53
PF14557.5 Putative AphA-like transcriptional regulator 0.00095 67-115 / 26-85
PF01638.16 HxlR-like helix-turn-helix 0.0011 67-101 / 20-55
PF04358.12 DsrC like protein 0.0012 66-99 / 58-94
PF01475.18 Ferric uptake regulator family 0.0014 67-102 / 23-63
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0015 66-101 / 75-110
PF03428.12 Replication protein C N-terminal domain 0.0015 67-101 / 71-106
PF12802.6 MarR family 0.0016 67-100 / 22-55
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0016 67-105 / 23-61
PF09202.10 Rio2, N-terminal 0.0019 67-100 / 25-58
PF14502.5 Helix-turn-helix domain 0.002 67-100 / 7-40
PF09639.9 YjcQ protein 0.0021 67-100 / 17-52
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.0021 69-115 / 29-75
PF09182.9 Bacterial purine repressor, N-terminal 0.0024 67-100 / 21-59
PF09339.9 IclR helix-turn-helix domain 0.0028 67-99 / 19-51
PF05158.11 RNA polymerase Rpc34 subunit 0.0029 66-101 / 108-143
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0032 67-100 / 22-55
PF13545.5 Crp-like helix-turn-helix domain 0.0033 67-99 / 28-60
PF03297.14 S25 ribosomal protein 0.0036 67-99 / 57-89
PF01316.20 Arginine repressor, DNA binding domain 0.0038 67-108 / 20-63
PF06969.15 HemN C-terminal domain 0.0039 67-99 / 21-54
PF08679.10 Dissimilatory sulfite reductase D (DsrD) 0.0038 67-108 / 17-59
PF01022.19 Bacterial regulatory protein, arsR family 0.0046 67-96 / 17-46
PF01047.21 MarR family 0.0047 67-100 / 18-51
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0058 68-99 / 13-47
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0064 67-99 / 18-50
PF04703.11 FaeA-like protein 0.0066 67-100 / 15-48
PF11972.7 HTH DNA binding domain 0.0065 67-97 / 14-41
PF08220.11 DeoR-like helix-turn-helix domain 0.008 67-100 / 15-48
PF05331.10 Protein of unknown function (DUF742) 0.0078 67-101 / 54-88
PF13412.5 Winged helix-turn-helix DNA-binding 0.0092 67-96 / 18-47
PF08461.9 Ribonuclease R winged-helix domain 0.0092 67-100 / 13-51
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0094 67-100 / 25-58

Annotations of the NCBI proteins of this PHROG


2:helix-turn-helix DNA binding domain protein 1:regulator, GntR family

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00375 K00375 : GntR family transcriptional regulator / MocR family aminotransferase no pathways 400 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006468 protein phosphorylation
GO:0003700 DNA binding transcription factor activity
GO:0055114 oxidation-reduction process
GO:0006274 DNA replication termination
GO:0009058 biosynthetic process
GO:0016829 lyase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0004674 protein serine/threonine kinase activity
GO:0007131 reciprocal meiotic recombination
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0003824 catalytic activity
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0019752 carboxylic acid metabolic process
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0016831 carboxy-lyase activity
GO:0016846 carbon-sulfur lyase activity
GO:0004375 glycine dehydrogenase (decarboxylating) activity
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0005840 ribosome
GO:0005667 transcription factor complex
GO:0009289 pilus
GO:0006260 DNA replication
GO:0008483 transaminase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0004252 serine-type endopeptidase activity
GO:0006546 glycine catabolic process
GO:0006520 cellular amino acid metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0006412 translation
GO:0006525 arginine metabolic process

Loading in process