phrog_9645 is made of 11 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
174.27 192 177


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_029098_p100 YP_009225826.1 terminase associated HNH endonuclease NC_029098 Streptomyces phage Jay2Jay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Jay2Jay.
MF347636_p92 ASR77361.1 HNH endonuclease MF347636 Streptomyces phage NootNoot Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus NootNoot.
MF668286_p117 ASZ74931.1 HNH endonuclease MF668286 Rhodococcus phage Trina Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Trinavirus; Rhodococcus virus Trina.
MF347639_p96 AST15328.1 HNH endonuclease MF347639 Streptomyces phage Samisti12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Samisti12.
MF358541_p99 ASN73174.1 terminase associated HNH endonuclease MF358541 Streptomyces phage Warpy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF358542_p95 ASR76527.1 terminase associated HNH endonuclease MF358542 Streptomyces phage Sushi23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; unclassified Samistivirus.
MF347638_p95 ASR77801.1 HNH endonuclease MF347638 Streptomyces phage Peebs Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Peebs.
MG757153_p78 AVD99283.1 HNH endonuclease MG757153 Streptomyces phage BillNye Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wilnyevirus; Streptomyces virus BillNye.
MF155946_p95 ASR75503.1 HNH endonuclease MF155946 Streptomyces phage Mildred21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Mildred21.
KX774321_p115 AOZ63704.1 terminase associated HNH endonuclease KX774321 Rhodococcus phage Weasels2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Weaselvirus; Rhodococcus virus Weasel.
MF347637_p92 ASR77577.1 HNH endonuclease MF347637 Streptomyces phage Paradiddles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samistivirus; Streptomyces virus Paradiddles.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2 5795 terminase large subunit head and packaging 10 5.16E-19 9.41
phrog_7371 16 no annotation unknown function 5 8.09E-25 15.21
phrog_20718 4 no annotation unknown function 3 2.68E-19 9.69

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.1 2.6E-09 18-80 / 95-158
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 92.6 0.018 18-75 / 25-82
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.9E-06 21-77 / 143-202
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.1E-06 21-98 / 13-87
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 96.5 2.8E-05 18-74 / 56-112
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.7E-05 6-88 / 113-194
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 7.8E-10 17-80 / 73-135
phrog_16986 no annotation unknown function 97.1 2.3E-06 19-83 / 15-76
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.1E-07 41-79 / 8-47
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.2E-07 17-75 / 9-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 98.2 2.3E-09 16-81 / 27-86
phrog_22283 no annotation unknown function 96.4 4.7E-05 26-79 / 22-75
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.042 34-76 / 24-70
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.0009 15-75 / 19-73
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 1.2E-12 20-79 / 24-87
phrog_4581 terminase small subunit head and packaging 96.6 1.9E-05 15-81 / 53-114
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 9.6E-14 14-77 / 13-73
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 3E-07 13-76 / 39-100
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 92.9 0.015 20-78 / 2-60
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.9 7.4E-13 27-77 / 6-56
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 42-63 / 23-44
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 6.3E-09 13-75 / 57-112
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 91.2 0.038 17-71 / 122-183
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 98.6 4.1E-11 18-79 / 104-159
phrog_9508 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 7.4E-05 42-78 / 41-77
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 3.5E-07 15-79 / 101-171
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0057 12-79 / 20-91

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 2.6E-06 46-79 / 18-51
PF05315.10 ICEA Protein 8.6E-06 17-79 / 82-150
PF01844.22 HNH endonuclease 9.1E-06 46-78 / 12-47
PF14279.5 HNH endonuclease 3.1E-05 45-79 / 12-45
PF05766.11 Bacteriophage Lambda NinG protein 6E-05 19-79 / 77-136
PF13391.5 HNH endonuclease 9.8E-05 45-79 / 11-45
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00036 45-80 / 263-297
PF06147.10 Protein of unknown function (DUF968) 0.0029 28-78 / 127-173

Annotations of the NCBI proteins of this PHROG


7:HNH endonuclease 4:terminase associated HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00986 E2.7.7.49 : RNA-directed DNA polymerase [EC:2.7.7.49] no pathways 57 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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