phrog_9545 is made of 11 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
196.45 251 206


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019408_p313 YP_006989342.1 putative HNH homing endonuclease NC_019408 Caulobacter virus Rogue Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phicbkvirus.
NC_019405_p305 YP_006988201.1 hypothetical protein NC_019405 Caulobacter virus phiCbK Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus.
NC_019407_p315 YP_006988997.1 putative HNH homing endonuclease NC_019407 Caulobacter virus Magneto Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019410_p321 YP_006989701.1 putative HNH homing endonuclease NC_019410 Caulobacter virus Karma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
KY555143_p312 ARB14186.1 hypothetical protein KY555143 Caulobacter phage Ccr2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
KY555144_p309 ARB14527.1 hypothetical protein KY555144 Caulobacter phage Ccr5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019411_p312 YP_006990045.1 putative HNH homing endonuclease NC_019411 Caulobacter virus Swift Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus.
KY555145_p322 ARB14880.1 hypothetical protein KY555145 Caulobacter phage Ccr29 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dolichocephalovirinae; Shapirovirus; unclassified Shapirovirus.
NC_019917_p21 YP_007236767.1 HNH endonuclease NC_019917 Burkholderia virus Bcepmigl Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Lessievirus.
p90617 no NCBI prot ID no annotation VI_07561 Gammaproteobacteria_gi_482731795_13697_59971 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p386860 no NCBI prot ID no annotation VI_04155 Actinobacteria_gi_544775493 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_12253 8 no annotation unknown function 8 0 1000
phrog_12758 8 no annotation unknown function 7 3.00E-38 28.65

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 97.3 1E-06 104-176 / 95-162
phrog_11718 no annotation unknown function 95.1 0.0012 21-99 / 18-89
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 96.0 0.00018 101-167 / 22-82
phrog_12576 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 4.4E-11 99-191 / 17-114
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.3E-05 107-168 / 143-201
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.4E-08 101-169 / 7-66
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.3E-06 101-166 / 53-112
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 104-188 / 125-200
phrog_1571 HNH endonuclease DNA, RNA and nucleotide metabolism 95.1 0.0013 136-167 / 63-89
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 1.2E-09 101-168 / 71-131
phrog_16986 no annotation unknown function 97.7 7.4E-08 100-169 / 10-70
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 94.3 0.0039 130-168 / 5-44
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.6E-08 100-180 / 6-87
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 1.5E-13 94-202 / 18-118
phrog_22283 no annotation unknown function 91.7 0.03 108-165 / 19-69
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 91.5 0.034 102-165 / 17-87
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 92.2 0.023 132-168 / 89-125
phrog_24252 HNH endonuclease DNA, RNA and nucleotide metabolism 90.9 0.044 104-174 / 9-81
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0022 129-179 / 122-171
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.00041 112-167 / 11-69
phrog_26098 no annotation unknown function 91.6 0.032 104-169 / 128-188
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.1E-07 101-166 / 19-72
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 90.3 0.058 103-170 / 12-78
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 3.4E-09 106-171 / 24-87
phrog_4581 terminase small subunit head and packaging 95.7 0.00036 91-166 / 36-107
phrog_4707 replication initiation protein DNA, RNA and nucleotide metabolism 94.5 0.0031 17-97 / 18-91
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 4.4E-10 101-178 / 14-81
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.5E-08 101-169 / 41-101
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 6.9E-05 106-168 / 2-58
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 8.6E-09 109-171 / 4-58
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 3.9E-05 93-162 / 24-81
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.3E-06 102-180 / 60-126
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0022 101-166 / 120-186
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 98.5 7.4E-11 98-173 / 98-161
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0046 109-169 / 36-89
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 9.3E-07 101-171 / 15-79

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 6.1E-09 104-174 / 79-149
PF13395.5 HNH endonuclease 5.9E-08 121-174 / 1-50
PF01844.22 HNH endonuclease 2.2E-07 121-173 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 7.2E-07 107-175 / 75-136
PF14279.5 HNH endonuclease 8.7E-07 121-175 / 1-45
PF06970.10 Replication initiator protein A (RepA) N-terminus 3E-06 24-88 / 3-75
PF13391.5 HNH endonuclease 3.5E-06 121-174 / 1-44
PF06147.10 Protein of unknown function (DUF968) 1.1E-05 117-174 / 126-173
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 1.9E-05 118-176 / 253-297
PF04492.12 Bacteriophage replication protein O 0.00015 25-98 / 11-83
PF16784.4 Putative HNHc nuclease 0.00028 117-174 / 122-170
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0076 59-97 / 23-56

Annotations of the NCBI proteins of this PHROG


4:hypothetical protein 4:HNH homing endonuclease 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006260 DNA replication
GO:0003700 DNA binding transcription factor activity
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding
GO:0006355 regulation of transcription, DNA-templated
GO:0005667 transcription factor complex

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