phrog_9381 is made of 11 protein sequences and is annotated as "replication initiation by nicking"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
282 397 279


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028983_p147 YP_009216145.1 hypothetical protein NC_028983 Bacillus phage Shanette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_009760_p101 YP_001429691.1 hypothetical protein NC_009760 Bacillus phage 0305phi8-36 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
KY368639_p123 APZ82363.1 plasmid replication-relaxation protein KY368639 Bacillus phage vB_BsuM-Goe2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus; unclassified Okubovirus; Bacillus virus vB_BsuM-Goe2.
NC_025423_p76 YP_009099120.1 hypothetical protein NC_025423 Bacillus phage CP-51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_028982_p145 YP_009215925.1 hypothetical protein NC_028982 Bacillus phage JL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Siminovitchvirus.
NC_022761_p128 YP_008770062.1 plasmid replication-relaxation protein NC_022761 Bacillus phage CampHawk Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
NC_011421_p126 YP_002300402.1 gp27.3 NC_011421 Bacillus virus SPO1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
NC_023719_p138 YP_009015449.1 gp146 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_023007_p256 YP_008873498.1 hypothetical protein NC_023007 Bacillus phage vB_BanS-Tsamsa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KT070867_p242 AKQ08557.1 hypothetical protein KT070867 Bacillus phage PBC2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p265146 no NCBI prot ID no annotation VI_04166 Actinobacteria_gi_564018020 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_5156 25 no annotation unknown function 9 2.25E-45 35.77

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_2190 replication initiation protein DNA, RNA and nucleotide metabolism 98.7 1E-11 30-253 / 2-182
phrog_9996 no annotation unknown function 95.9 0.00022 29-238 / 3-163

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13814.5 Replication-relaxation 6.7E-16 49-236 / 1-152
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 4.5E-06 40-126 / 5-91
PF14557.5 Putative AphA-like transcriptional regulator 1.6E-05 39-128 / 4-90
PF04079.15 Segregation and condensation complex subunit ScpB 2.4E-05 39-127 / 79-151
PF11313.7 Protein of unknown function (DUF3116) 2.5E-05 46-127 / 10-81
PF07381.10 Winged helix DNA-binding domain (DUF1495) 2.9E-05 40-125 / 6-88
PF05584.10 Sulfolobus plasmid regulatory protein 3.2E-05 40-124 / 3-71
PF03551.13 Transcriptional regulator PadR-like family 4.8E-05 49-126 / 2-73
PF02334.15 Replication terminator protein 5.1E-05 45-128 / 20-103
PF09114.9 Transcription factor MotA, activation domain 6.2E-05 38-128 / 11-81
PF13463.5 Winged helix DNA-binding domain 6.5E-05 42-121 / 2-67
PF01090.18 Ribosomal protein S19e 0.00011 41-127 / 49-134
PF03965.15 Penicillinase repressor 0.00013 41-125 / 1-74
PF13601.5 Winged helix DNA-binding domain 0.00014 46-127 / 3-71
PF14277.5 Domain of unknown function (DUF4364) 0.00015 46-127 / 3-72
PF09639.9 YjcQ protein 0.00023 47-128 / 2-83
PF10711.8 Hypothetical protein (DUF2513) 0.00029 46-128 / 8-85
PF01638.16 HxlR-like helix-turn-helix 0.0003 43-127 / 5-76
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.00043 40-127 / 2-79
PF09202.10 Rio2, N-terminal 0.00048 40-126 / 3-75
PF04492.12 Bacteriophage replication protein O 0.00058 38-101 / 22-83
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00063 46-127 / 5-74
PF14947.5 Winged helix-turn-helix 0.00091 45-127 / 4-70
PF02002.16 TFIIE alpha subunit 0.0011 44-126 / 13-82
PF04358.12 DsrC like protein 0.0011 39-101 / 35-95
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0013 39-101 / 50-109
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0016 41-100 / 11-60
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0017 41-127 / 2-76
PF01475.18 Ferric uptake regulator family 0.0018 39-101 / 3-61
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0018 41-101 / 5-57
PF14394.5 Domain of unknown function (DUF4423) 0.0019 42-124 / 20-88
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0022 40-101 / 5-56
PF05158.11 RNA polymerase Rpc34 subunit 0.0026 39-102 / 88-143
PF03428.12 Replication protein C N-terminal domain 0.0031 39-102 / 39-106
PF16221.4 winged helix-turn-helix 0.0039 44-99 / 32-78
PF08784.10 Replication protein A C terminal 0.0047 38-101 / 35-95
PF08461.9 Ribonuclease R winged-helix domain 0.006 48-124 / 3-64
PF13034.5 Protein of unknown function (DUF3895) 0.0065 42-102 / 2-68
PF01047.21 MarR family 0.0065 42-101 / 2-51
PF09012.9 FeoC like transcriptional regulator 0.0071 48-102 / 5-49
PF14338.5 Mrr N-terminal domain 0.0073 81-126 / 51-86
PF12802.6 MarR family 0.008 41-101 / 3-55

Annotations of the NCBI proteins of this PHROG


7:hypothetical protein 2:plasmid replication-relaxation protein 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006412 translation
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0003735 structural constituent of ribosome
GO:0006274 DNA replication termination
GO:0005840 ribosome
GO:0003700 DNA binding transcription factor activity
GO:0003677 DNA binding
GO:0006468 protein phosphorylation
GO:0004674 protein serine/threonine kinase activity
GO:0006260 DNA replication
GO:0006383 transcription by RNA polymerase III
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex

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