phrog_9443 is made of 11 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
169.64 170 170


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF919494_p21 ATN87479.1 HNH endonuclease MF919494 Mycobacterium phage BeanWater Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
MH051261_p27 AVR77952.1 HNH endonuclease domain protein MH051261 Mycobacterium phage Tyke Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
MG872839_p26 AVI04630.1 HNH endonuclease MG872839 Mycobacterium phage LifeSavor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
MG812494_p27 AVJ48539.1 HNH endonuclease MG812494 Mycobacterium phage Pier Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
MH051260_p32 AVR77539.1 hypothetical protein MH051260 Mycobacterium phage InterFolia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
KT365398_p26 ALF50889.1 HNH endonuclease KT365398 Mycobacterium phage DTDevon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_021348_p25 YP_008061283.1 HNH endonuclease domain protein NC_021348 Mycobacterium phage ArcherS7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
KX369583_p25 ANT41563.1 HNH endonuclease KX369583 Mycobacterium phage Littleton Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_028869_p24 YP_009204589.1 HNH endonuclease NC_028869 Mycobacterium phage HyRo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_023696_p30 YP_009012808.1 gp29 NC_023696 Mycobacterium phage Dandelion Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
JF704096_p26 AEJ94999.1 hypothetical protein JF704096 Mycobacterium phage Ghost Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_549 251 no annotation unknown function 11 1.09E-37 28.08
phrog_2690 53 no annotation unknown function 11 2.92E-46 36.66

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 94.8 0.002 98-145 / 101-153
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.042 99-156 / 106-167
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 95.5 0.00054 95-144 / 143-199
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.013 99-148 / 132-185
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 9.8E-06 85-145 / 6-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0056 90-141 / 30-76
phrog_26098 no annotation unknown function 95.1 0.0013 100-146 / 136-187
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.5E-05 94-145 / 24-83
phrog_4160 no annotation unknown function 98.3 6.5E-10 70-164 / 34-140
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0027 100-144 / 25-70
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 93.5 0.0088 99-141 / 51-95
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 88-141 / 17-75
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 92.6 0.018 97-141 / 38-83
phrog_99 HNH endonuclease DNA, RNA and nucleotide metabolism 91.5 0.033 79-134 / 47-88

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05766.11 Bacteriophage Lambda NinG protein 1.7E-07 80-147 / 71-138
PF13395.5 HNH endonuclease 4E-07 101-145 / 1-51
PF05315.10 ICEA Protein 1.4E-06 82-145 / 80-150
PF01844.22 HNH endonuclease 3.3E-06 101-144 / 1-47
PF14279.5 HNH endonuclease 3.4E-06 101-148 / 1-48
PF06147.10 Protein of unknown function (DUF968) 5.3E-05 99-146 / 128-175
PF13391.5 HNH endonuclease 5.8E-05 101-145 / 1-45
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00023 99-147 / 254-298
PF16784.4 Putative HNHc nuclease 0.0039 99-146 / 124-172

Annotations of the NCBI proteins of this PHROG


6:HNH endonuclease 3:hypothetical protein 2:HNH endonuclease domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

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